Condition

Burkitt Lymphoma clinical trials and research

• 23Clinical trials
• 5NIH research projects
• 35Countries

Newest Burkitt Lymphoma clinical trials

All recruiting trials (23)

• Epcoritamab plus dose‑adjusted EPOCH‑R for aggressive B‑cell lymphoma

  This trial tests whether adding epcoritamab to dose‑adjusted EPOCH‑R chemotherapy can safely improve outcomes for adults with untreated aggressive B‑cell non‑Hodgkin lymphoma.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT07097363

• CX-5461 (Pidnarulex) for aggressive B‑cell lymphomas with MYC gene changes

  This trial tests whether the IV drug CX-5461 (Pidnarulex) is safe and can shrink or control aggressive B‑cell lymphomas that have MYC gene changes in adults who have already had other treatments.

  Recruiting at 8 sites Phase 1/2 National Cancer Institute (NCI) · Irvine, California and 7 other locations · NCT07069699

• Comparing advanced and classical immunotherapy for lymphoma treatment

  This study is testing whether newer immunotherapy treatments for high-grade B cell lymphoma work better and are safer than traditional methods for adults who have already had treatment that didn't work.

  Recruiting at 2 sites Seoul St. Mary's Hospital · Seoul and 1 other locations · NCT06796517

• Gene therapy for certain blood cancers

  This study is testing a new gene therapy called VNX-101 to see if it can help people with certain types of blood cancers that haven't responded to other treatments.

  Recruiting at 11 sites Phase 1/2 Vironexis Biotherapeutics Inc. · Duarte, California and 10 other locations · NCT06533579

• Zilovertamab Vedotin for Pediatric and Young Adult Cancer Patients

  This study is testing a new drug called zilovertamab vedotin to see if it can help kids and young adults with certain types of cancer that haven't responded to other treatments.

  Recruiting at 70 sites Phase 1/2 Merck Sharp & Dohme LLC · Los Angeles, California and 70 other locations · NCT06395103

• Using CAR T cells to treat certain types of B cell lymphomas

  This study is testing a new CAR T cell therapy to see if it can help adults with certain types of B cell lymphomas that haven't improved with other treatments.

  Recruiting Phase 1 Stanford University · Palo Alto, California · NCT06340737

• Study of crushed venetoclax tablets dissolved in liquid for pediatric patients

  This study tests if crushing venetoclax tablets and mixing them with liquid helps children with blood cancers absorb the medication better and stay safe while taking it.

  Recruiting at 5 sites Children's Hospital Medical Center, Cincinnati · Aurora, Colorado and 5 other locations · NCT06131801

• Treatment for adult patients with specific types of lymphoma and leukemia

  This study is testing a new treatment plan using a combination of medications before a stem cell transplant to see if it helps adults with certain types of lymphoma and leukemia stay in remission.

  Recruiting Phase 1 Fifth Affiliated Hospital, Sun Yat-Sen University · Zhuhai, Guangdong · NCT06060782

• Using LV20.19 CAR T-Cells with Pirtobrutinib for B-cell Malignancies

  This study is testing a new treatment combining LV20.19 CAR T-cells with pirtobrutinib to see if it helps adults with tough-to-treat B-cell cancers feel better.

  Recruiting Phase 1 Medical College of Wisconsin · Milwaukee, Wisconsin · NCT05990465

• Stem cell transplant using a specific preparative regimen for blood cancers

  This study is testing a new way to prepare for a stem cell transplant using a special combination of medications and radiation to see if it helps people with acute leukemia who are in remission.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT05805605

• Targeted T-Cell and B-Cell Depletion for Hematologic Malignancies

  This study is testing a new way to prepare patients with blood cancers for stem cell transplants by removing certain immune cells to see if it helps them recover better and stay healthy longer.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT05794880

• Evaluating SGR-1505 for treating mature B-cell neoplasms

  This study is testing a new oral medication called SGR-1505 to see if it is safe and effective for people with certain types of B-cell lymphomas that have not responded to other treatments.

  Recruiting at 36 sites Phase 1 Schrödinger, Inc. · Gilbert, Arizona and 35 other locations · NCT05544019

• Treatment protocol for B-cell mature non-Hodgkin's lymphoma in children and adolescents

  This study is testing different treatment plans for children and teenagers with B-cell non-Hodgkin's lymphoma to see who needs stronger therapy and who can safely have gentler options.

  Recruiting Phase 4 Federal Research Institute of Pediatric Hematology, Oncology and Immunology · Moscow, RF · NCT05518383

• Combining Pomalidomide with Chemotherapy for HIV-Related Lymphomas

  This study is testing if adding a drug called pomalidomide to chemotherapy can help adults with HIV-related lymphomas feel better and improve their treatment outcomes.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05389423

• Using modified T cells to treat relapsed or refractory Non-Hodgkin Lymphoma

  This study is testing a new treatment using modified T cells to see if it can help people with relapsed or hard-to-treat Non-Hodgkin Lymphoma.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT04545762

• Using stem cell transplant and Polatuzumab Vedotin for treating B-cell lymphomas

  This study is testing if a stem cell transplant followed by a new drug called Polatuzumab Vedotin can help people with different types of B-cell lymphomas feel better.

  Recruiting Phase 1/2 New York Medical College · Valhalla, New York · NCT04491370

• Evaluating treatment recommendations for children with Burkitt's Lymphoma

  This study is trying to find better ways to diagnose and treat children with Burkitt's Lymphoma in Sub-Saharan Africa to improve their chances of recovery.

  Recruiting at 7 sites French Africa Pediatric Oncology Group · Ouagadougou and 6 other locations · NCT04425421

• Donor stem cell transplant with chemotherapy and radiation for blood cancers

  This study is testing if a donor stem cell transplant combined with different doses of chemotherapy and radiation can help people with blood cancers recover better.

  Recruiting Phase 2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT04195633

• Using CD45RA Depleted Stem Cells to Improve Immune Recovery After Transplant

  This study is testing if using special stem cells can help patients with acute leukemia recover their immune system faster after a transplant and reduce the risk of complications.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT03810196

• Long-term follow-up of patients receiving CAR-T cell therapy

  This study is tracking patients who have received CAR-T cell therapy for up to 15 years to see how well the treatment works over time and if there are any long-term health issues.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT03375619

• Hematopoietic stem cell transplant for blood cancers

  This study is testing two different ways of doing stem cell transplants for people with blood cancers to see which method works better and is safer.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT03314974

• Combination treatment for relapsed B-cell lymphoma

  This study is testing a new combination of five drugs to see if it can help people with relapsed or hard-to-treat B-cell lymphoma feel better.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT03223610

• Using obinutuzumab with chemotherapy for relapsed CD20+ Non-Hodgkin Lymphoma in young patients

  This study is testing if a new drug called obinutuzumab, alone or with chemotherapy, can help young patients with relapsed CD20 positive Non-Hodgkin Lymphoma feel better and improve their treatment results.

  Recruiting Phase 2 New York Medical College · Valhalla, New York · NCT02393157

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Organoid model to study how malaria and EBV drive Burkitt lymphoma in children

  A study uses human tonsillar organoids to understand how malaria parasite infection and EBV together may cause a type of lymphoma in children from sub-Saharan Africa.

  NIH research Univ of Arkansas for Med Scis · Little Rock, United States · NIH-11445198

• Enriching tumor-derived EBV DNA to build a diagnostic test for endemic Burkitt lymphoma (eBL)

  A study to develop a blood-based test that specifically detects tumor-derived EBV DNA to improve early diagnosis of endemic Burkitt lymphoma in children.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11311868

• Improving diagnosis of Burkitt lymphoma in children using blood tests.

  This study is looking at a new way to help doctors quickly and accurately diagnose endemic Burkitt lymphoma in children by checking for a specific virus in their blood, which could lead to faster treatment and better outcomes.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11061865

• Investigating methotrexate dosing and effects for Burkitt lymphoma in Malawi

  This study is looking to make treatments better for kids and young adults with Burkitt lymphoma by testing the safest dose of a chemotherapy drug called methotrexate and finding out how it works in the body, all while keeping an eye on how patients feel during treatment.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10924460

• Investigating methotrexate dosing and side effects for Burkitt lymphoma in Malawi

  This study is looking to make treatments better for kids and young adults with Burkitt lymphoma in Sub-Saharan Africa by testing the safest dose of a chemotherapy drug called methotrexate and finding out how it works in the body, while also listening to patients about any side effects they experience.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10650283

Related topics

Quick answers

How many Burkitt Lymphoma clinical trials are recruiting right now?

23, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 35 countries. The most sites are in United States (19 trials), France (2 trials), Italy (2 trials), South Korea (2 trials), Spain (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 6, Phase 1/2: 5, Phase 2: 5, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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