Preventing the progression of follicular lymphoma with targeted therapy
Preventing follicular lymphoma progression and transformation through precision therapy
['FUNDING_R01'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11109606
This study is looking at how slow-growing follicular lymphomas can change into more aggressive forms, and it's working to find personalized treatments that target the specific factors that help these tumors survive, so we can help patients live better and longer.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11109606 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how follicular lymphomas, which are slow-growing tumors derived from B-cells, can progress and transform into more aggressive forms. The study aims to develop precision therapies that target the unique genetic and environmental factors that allow these tumors to survive and resist treatment. By investigating the role of specific mutations and the tumor microenvironment, the research seeks to create effective treatment strategies that can prevent disease progression and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with follicular lymphoma who are at risk of disease progression or transformation.
Not a fit: Patients with aggressive forms of lymphoma that are not follicular in nature may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that effectively prevent the progression of follicular lymphoma and improve survival rates for patients.
How similar studies have performed: Previous research has shown promise in targeting genetic mutations in lymphomas, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BEGUELIN, WENDY — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: BEGUELIN, WENDY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.