Clinical trial Recruiting at 1 site Observational Ages 18 and up

Italian Cardiac Rehabilitation Registry for Coronary Disease and Heart Failure

Official title: The ITACARE-P CardioRehab Registry

Run by Fondazione Don Carlo Gnocchi ETS · NCT07094737 · Data updated 2026-11-12

This registry collects real-world information to see how cardiac rehabilitation programs work for adults recovering from coronary disease or heart failure across Italy.

More Heart Failure trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1600 (estimated)
SponsorFondazione Don Carlo Gnocchi ETS
Academic / other
Locations1 site (Milan)
StatusRecruiting
StartedMay 1, 2025
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedSeptember 29, 2026
Trial IDNCT07094737 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with coronary artery disease and/or heart failure who meet national criteria for referral to cardiac rehabilitation, whether entering inpatient or outpatient programs, are eligible to participate.

Probably not a fit

Patients who explicitly refuse participation or who expect a planned hospital readmission within six months after finishing cardiac rehabilitation are not expected to benefit from the registry's findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The ITACARE-P CardioRehab Registry is a nationwide, multicenter observational project coordinated by Fondazione Don Carlo Gnocchi in Milan that enrolls adults with coronary artery disease and/or heart failure who are eligible for cardiac rehabilitation. It gathers standardized clinical, functional, treatment, and program-delivery data from hospitals and rehabilitation centers offering inpatient and outpatient CR. The registry tracks outcomes such as exercise capacity, medication use, readmissions, and quality of life over time to identify which program features and patient subgroups are linked to better recovery. Collected data will be used to describe variation in referral and care pathways and to inform efforts to standardize and improve cardiac rehabilitation services in Italy.

Why it matters

Potential benefit: If successful, the registry could help increase appropriate referrals, standardize rehabilitation programs, and improve recovery and reduce readmissions for patients with coronary disease or heart failure.

How similar studies have gone: Randomized trials and prior registries have shown cardiac rehabilitation improves outcomes and that registries can reveal gaps in delivery, so this observational approach builds on established evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria

Adults (≥18 years) with coronary artery disease and/or heart failure following an acute event, meeting current national regulatory requirements for appropriateness of referral to cardiac rehabilitation (early post-acute referral); Admitted to an inpatient, outpatient, or Complex Outpatient Macro-Activity (MAC) cardiac rehabilitation programme, according to the clinical setting and care pathway; Provision of written informed consent.

Exclusion Criteria

Explicit refusal to participate in the study; Indication for cardiac rehabilitation solely following isolated valvular surgery; Highly unfavourable short-term prognosis (e.g., terminal illness); Planned elective hospital readmission within six months after completion of the cardiac rehabilitation programme.

Where it's running

  • IRCCS Dongnocchi
    Milan, Italy
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.