Evaluating new methods for assessing coronary artery disease after procedures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of using a new method called cFFR-NTG for assessing coronary artery disease in patients with multivessel conditions. It aims to improve the management of intermediate coronary lesions by comparing this method to the traditional fractional flow reserve (FFR) technique, which often requires adenosine. The study will involve patients undergoing percutaneous coronary intervention (PCI) and will utilize a specialized pressure microcatheter for both diagnosis and post-procedure evaluation. By focusing on patients with significant stenosis in multiple vessels, the trial seeks to enhance therapeutic decision-making and patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients \>18 years old and,
* Patients with multivessel coronary artery disease (multivessel coronary artery disease will be considered the presence of significant stenosis in 2 or more first or second order vessels greater than 1.5 mm in diameter with an angiographic reduction of their diameter ≥50% by visual estimation) subsidiary of percutaneous coronary revascularization in at least one of them and,
* Use of Navvus pressure microcatheter both for functional diagnosis and for post-PCI evaluation of the different vessels and,
* Patients who have signed the Informed Consent.

Exclusion Criteria:

* Patients with intolerance or contraindication to adenosine.
* Hemodynamically unstable patients, acute phase of a STEACS.
* Patient with significant comorbidity with limited life expectancy.
* Patients with the patient's express refusal to participate in the study.
* Pregnant or breastfeeding female patients.

Where it's running

• Hospital Universitario San Juan de Alicante
  Alicante, Spain Recruiting
• Hospital Universitario de Badajoz
  Badajoz, Spain Recruiting
• Hospital Universitario Juan Ramón Jiménez
  Huelva, Spain Recruiting
• Hospital Universitario Virgen del Rocío
  Seville, Spain Recruiting

Study contacts

• Study coordinator: SANTIAGO J CAMACHO FREIRE, MD, PhD
• Email: hemodinamica.cardiologia.huelva@gmail.com
• Phone: 0034677981941

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.