Condition
Carpal Tunnel Syndrome (CTS) clinical trials and research
As of November 12, 2026, Find a Trial lists 21 Carpal Tunnel Syndrome (CTS) clinical trials that are recruiting, at sites in 12 countries (most in Turkey (Türkiye) (9), United States (2), Brazil (2)). By phase: Early Phase 1 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 21Clinical trials
- 12Countries
Newest Carpal Tunnel Syndrome (CTS) clinical trials
All recruiting trials (21)
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Ultrasound-Guided Injection for Carpal Tunnel Syndrome: Hyaluronic Acid vs Corticosteroid vs 5% Glucose
This study tests three ultrasound-guided injections (hyaluronic acid, corticosteroid, and 5% glucose) to see which best helps adults with mild to moderate carpal tunnel syndrome.
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Open vs ultrasound-guided carpal tunnel release ( CTS )
This study compares two surgical approaches for carpal tunnel syndrome to see which helps people recover better after surgery.
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Amniotic Membrane and Secretome Added to Carpal Tunnel Release
This trial tests whether adding amniotic membrane and secretome to carpal tunnel surgery helps people with moderate-to-severe CTS recover better than surgery alone.
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Reliability and validity of hand function tests in carpal tunnel syndrome
This study tests whether three hand function tests (JTHFT, MDT, and Nine-Hole Peg Test) are reliable and valid for people with carpal tunnel syndrome.
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Neuromobilization, Tendon Gliding, or Both for Mild to Moderate Carpal Tunnel Syndrome
This trial tests whether neuromobilization, tendon gliding exercises, or a combination of both help reduce pain and improve hand function in people with mild to moderate carpal tunnel syndrome.
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MeDe: Carpal tunnel release with added lacertus release vs carpal tunnel release alone
In adults with carpal tunnel syndrome, this trial tests whether adding a lacertus fibrosus release to the standard carpal tunnel release helps reduce symptoms and improve hand function.
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Effect of peripheral repetitive magnetic stimulation on elbow or wrist pain
This pilot study tests whether two days of active peripheral repetitive magnetic stimulation can reduce pain in adults with tennis/golfer’s elbow or carpal tunnel syndrome, compared with a sham treatment.
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Wrist splint positions for carpal tunnel syndrome
This study tests whether different wrist splint positions help people with carpal tunnel syndrome feel better and move more easily in everyday tasks.
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Local steroid injection in carpal tunnel syndrome with diabetes vs without diabetes
This study tests whether a corticosteroid and lidocaine injection helps people with carpal tunnel syndrome who also have type 2 diabetes as well as those without diabetes.
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Osteopathic manipulation versus wrist immobilization for carpal tunnel syndrome
This test will see if hands-on osteopathic manipulation or wearing a wrist brace works better to reduce pain, numbness, and loss of function in adults with mild to moderate carpal tunnel syndrome.
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Repetitive Peripheral Magnetic Stimulation for Carpal Tunnel Syndrome
This trial tests whether repetitive peripheral magnetic stimulation can help people with mild to moderate carpal tunnel syndrome.
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Rest splints versus high-intensity laser therapy for carpal tunnel syndrome
This project will test whether adding high-intensity laser therapy or using rest splints alongside physical therapy helps people with carpal tunnel syndrome reduce pain and improve hand function.
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Muscle response collapse during the Scratch Collapse Test for carpal tunnel syndrome
We will try to measure the brief, one-sided loss of muscle strength seen during the Scratch Collapse Test in adults with unilateral carpal tunnel syndrome.
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Ultrasound measurements and touch sensation in carpal tunnel syndrome
This study tests whether ultrasound measurements of the median nerve are linked to how much touch sensation people with carpal tunnel syndrome have.
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Paraffin bath versus extracorporeal shock wave therapy: effects on median nerve thickness in carpal tunnel syndrome
This will test if paraffin baths or extracorporeal shock wave therapy better reduce median nerve swelling and relieve numbness and pain in adults aged 30–60 with carpal tunnel syndrome.
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Hand ultrasound and clinical follow-up after carpal tunnel release
This project will try to see if changes in median nerve size on hand ultrasound after open carpal tunnel release match how people's symptoms, sensation, and strength improve over six months.
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Kinesiotaping and peloid (therapeutic mud) therapy for carpal tunnel syndrome
This study will see if adding kinesiotaping or peloid (therapeutic mud) therapy to a home exercise program helps adults with mild to moderate carpal tunnel syndrome reduce pain and improve hand function.
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Comparing corticosteroid injection and nerve hydrodissection for carpal tunnel syndrome
This study is testing whether corticosteroid injections or nerve hydrodissection can help people with carpal tunnel syndrome feel better when combined with exercise therapy.
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Comparing Kaltenborn and Mulligan techniques for treating Carpal Tunnel Syndrome
This study is testing whether two different hands-on therapy techniques can help people with Carpal Tunnel Syndrome feel less pain and improve their hand function.
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Dynavisc to reduce pain after revision carpal tunnel surgery
This study will test whether applying Dynavisc around the median nerve reduces pain in adults who have persistent or recurrent carpal tunnel symptoms after prior surgery.
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Observational study on total wrist replacement outcomes with KinematX implant
This study is testing how well the KinematX wrist replacement helps people regain movement and strength in their wrist after surgery.
Related topics
Quick answers
How many Carpal Tunnel Syndrome (CTS) clinical trials are recruiting right now?
21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 12 countries. The most sites are in Turkey (Türkiye) (9 trials), United States (2 trials), Brazil (2 trials), Pakistan (2 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Early Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.