Condition

Inflammatory Arthritis clinical trials and research

• 11Clinical trials
• 21NIH research projects
• 6Countries

Newest Inflammatory Arthritis clinical trials

All recruiting trials (11)

• Long-term follow-up of FX Shoulder Solutions implants

  This follow-up will track adults who receive FX Shoulder Solutions hemi or total shoulder replacements to see if the implants need revision and how well shoulder function and pain hold up over 10 years.

  Recruiting at 22 sites FX Solutions · Amiens and 21 other locations · NCT07558590

• Palliative and supportive care to help people with inflammatory arthritis live well

  This project will see how palliative and supportive care could help adults with inflammatory arthritis live better throughout their illness.

  Recruiting Dorothy House Hospice · Bath, Wiltshire · NCT07491939

• HbA1c accuracy in people with inflammatory arthritis on sulfasalazine

  This study tests whether HbA1c reliably reflects blood glucose in adults with inflammatory arthritis who are treated with sulfasalazine, by comparing it to continuous glucose monitoring.

  Recruiting Central Jutland Regional Hospital · Silkeborg, Central Jutland · NCT07416656

• Joint tissue analysis to understand rare and immunotherapy-related inflammatory arthritis

  This project tests whether analyzing joint biopsy tissue can reveal distinct immune features in adults with inflammatory arthritis linked to rare autoimmune diseases or caused by cancer immunotherapy.

  Recruiting University Hospital, Brest · Bordeaux and 1 other locations · NCT07302074

• Reducing unnecessary medications in older adults with rheumatic conditions

  This project will test whether giving doctors individualized MedSafer reports plus patient EMPOWER brochures helps people 60+ with rheumatic conditions who take five or more regular medications stop or reduce risky medicines.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07278609

• Legion Medial Stabilized insert in total knee replacement

  This study tests whether the Legion Medial Stabilized insert is safe and works well when used in primary knee replacements for people with osteoarthritis, inflammatory arthritis, or post-traumatic arthritis.

  Recruiting at 3 sites Smith & Nephew, Inc. · Newton, Massachusetts and 3 other locations · NCT07199738

• Self-management intervention for newly diagnosed inflammatory arthritis patients

  This study tests a new self-management program for people recently diagnosed with inflammatory arthritis to see if it helps them feel better and manage their condition more effectively compared to regular care.

  Recruiting at 2 sites Glostrup University Hospital, Copenhagen · Glostrup Municipality and 1 other locations · NCT06533423

• H1 Hip Resurfacing vs Total Hip Replacement in Hip Arthritis

  A randomized trial tests whether a new H1 hip resurfacing can match or beat a cementless ceramic total hip replacement for people with hip arthritis.

  Recruiting at 3 sites Embody Orthopaedic Limited · Bournemouth and 2 other locations · NCT06162195

• Using Adalimumab to treat early inflammatory arthritis caused by immune checkpoint inhibitors

  This study is testing if adalimumab can help people with early inflammatory arthritis caused by cancer treatments to feel better and rely less on steroids.

  Recruiting Phase 2 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT06037811

• Observational study on total wrist replacement outcomes with KinematX implant

  This study is testing how well the KinematX wrist replacement helps people regain movement and strength in their wrist after surgery.

  Recruiting at 4 sites Extremity Medical · Loma Linda, California and 3 other locations · NCT05719935

• Evaluating early inflammatory polyarthritis for better treatment outcomes

  This study is trying to find out if certain blood markers can help doctors identify early on which patients with inflammatory polyarthritis, especially rheumatoid arthritis, might need stronger treatment to avoid severe disease.

  Recruiting Université de Sherbrooke · Sherbrooke, Quebec · NCT00512239

NIH-funded research (21)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding how immune checkpoint drugs can trigger inflammatory arthritis in cancer patients

  This research looks at why some cancer patients develop inflammatory arthritis after PD-1 inhibitor therapy and what could be done to prevent it.

  NIH research Yale University · New Haven, United States · NIH-11603643

• Antenatal DMARD Use and Mother-Child Health in Women with Chronic Inflammatory Arthritis

  This project aims to understand how continuing pregnancy-safe arthritis medicines during pregnancy affects health outcomes for mothers with chronic inflammatory arthritis and their babies.

  NIH research Yale University · New Haven, United States · NIH-11452559

• Gut barrier and antibiotics: how gut health affects inflammatory arthritis

  Antibiotic use may increase the risk of inflammatory arthritis by changing the gut, and this project looks at how those gut changes influence joint inflammation in people with arthritis.

  NIH research Washington University · Saint Louis, United States · NIH-11417167

• ctDNA biomarker to guide safety of cancer immunotherapy in inflammatory arthritis

  A patient-facing biomarker study using a blood test to detect tumor DNA in people with cancer who develop inflammatory arthritis from immunotherapy, to help doctors pick safer treatment choices.

  NIH research Hospital for Special Surgery · New York, UNITED STATES · NIH-11411495

• Setbp1’s role in how joint cells behave during inflammatory arthritis

  This project looks at how a protein called SETBP1 affects delicate joint cells (FLS) that drive inflammation in arthritis, with potential implications for better treatments.

  NIH research Emory University · Atlanta, United States · NIH-11398188

• Bacteria-made indoles and inflammatory arthritis

  A study from the University of Colorado Denver is looking at how gut bacteria convert tryptophan into indoles that may drive inflammatory arthritis in people.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11380536

• Understanding immune-triggered inflammatory arthritis from cancer immunotherapy

  A clinical study looks at why inflammatory arthritis caused by cancer immunotherapy affects people differently and how to best treat it.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11365141

• How B cells and other immune cells drive psoriatic arthritis

  This project explores how certain immune B cells and other immune cells cause inflammation and joint damage in people with psoriatic arthritis.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11319902

• Helping bones heal in rheumatoid arthritis

  This project uses a bone-targeted gene therapy to turn off a protein that blocks bone growth, aiming to help people with rheumatoid arthritis rebuild bone.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11286838

• Understanding severe inflammatory arthritis from silica exposure

  This research explores how breathing in silica dust might lead to severe inflammatory arthritis, like rheumatoid arthritis, by studying it in a new way.

  NIH research Scripps Research Institute, the · La Jolla, United States · NIH-11170433

• How gut bacteria breaking down tryptophan may drive inflammatory arthritis

  This project looks at whether gut bacteria that convert the amino acid tryptophan into indole compounds promote inflammation in people with rheumatoid arthritis and spondyloarthritis.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11166419

• How SETBP1 changes joint‑lining cells in inflammatory arthritis

  This project explores how the protein SETBP1 alters joint‑lining cells in people with inflammatory arthritis to point toward new treatment strategies.

  NIH research Emory University · Atlanta, United States · NIH-11163524

• Understanding how immune cells contribute to inflammatory arthritis

  This study is looking at how certain immune cells, especially B cells, affect the inflammation and joint damage in people with psoriatic arthritis, using a special mouse model to help find better treatments that could improve your health.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11072806

• New methods to help bones heal in people with inflammatory arthritis

  This study is looking for new ways to help people with rheumatoid arthritis heal their bones better by blocking a protein that stops bone growth, and it aims to see if this treatment can improve bone health for those affected by the condition.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11042707

• Investigating the role of IL-23 in inflammatory arthritis

  This study is looking at how a protein called IL-23 affects inflammatory arthritis, which many people have, to find new ways to treat the condition and help patients feel better.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11000864

• Understanding how silica exposure can lead to severe inflammatory arthritis

  This study is looking at how being around silica dust at work might lead to serious joint inflammation and autoimmune diseases, especially for people in mining jobs, by using a mouse model to see how the body reacts to this exposure.

  NIH research Scripps Research Institute, the · La Jolla, United States · NIH-10989496

• How bacteria break down tryptophan affects inflammatory arthritis

  This study is looking at how the bacteria in our gut break down a substance called tryptophan and how this process might affect the development of inflammatory arthritis, like rheumatoid arthritis and spondyloarthritis, so if you're a patient, your samples could help us understand this connection better!

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10979436

• Understanding how gut health affects inflammatory arthritis

  This study is looking at how the health of your gut affects inflammatory arthritis, especially how antibiotics might change your gut bacteria and increase joint inflammation, and it hopes to find out if adding certain fatty acids back into your diet can help ease arthritis symptoms.

  NIH research Washington University · Saint Louis, United States · NIH-10950024

• Understanding immune changes in arthritis caused by cancer treatments

  This study is looking at how a cancer treatment called immune checkpoint inhibitors might cause joint pain and inflammation in some patients, and it aims to understand how the immune system, especially certain immune cells, is involved in this process to help improve care for those affected.

  NIH research Yale University · New Haven, United States · NIH-10892882

• How inflammation from arthritis may lead to heart disease

  This study is looking at how long-term inflammation from rheumatoid arthritis might make certain immune cells more active, which could increase the risk of heart problems for people with RA, and it aims to find new ways to help manage these risks.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10870309

• Investigating arthritis caused by cancer immunotherapy

  This study is looking at how some cancer treatments can cause joint pain and swelling in certain patients, and it aims to find out what makes some people more likely to experience this so we can improve care for those affected.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10680524

Related topics

Quick answers

How many Inflammatory Arthritis clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in Canada (3 trials), United Kingdom (2 trials), France (2 trials), United States (2 trials), Denmark (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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