Comparing corticosteroid injection and nerve hydrodissection for carpal tunnel syndrome
Comparison of the Efficacy of Corticosteroid Injection and Saline Nerve Hydrodissection on Electrophysiological Study, Pain, Function and Sonographic Findings in the Treatment of Carpal Tunnel Syndrome: A Randomized Controlled Trial
This study is testing whether corticosteroid injections or nerve hydrodissection can help people with carpal tunnel syndrome feel better when combined with exercise therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Kirsehir Ahi Evran Universitesi Academic / other |
| Locations | 2 sites (Kırşehir, City Centre and 1 other locations) |
| Trial ID | NCT06882603 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of corticosteroid injections and nerve hydrodissection in treating carpal tunnel syndrome (CTS) by comparing their benefits alongside exercise therapy. Participants diagnosed with CTS will receive either treatment and their symptoms, including pain and numbness, will be monitored. The study seeks to determine which method provides better relief for patients suffering from this common nerve compression condition. The research will involve a thorough assessment of patient responses to the interventions over a specified period.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 diagnosed with carpal tunnel syndrome who can provide informed consent.
Not a fit: Patients with conditions such as cervical radiculopathy, systemic diseases, or those who have previously undergone carpal tunnel surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective treatment options for patients suffering from carpal tunnel syndrome.
How similar studies have performed: Previous studies have shown varying degrees of success with corticosteroid injections for CTS, but the combination with nerve hydrodissection is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Female and male patients aged 18-65 who applied to Ahi Evran University Physical Medicine and Rehabilitation Polyclinic and diagnosed with carpal tunnel syndrome through clinical and EMG 2. Patients who can understand the information form correctly and are cooperative 3. Patients who consented to participate in the study according to the informed consent form Exclusion Criteria: 1. Cervical radiculopathy 2. Polyneuropathy 3. Brachial plexopathy 4. Systemic corticosteroid use 5. History of fracture and trauma in the forearm and wrist on the treated side 6- Inflammatory rheumatic disease 7- Pregnant and breastfeeding patients 8- Systemic diseases such as renal failure, peptic ulcer, diabetes, hypothyroidism, coagulation disorders 9- Patients who have undergone carpal tunnel syndrome surgery 10- Thoracic outlet syndrome 11- Thenar atrophy, severe carpal tunnel syndrome 12- Patient is unwilling or states that they cannot participate for any reason
Where this trial is running
Kırşehir, City Centre and 1 other locations
- Ahi Evran University — Kırşehir, City Centre, Turkey (Türkiye) (Recruiting)
- Ahi Evran University — Kırşehir, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Basak Cigdem Karacay, Assoc. Prof — Kirsehir Ahi Evran Universitesi
- Study coordinator: Basak Cigdem Karacay, Assoc. Prof.
- Email: basakcigdem@hotmail.com
- Phone: +905445094803
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.