Repetitive Peripheral Magnetic Stimulation for Carpal Tunnel Syndrome
Official title: The Effects of Repetitive Peripheral Magnetic Stimulation on Clinical and Electrophysiological Parameters in Patients With Carpal Tunnel Syndrome: A Double-Blind, Randomized, Sham-Controlled Trial
Run by Ankara University · NCT07327723 · Data updated 2026-11-12
This trial tests whether repetitive peripheral magnetic stimulation can help people with mild to moderate carpal tunnel syndrome.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Ankara University Academic / other |
| Locations | 1 site (Ankara, Mamak) |
| Status | Recruiting |
| Started | January 1, 2026 |
| Main results expected | December 15, 2026 |
| Study ends | January 15, 2027 |
| Registry record updated | November 3, 2026 |
| Trial ID | NCT07327723 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with clinically and electrodiagnostically confirmed mild to moderate CTS.
✕Probably not a fit
Individuals with severe CTS, prior CTS surgery, recent CTS interventions, or conditions mimicking CTS may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective, randomized, sham-controlled, double-blind study compares active repetitive peripheral magnetic stimulation (rPMS) plus tendon and nerve gliding exercises to sham rPMS plus the same exercises in adults with mild to moderate CTS. Participants receive six 10-minute rPMS sessions over three weeks, with outcomes assessed at baseline, three weeks after treatment, and six weeks post-treatment. The study uses electrodiagnostic confirmation of CTS and is conducted at Ankara University; a blinded physiotherapist administers the intervention. Safety and tolerability are monitored throughout the treatment period.
Why it matters
Potential benefit: If successful, rPMS could offer a non-invasive option to improve symptoms and function in CTS.
How similar studies have gone: This approach is relatively novel for CTS, with limited prior evidence in this exact modality but builds on magnet-related neuromodulation concepts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria * Voluntary participation with signed informed consent * Presence of symptoms consistent with carpal tunnel syndrome (CTS) (pain and/or paresthesia in the median nerve distribution), clinical signs (i.e., positive Tinel's and/or Phalen's test results), and electrodiagnostic findings (demonstrating mild to moderate CTS based on sensory or motor conduction studies of the median nerve) Exclusion Criteria: * Electrodiagnostic evidence of severe CTS * Abnormal ulnar nerve conduction findings * History of surgery for CTS * History of physical therapy or injection for CTS within the past 6 months * History of wrist fracture * Presence of other conditions causing similar symptoms, such as polyneuropathy, cervical radiculopathy, ulnar neuropathy, brachial plexopathy, or thoracic outlet syndrome * Central nervous system disorders (e.g., stroke, multiple sclerosis, Parkinson's disease) * Pregnancy * Presence of risk factors for CTS such as rheumatologic diseases, chronic kidney disease, diabetes mellitus, or hypothyroidism * Malignancy * Contraindications to rPMS (e.g., pacemaker, cochlear implant)
Where it's running
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Ankara University, Faculty of Medicine, Cebeci Hospital, Cebeci
Ankara, Mamak, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Seçilay Güneş, Associated Professor
- Email: yalices@hotmail.com
- Phone: +905325562057
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.