Ultrasound measurements and touch sensation in carpal tunnel syndrome
Investigation of the Relationship Between Ultrasonographic Parameters and Tactile Sensation in Carpal Tunnel Syndrome
This study tests whether ultrasound measurements of the median nerve are linked to how much touch sensation people with carpal tunnel syndrome have.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 84 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Academic / other |
| Locations | 1 site (Üsküdar, İ̇stanbul) |
| Trial ID | NCT07170449 on ClinicalTrials.gov |
What this trial studies
This observational, single-center study enrolls adults with electrodiagnostically confirmed carpal tunnel syndrome and compares median nerve ultrasonography measurements with standardized sensory testing and nerve conduction studies. Investigators exclude participants with diabetes, systemic inflammatory disease, other neuropathies, prior CTS surgery, or advanced hand arthritis to avoid confounding conditions. Sonographic indices such as nerve cross-sectional diameter at the tunnel inlet and outlet are recorded and correlated with patients' tactile complaints and sensory test results. The goal is to clarify whether specific ultrasound parameters track with sensory loss in CTS.
Who should consider this trial
Good fit: Adults aged 18–65 with electrodiagnostically confirmed carpal tunnel syndrome who have sensory symptoms for at least six weeks and can read and consent are the ideal candidates.
Not a fit: People with diabetes, systemic inflammatory disease, other neuropathies (like polyneuropathy or radiculopathy), prior carpal tunnel surgery, advanced hand arthritis, or those outside the 18–65 age range are unlikely to benefit from this study's specific findings.
Why it matters
Potential benefit: If successful, this could help clinicians use ultrasound measurements to better understand or monitor sensory loss in CTS and guide diagnosis or treatment decisions.
How similar studies have performed: Previous research shows ultrasound can detect median nerve enlargement and sometimes correlates with nerve conduction findings, but relationships specifically between sonographic indices and tactile sensation have been inconsistent.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Electrodiagnostic diagnosis of carpal tunnel syndrome with pain, numbness, burning, and tingling consistent with the median nerve dermatomal area lasting at least 6 weeks. * Literate * Agree to participate in the study Exclusion Criteria: * Concomitant diabetes, systemic inflammatory disease, active infection, and history of malignancy * Being \<18 and \>65 years old * Being illiterate * Refusing to participate in the study * Having a disease with neuropathic pain, such as polyneuropathy, radiculopathy, or MS * Other concomitant upper extremity entrapment neuropathies (e.g., cubital tunnel syndrome) * Having undergone surgery for carpal tunnel syndrome * Rheumatoid arthritis, advanced hand osteoarthritis
Where this trial is running
Üsküdar, İ̇stanbul
- Sultan Abdülhamit Han Trainin and Educational Hospital — Üsküdar, İ̇stanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Müyesser Cavlak, PhD — Sultan Abdülhamit Han Trainin and Educatioal Hospital
- Study coordinator: Müyesser Cavlak, PhD
- Email: muyessercavlak@hotmail.com
- Phone: +905426406118
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.