Wrist splint positions for carpal tunnel syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares three wrist splint positions—flexion, neutral, and extension—along with education and an exercise program for adults with mild to moderate carpal tunnel syndrome. Eligible participants are ages 18 to 65 and have recent electrophysiology-confirmed CTS with typical symptoms. The goal is to determine which combination of splint position and activity provides the best relief and functional improvement while avoiding progression requiring surgery. Outcomes likely include symptom severity, functional ability, and safety measures over a defined follow-up period. The study may inform non-surgical management of CTS by tailoring splinting strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of mild to moderate carpal tunnel syndrome confirmed by electrophysiological studies performed within the last year.
* Clinical findings consistent with carpal tunnel syndrome.
* Age between 18 and 65 years.

Exclusion Criteria:

* \<18 years or \>65 years
* Thenar atrophy
* Surgery history for CTS
* Steroid injection for CTS
* Physical treatment for CTS in the last 6 months
* Cervical radiculopathy
* Tenosynovitis
* Peripheral polyneuropathy
* Another compressive neuropathy in the ipsilateral upper extremity
* History of trauma/fracture to the hand-wrist region
* Pregnancy
* Metabolic disease
* Rheumatic/autoimmune disease
* Kidney failure

Where it's running

• Istanbul University
  Istanbul, Turkey (Türkiye) Recruiting

Similar studies

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.