Sedation with dexmedetomidine, propofol, or both during cataract surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, randomized, single-blind trial that enrolls adults undergoing elective cataract surgery and assigns them to one of three sedation protocols: dexmedetomidine plus fentanyl, propofol plus fentanyl, or a combination of dexmedetomidine and propofol with fentanyl. Dosing includes a dexmedetomidine loading dose (0.5 µg/kg over 10 minutes) with maintenance infusion, target-controlled propofol to reach Ramsay Sedation Score 2–3, and a single fentanyl bolus (1 µg/kg) in all groups. Patients are continuously monitored intraoperatively for sedation level, heart rate, blood pressure, and respiratory events, and outcomes include surgeon satisfaction and adverse events such as bradycardia, hypotension, nausea, and respiratory complications. The study compares efficacy and safety across the three protocols to identify whether one approach offers superior balance of comfort and physiologic stability.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults undergoing cataract surgery

Exclusion Criteria:

* Severe hepatic insufficiency
* Third degree AV block
* Patient refusal

Where it's running

• Hotel-Dieu de France
  Beirut, Lebanon Recruiting

Study contacts

• Study coordinator: Rhea Nacouzi, MD
• Email: rhea.nacouzi@net.usj.edu.lb
• Phone: +961 3359528

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.