Clinical trial Recruiting at 1 site Observational Ages 1 Month to 100

Monitoring heart rate changes during eye muscle surgery

Official title: The Alaska Oculocardiac Reflex Study

Run by Alaska Blind Child Discovery · NCT04353960 · Data updated 2026-11-12

This study is testing how eye muscle surgery affects heart rate in patients to better understand their body's response during the procedure.

Quick facts

Study typeObservational
Ages1 Month to 100 Years
SexAll
Enrollment4000 (estimated)
SponsorAlaska Blind Child Discovery
Academic / other
Locations1 site (Anchorage, Alaska)
StatusRecruiting
StartedSeptember 1, 1992
Main results expectedDecember 31, 2035
Study endsDecember 31, 2035
Registry record updatedJuly 31, 2024
Trial IDNCT04353960 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients scheduled for ocular manipulation and strabismus surgery.

Probably not a fit

Patients with anophthalmia will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients undergoing strabismus surgery, where vital signs and anesthetic variables, particularly heart rate, will be monitored. The study aims to observe the oculocardiac reflex (OCR) by applying uniform tension on extra ocular muscles during the procedure. Data collected will include demographic information and various peri-operative variables to assess the impact of ocular manipulation on heart rate. The study seeks to enhance understanding of the physiological responses during eye surgeries.

Why it matters

Potential benefit: If successful, this study could improve patient safety and outcomes during strabismus surgery by better understanding heart rate responses.

How similar studies have gone: While the specific approach may be novel, studies on the oculocardiac reflex have been conducted, indicating potential for valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient scheduled for ocular manipulation and tension on extra ocular muscles and strabismus surgery

Exclusion Criteria:

* anophthalmia

Where it's running

  • Alaska Children's EYE & Strabismus
    Anchorage, Alaska, United States
    Recruiting

Study contacts

  • Principal investigator: Robert W Arnold, MD — Alaska Blind Child Discovery
  • Study coordinator: Robert W Arnold, MD
  • Email: eyedoc@alaska.net
  • Phone: 907-242-6180

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.