Monitoring heart rate changes during eye muscle surgery

The Alaska Oculocardiac Reflex Study

Alaska Blind Child Discovery · NCT04353960

This study is testing how eye muscle surgery affects heart rate in patients to better understand their body's response during the procedure.

Quick facts

Study typeObservational
Enrollment4000 (estimated)
Ages1 Month to 100 Years
SexAll
SponsorAlaska Blind Child Discovery (other)
Locations1 site (Anchorage, Alaska)
Trial IDNCT04353960 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients undergoing strabismus surgery, where vital signs and anesthetic variables, particularly heart rate, will be monitored. The study aims to observe the oculocardiac reflex (OCR) by applying uniform tension on extra ocular muscles during the procedure. Data collected will include demographic information and various peri-operative variables to assess the impact of ocular manipulation on heart rate. The study seeks to enhance understanding of the physiological responses during eye surgeries.

Who should consider this trial

Good fit: Ideal candidates are patients scheduled for ocular manipulation and strabismus surgery.

Not a fit: Patients with anophthalmia will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve patient safety and outcomes during strabismus surgery by better understanding heart rate responses.

How similar studies have performed: While the specific approach may be novel, studies on the oculocardiac reflex have been conducted, indicating potential for valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient scheduled for ocular manipulation and tension on extra ocular muscles and strabismus surgery

Exclusion Criteria:

* anophthalmia

Where this trial is running

Anchorage, Alaska

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Bradycardia, Strabismus, oculocardiac reflex

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.