Evaluating His Bundle Pacing for Heart Conditions
His Bundle Pacing in Bradycardia and Heart Failure
This study is testing if special pacing techniques during pacemaker implantation can help improve heart function in people with heart failure or slow heart rates.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT03008291 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients with heart failure or bradycardia who are scheduled for pacemaker implantation. Participants will undergo procedures such as His bundle pacing or left bundle area pacing, and additional heart rhythm measurements will be collected during the implantation to assess the effects on electrical conduction. The study aims to understand how these pacing techniques can normalize atrioventricular conduction in patients with heart failure or AV block.
Who should consider this trial
Good fit: Ideal candidates include patients with heart failure scheduled for pacemaker implantation or those with AV block or bradycardia recommended for dual chamber pacemaker implantation.
Not a fit: Patients under 18 years old or pregnant women will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pacing techniques that enhance heart function and patient outcomes in those with heart failure and bradycardia.
How similar studies have performed: Other studies have shown promising results with similar pacing approaches, indicating potential for success in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: HF Group * Clinically recommended to undergo PM, CRT-P, or CRT-D implantation or HIBP/LBAP (including HIBP/LBAP for patients with HF, for patients who have failed CRT implant or patients who are CRT non-responders) * Any QRS duration * LVEF ≤ 50% AV Block/Bradycardia Group * Recommended to undergo dual chamber pacemaker implantation * Any AV block or Sinus Bradycardia Exclusion Criteria: * Age \< 18 years * Pregnant
Where this trial is running
Rochester, Minnesota
- Mayo Clinic — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Yong-Mei Cha, M.D. — Mayo Clinic
- Study coordinator: Yong-Mei Cha, M.D.
- Email: ycha@mayo.edu
- Phone: (507) 255-2440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.