Improving chest compressions for newborns with low heart rates during resuscitation

Optimizing Chest Compressions for Bradycardia during Neonatal Resuscitation

NIH-funded research State University of New York at Buffalo · NIH-11158673

This study is looking at the best way to give chest compressions to newborns with slow heart rates during resuscitation, to help improve their chances of survival and protect their brains.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo NIH-funded
Lab location1 site (Amherst, United States)
Project IDNIH-11158673 on NIH RePORTER

What this research studies

This research investigates how to optimize chest compressions for newborns experiencing bradycardia during resuscitation. It aims to determine the most effective heart rate threshold for initiating compressions, focusing on improving blood flow to the brain and heart. By using animal models, the study will evaluate the impact of different heart rate ranges on gas exchange and overall outcomes. The goal is to refine current neonatal resuscitation protocols to enhance survival and reduce brain injury in newborns.

Who could benefit from this research

Good fit: Ideal candidates for this research are newborns experiencing bradycardia during resuscitation efforts.

Not a fit: Patients who are not newborns or who do not experience bradycardia during resuscitation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved survival rates and reduced brain injury in newborns who experience low heart rates during resuscitation.

How similar studies have performed: Previous research has indicated that optimizing resuscitation techniques can significantly improve outcomes in neonatal care, suggesting potential success for this approach.

Where this research is happening

Amherst, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.