NIH-funded research R01 grant

Improving chest compressions for newborns with low heart rates during resuscitation

Official title: Optimizing Chest Compressions for Bradycardia during Neonatal Resuscitation

Funded at State University of New York at Buffalo · NIH-11158673 · Data updated 2026-11-12

This study is looking at the best way to give chest compressions to newborns with slow heart rates during resuscitation, to help improve their chances of survival and protect their brains.

More Bradycardia research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo
NIH-funded
Lab location1 site (Amherst, United States)
Project startMay 1, 2021
Project endApril 30, 2026
Funding year2025
Award (this year)$305,303
NIH project number5R01HD104909-05
Project IDNIH-11158673 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are newborns experiencing bradycardia during resuscitation efforts.

Less likely to help

Patients who are not newborns or who do not experience bradycardia during resuscitation may not benefit from this research.

What this research studies

This research investigates how to optimize chest compressions for newborns experiencing bradycardia during resuscitation. It aims to determine the most effective heart rate threshold for initiating compressions, focusing on improving blood flow to the brain and heart. By using animal models, the study will evaluate the impact of different heart rate ranges on gas exchange and overall outcomes. The goal is to refine current neonatal resuscitation protocols to enhance survival and reduce brain injury in newborns.

Why it matters

Potential benefit: If successful, this research could lead to improved survival rates and reduced brain injury in newborns who experience low heart rates during resuscitation.

How similar studies have gone: Previous research has indicated that optimizing resuscitation techniques can significantly improve outcomes in neonatal care, suggesting potential success for this approach.

Where this research is happening

  • State University of New York at Buffalo
    Amherst, United States
    Active

Researchers

  • Principal investigator: Chandrasekharan, Praveen — State University of New York at Buffalo
  • Study coordinator: Chandrasekharan, Praveen

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.