New care guideline for infants 60 days and younger with fever in Sweden

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational implementation across 11 pediatric emergency departments in Sweden. Seven sites will introduce a new clinical guideline for fever without source in infants ≤60 days, while four sites will continue standard practice to provide a comparison. All febrile infants aged ≤60 days presenting with temperature ≥38.0°C are eligible and will be followed for diagnostic testing, hospital admissions, antibiotic use, and missed invasive bacterial infections. The design aims to measure real-world safety, resource use, and potential reductions in unnecessary care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Temperature ≥38.0 C (measured either at home or at the pediatric emergency department)
* Age ≤60 days

Where it's running

• Sahlgrenska University Hospital
  Gothenburg, Sweden Recruiting
• Ryhov County Hospital
  Jönköping, Sweden Recruiting
• Kristianstad Central Hospital
  Kristianstad, Sweden Recruiting
• Skåne University Hospital
  Lund, Sweden Recruiting
• Skåne University Hospital
  Malmö, Sweden Recruiting
• Örebro University Hospital
  Örebro, Sweden Recruiting

Study contacts

• Study coordinator: Ioannis Orfanos, Senior Consultant
• Email: ioannis.orfanos@med.lu.se
• Phone: +4646178225

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.