Examining biofilm in arterial catheters in ICU patients
Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography
This study looks at the germs that build up on arterial catheters in ICU patients to see how they might cause infections and find better ways to prevent them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier William Morey - Chalon sur Saône Academic / other |
| Locations | 2 sites (Dijon, Bourgogne-Franche-Comté and 1 other locations) |
| Trial ID | NCT06838598 on ClinicalTrials.gov |
What this trial studies
This observational study aims to characterize the structural and microbiological aspects of biofilm that forms on arterial catheters used in ICU patients. By utilizing optical coherence tomography, the researchers will gather data to understand the relationship between biofilm formation and the incidence of bacteremias associated with these vascular devices. The goal is to provide insights that could lead to improved prevention strategies or targeted treatments for infections related to arterial catheters.
Who should consider this trial
Good fit: Ideal candidates for this study are ICU patients over 18 years old who have an arterial catheter in place.
Not a fit: Patients who are unable to provide consent or have had their arterial catheter removed outside of standard procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better prevention and treatment strategies for bacteremias in ICU patients.
How similar studies have performed: While the approach of using optical coherence tomography for biofilm characterization is innovative, there is limited clinical data documenting its success in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient or relative informed of the study and having declared their non-objection * Patient over 18 years old * Patient hospitalized in ICU with an arterial catheter Exclusion Criteria: * Patient unable to express consent * Patient whose collection of the arterial catheter is impossible or for whom storage at 4°C is impossible * Patient with arterial catheter removed outside the usual procedure of the ICU * Patient admitted in ICU with an arterial catheter already in place
Where this trial is running
Dijon, Bourgogne-Franche-Comté and 1 other locations
- CHU Dijon Bourgogne — Dijon, Bourgogne-Franche-Comté, France (Recruiting)
- CH Macon — Mâcon, Bourgogne-Franche-Comté, France (Recruiting)
Study contacts
- Study coordinator: Florian PERRAUD
- Email: florian.perraud@ch-chalon.fr
- Phone: 06 78 58 85 19
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.