Sponsor or institution
Clinical trials and research at University of South Alabama
As of November 12, 2026, Find a Trial lists 2 clinical trials run by University of South Alabama that are recruiting, in United States. By phase: Phase 2 (1). There are also 43 NIH-funded research projects at this institution, with $18.7 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 2Clinical trials
- 43NIH research projects
- 1Country
All recruiting trials (2)
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MRI-guided low-voltage brain stimulation for depression in Parkinson's disease
This tests whether MRI-guided low-voltage transcranial direct current stimulation (mgTDCS) can reduce depression and apathy and improve working memory in adults with Parkinson's disease.
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Using rhDNase to reduce mortality in COVID-19 patients with respiratory failure
This study is testing if a new inhaled treatment called rhDNase can help reduce the risk of death in adults with severe COVID-19 who need extra oxygen or a ventilator.
NIH-funded research (newest 40 of 43)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Nanobody tools to study NEIL1 and NEIL2 in DNA repair
A small, targeted grant will create special nanobodies to study how NEIL1 and NEIL2 repair damaged DNA in human cells and mitochondria.
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Nosocomial pneumonias and cognitive function in ICU survivors
In ICU survivors, this project looks at how pneumonia acquired in the hospital may be linked to long-term thinking and memory problems.
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Mesenchymal cells to protect lungs by moving mitochondria to repair blood vessel function
Aims to test whether intravenously given mesenchymal stromal cells can help people with acute lung injury by transferring mitochondria to lung cells and restoring their barrier function.
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Pathogen-linked amyloid-β and kidney inflammation in UTIs
A small NIH grant is exploring whether amyloid-β, a protein better known for its role in dementia, helps fight urinary tract infections but may also drive kidney inflammation.
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Cell-free hemoglobin and oxLDL: a pathway to lung inflammation in sepsis
This program looks at how free hemoglobin in the blood and oxidized LDL may break down the lung’s blood vessel barrier during sepsis, potentially leading to ARDS.
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Mitochondria moving between nerves and breast cancer cells
A study to understand how nerve cells and breast cancer cells exchange mitochondria and how this affects cancer spread, with a focus on triple-negative breast cancer.
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Lung infections and brain health: could lung-made tau affect thinking after critical illness
A government-funded study will look at whether a protein variant released from the lungs during pneumonia could contribute to thinking and memory problems after serious illness.
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Understanding how a tick-borne virus spreads inside ticks and into people
Researchers are studying how SFTS virus travels and multiplies inside ticks and in the early moments of infection in people, aiming to prevent the virus from spreading.
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How low oxygen changes genes in lung disease
This project looks at how low oxygen in lung disease changes gene activity to uncover targets for future treatments.
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Molecular control of blood pressure by progranulin in blood vessel cells
A study to understand how progranulin helps blood vessels stay healthy and keep blood pressure normal, with insights that could lead to new treatments for hypertension.
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How the Lyme bacteria get into the brain and spinal cord
Researchers will learn how the Lyme disease bacterium Borrelia burgdorferi enters the brain and spinal fluid using mouse models to help people with neurologic Lyme disease.
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Soluble adenylyl cyclases and lung endothelium health after infection
A patient-friendly look at a research effort to understand how a common lung infection can damage the blood vessels in the lungs and how this damage could be reduced.
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How mitochondrial DNA affects lung inflammation and healing
Looking at whether damaged mitochondrial DNA drives lung inflammation and whether fixing that DNA can help lungs recover after acute injury.
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How low blood pH (acidosis) affects lung blood vessel injury and healing
This work looks at whether low blood pH during severe pneumonia causes harmful protein release that damages tiny lung blood vessels and whether targeting a protein called CA IX could help people with pneumonia.
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Why some gonorrhea strains resist ceftriaxone antibiotics
Researchers are working to understand how changes in a bacterial protein make gonorrhea resistant to ceftriaxone, to help people with drug-resistant infections.
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Developing models to understand infectious diseases.
This study is all about building models that mimic infectious diseases so researchers can learn how they work and find better treatments, which could help patients like you in the future.
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How a protein called progranulin affects blood vessel function and blood pressure
This study is looking at how a protein called progranulin helps keep blood vessels healthy and how not having enough of it might lead to high blood pressure, with the hope of finding new ways to treat hypertension and improve heart health for patients.
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Hospital-acquired pneumonia and long-term thinking problems
This project looks at whether bacterial pneumonia picked up in the hospital leads to toxic protein fragments that can harm thinking and memory in ICU survivors.
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How fleas spread emerging Rickettsia infections
This project looks at how fleas carry and pass on Rickettsia bacteria that can make people sick, especially for people and pets in areas where these infections occur.
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Understanding how blood components cause lung damage in sepsis
This research aims to understand how certain substances in the blood contribute to severe lung injury in patients with sepsis.
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How Airway Cells Manage Signals for Better Breathing
This project looks at how cells in your airways organize their internal signals to help your breathing muscles work their best.
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Using mitochondrial DNA to improve early detection and predict recurrence of triple-negative breast cancer in African American women
This study is looking at how tiny pieces of DNA from your cells can help find triple-negative breast cancer earlier and predict if it might come back, especially for African American women, so that doctors can offer better screenings and personalized treatments.
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Investigating how cell-free hemoglobin affects lung injury during sepsis
This study is looking at how a substance called cell-free hemoglobin can harm the lungs in people with sepsis, which might help us find new ways to treat lung problems like ARDS.
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Understanding how a tick-borne virus spreads in ticks and people
This project looks at how a serious tick-borne virus, SFTSV, moves between ticks and people to help us find ways to stop its spread.
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Understanding how Lyme disease bacteria invade the nervous system
This study is looking at how the bacteria that cause Lyme disease can enter the brain and spinal fluid, and how different types of mice respond to this infection, to help find better treatments for people with serious neurological issues related to Lyme disease.
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How pneumonia affects the brain's blood vessels
This study is looking at how pneumonia can affect the brain and memory in people who have survived the infection, with the goal of finding ways to help prevent thinking problems later on.
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How pneumonia affects brain health and may lead to dementia
This study is looking at how pneumonia, especially from a specific germ called Pseudomonas aeruginosa, might affect brain health and lead to dementia, using mice to see how infections can change brain function over time.
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Investigating how mitochondrial DNA affects lung inflammation and recovery
This study is looking at how tiny pieces of DNA from our cells' energy factories, called mitochondria, affect lung diseases by influencing inflammation and healing, with the hope of finding new ways to help people recover from these conditions.
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How inositol phosphate affects aging through nutrient signaling
This study is looking at how a natural substance called IP6 might help slow down aging by affecting a specific cell signaling pathway, especially when there's too much sugar around, and it hopes to find ways to improve health and longevity for everyone.
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Investigating how lung infections affect cell signaling and injury repair
This study is looking at how a specific enzyme in the lungs helps respond to infections like those caused by Pseudomonas aeruginosa, which can hurt lung function, and it hopes to find new ways to help people recover better from these infections.
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Understanding how Neisseria gonorrhoeae becomes resistant to antibiotics
This study is looking at how certain changes in a protein in the gonorrhea bacteria help it resist antibiotics, with the goal of finding better treatments for people with gonorrhea.
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Understanding how low oxygen levels affect gene expression in lung diseases
This study is looking at how low oxygen levels in the body affect genes related to lung diseases, with the hope of finding new ways to understand and treat these conditions better.
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Understanding how acidosis affects lung injury in pneumonia patients
This study is looking at how a condition called acidosis affects pneumonia and the tiny blood vessels in the lungs, with the hope of finding better ways to diagnose and treat patients who are seriously ill with pneumonia.
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Investigating how a bacterial factor causes cell death in lung cells
This study is looking at how a germ called Pseudomonas aeruginosa uses a special factor to cause lung cells to die in a way that can lead to serious lung problems, especially in older adults, and aims to find out more about how this happens to help improve treatments.
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How hospital-acquired pneumonia affects brain function
This study is looking at how pneumonia that you might get while in the hospital can affect your thinking and memory, especially if you've been in intensive care, by checking for harmful substances in your blood and spinal fluid.
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Bacterial pneumonia in ICU patients affects brain function.
This study is looking at how getting bacterial pneumonia while in intensive care might affect your thinking and memory later on, and it’s for patients who have survived that experience.
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Investigating how a protein related to Alzheimer's may protect the lungs from injury
This study is looking at how a protein called APP helps protect the lungs during infections, especially from a bacteria that can cause serious problems, and it’s for anyone interested in understanding how our immune system works and how we might improve treatments for lung injuries.
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Understanding how low blood flow affects blood vessel function
This study is looking at how low blood flow affects the inner lining of blood vessels and aims to find new ways to help people with conditions like peripheral artery disease by understanding the signals that keep blood vessels healthy.
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Understanding how a tick-borne virus spreads and infects hosts
This study is looking into how the SFTS virus spreads through ticks and affects people, with the goal of finding new ways to prevent this illness that’s becoming more common.
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Understanding how airway cells control signaling for better function
This study is looking at how certain cells in the airways work with signals inside them to help control their actions, which is important for conditions like asthma, and it hopes to find new ways to improve treatments for patients.
Quick answers
How many clinical trials run by University of South Alabama are recruiting right now?
2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.