NIH-funded research R01 grant

Understanding how a tick-borne virus spreads and infects hosts

Official title: Intra-tick and intra-host infection dynamics of a tick-borne bunyavirus

Funded at University of South Alabama · NIH-10867529 · Data updated 2026-11-12

This study is looking into how the SFTS virus spreads through ticks and affects people, with the goal of finding new ways to prevent this illness that’s becoming more common.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of South Alabama
NIH-funded
Lab location1 site (Mobile, United States)
Project startJuly 1, 2022
Project endJune 30, 2027
Funding year2024
Award (this year)$524,351
NIH project number5R01AI171398-03
Project IDNIH-10867529 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living in or traveling to areas where SFTS is prevalent, particularly in East Asia.

Less likely to help

Patients who do not reside in or travel to regions affected by SFTS may not benefit from this research.

What this research studies

This research investigates the dynamics of the SFTS virus, which is transmitted by the Haemaphysalis longicornis tick. It aims to understand how the virus replicates and survives in both ticks and vertebrate hosts, focusing on the infection process and transmission timeline. By studying these interactions, the research seeks to uncover critical information that could lead to new prevention strategies against this emerging disease. The findings could help address the rising incidence of severe fever with thrombocytopenia syndrome (SFTS) in affected regions.

Why it matters

Potential benefit: If successful, this research could lead to the development of effective strategies to prevent the transmission of a dangerous tick-borne virus.

How similar studies have gone: Other research has shown success in understanding tick-borne diseases, but this specific investigation into SFTSV dynamics is relatively novel.

Where this research is happening

  • University of South Alabama
    Mobile, United States
    Active

Researchers

  • Principal investigator: Hermance, Meghan Elizabeth — University of South Alabama
  • Study coordinator: Hermance, Meghan Elizabeth

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.