Using mitochondrial DNA to improve early detection and predict recurrence of triple-negative breast cancer in African American women

Who could benefit from this research

What this research studies

This research investigates the role of mitochondrial DNA found in extracellular vesicles to enhance early detection and predict recurrence of triple-negative breast cancer (TNBC), particularly focusing on the disparities faced by African American women. The study aims to identify specific mitochondrial genetic alterations that may contribute to the higher rates of recurrence and metastasis in this population. By analyzing blood samples for these biomarkers, the research seeks to develop a non-invasive method for monitoring cancer progression. Patients may benefit from improved screening and personalized treatment strategies based on their mitochondrial DNA profiles.

Why it matters

Where this research is happening

• University of South Alabama
  Mobile, United States Active

Researchers

• Principal investigator: Dasgupta, Santanu — University of South Alabama
• Study coordinator: Dasgupta, Santanu

Related research

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.