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Clinical trials and research at University of Nottingham

• 39Clinical trials
• 1NIH research projects
• 1Country

Newest trials

All recruiting trials (39)

• N-WATCH: Can a simple breath device help monitor asthma in kids

  This study tests the N-Tidal C device to see if it helps monitor asthma in children aged 5 to under 16 who have wheeze or asthma and are not critically ill.

  Recruiting at 2 sites University of Nottingham · Nottingham, Nottinghamshire and 1 other locations · NCT07833826

• Lived Experience Narratives in Dementia

  This project tests a digital Online LEND Intervention that shares dementia patients’ and caregivers’ lived experiences to see if it helps wellbeing and connection.

  Recruiting at 2 sites University of Nottingham · Nottingham, England and 1 other locations · NCT07757178

• Stop PPI in active IBD: can you safely go without acid-suppressing meds?

  This study tests whether people with inflammatory bowel disease who have been on proton pump inhibitors can stop taking them and still manage their symptoms.

  Recruiting Phase 4 University of Nottingham · Nottingham · NCT07691138

• Making recruitment information clearer for people in thoracic aortic disease surveillance

  This project will test whether draft invitation letters, information sheets, and consent forms are clear and acceptable to adult staff and students at the University of Nottingham who read English, to improve recruitment for thoracic aortic disease surveillance research.

  Recruiting University of Nottingham · Nottingham · NCT07574151

• Better follow-up and testing after acute kidney injury

  This project will test different blood tests, a measured kidney clearance, body measurements, and patient interviews to see which best help adults recovering from hospitalised acute kidney injury.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT07569588

• Proof of principle for linaclotide to improve gut symptoms in cystic fibrosis

  This will test whether linaclotide can increase intestinal fluid and ease constipation and abdominal symptoms in adults with cystic fibrosis.

  Recruiting Early Phase 1 University of Nottingham · Nottingham · NCT07569419

• Action Falls for home care: improving safety and independence for older adults

  A program called Action Falls is being tested to see if it can help older people living at home who use domiciliary care avoid falls and stay independent.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire · NCT07516054

• Web-based auditory training with easy versus hard task settings to improve speech and listening

  This project will test whether easy or hard versions of a web-based auditory training program help adults with hearing loss improve speech understanding and everyday listening.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire · NCT07506408

• ReHIIT Prehabilitation in Healthy Adults

  This pilot tests a combined resistance and high‑intensity interval training program to establish baseline physiology in healthy adults before applying findings to cancer patients.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT07313332

• Ultrasonic stimulation of the ear's vagus nerve in healthy adults

  This will test whether placing a painless ultrasound device on the ear can stimulate the vagus nerve in healthy adults.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire and 1 other locations · NCT07283913

• Central pain sensitivity and its effect on nerve control of muscles in people with chronic knee pain or fibromyalgia

  This project tests whether increased central pain sensitivity is linked to changes in the nerve signals that control muscles in adults 40+ with chronic knee pain or fibromyalgia compared with pain-free volunteers.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT07281651

• Healthcare intervention experiences of ethnic minority adults in the UK

  This project will talk with ethnic minority adults and community providers in the UK to see what helps or stops people from using healthcare and falls-prevention services.

  Recruiting University of Nottingham · Nottingham · NCT07211698

• In-depth characterisation of biliary strictures and hepato‑pancreato‑biliary focal lesions to support new diagnostic technologies

  This project will collect detailed imaging and tissue data from adults with suspected bile duct, liver, pancreatic, or gallbladder lesions to help develop and test better diagnostic tools.

  Recruiting University of Nottingham · Nottingham · NCT07206355

• Thinking and brain chemistry in early psychosis

  This study will test whether a short session of gentle electrical brain stimulation changes glutamate levels and helps working memory and attention in people who recently experienced psychosis.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire · NCT07196423

• Finding the right burosumab dose for children with XLH

  This project tests whether children with X-linked hypophosphataemia can achieve good phosphate control on starting burosumab doses below 0.8 mg/kg.

  Recruiting University of Nottingham · Nottingham · NCT07183579

• Remote ischaemic conditioning to improve brain blood-flow regulation in older adults

  This project will test whether different doses of remote ischaemic conditioning (brief blood-pressure-cuff interruptions of limb blood flow) can improve dynamic cerebral autoregulation in people aged 65–85.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT07179887

• Sleep problems and recovery after a traumatic brain injury

  This project will try to see if sleep problems measured after a traumatic brain injury predict later mental health and how well adults recover their day-to-day activities.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire · NCT07120373

• Low‑methoxy pectin for inflammation, gut microbiome, and metabolic health in MASLD

  This tests whether taking daily low‑methoxy pectin for six weeks can reduce inflammation and improve gut bacteria and metabolic markers in adults with MASLD.

  Recruiting at 3 sites University of Nottingham · Nottingham, United Kingdom and 2 other locations · NCT07093346

• Characterising neuromuscular function after stroke

  This project will test how stroke affects muscle and nerve control in adults aged 40–85 who had a stroke in the last five years and still have one-sided limb weakness.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT07013188

• Detecting cancer margins during breast surgery using advanced imaging technology

  This study is testing a new imaging system that helps surgeons find cancerous tissue more accurately during breast cancer surgery to improve patient outcomes.

  Recruiting University of Nottingham · Nottingham · NCT06977698

• Impact of protein supplementation on muscle health in older men

  This study is testing whether a special protein supplement can help older men build and maintain muscle better than a regular protein supplement.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT06971822

• Postoperative NMES on both thighs with protein during abdominal cancer surgery

  This study tests whether neuromuscular electrical stimulation of both thighs after major abdominal cancer surgery helps preserve leg muscle, and whether adding protein drinks improves the effect.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT06964438

• Upper limb motor control training for cognitive function in older adults

  This study is testing if a special training program for arm movements can help healthy older adults improve their physical skills and thinking abilities.

  Recruiting University of Nottingham · Derby, Derbyshire · NCT06962722

• Observational study comparing inflammatory markers in IBD and non-IBD participants

  This study is trying to see how inflammation levels in people with Crohn's Disease and Ulcerative Colitis compare to those without these conditions when they start new treatments.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire · NCT06956703

• Effects of Pectin Supplementation on Frail Older Adults

  This study is testing if taking a daily pectin supplement can help frail older adults feel better and improve their health by looking at inflammation and gut health.

  Recruiting University of Nottingham · Nottingham, Nottingham · NCT06955975

• Combined strength, flexibility and aerobic exercise program for chronic low back pain

  This program will test whether an 8-week combined exercise plan—running or swimming/cycling plus progressive strength and flexibility work—helps adults aged 18–45 with chronic low back pain reduce pain and improve function compared with their usual exercise.

  Recruiting University of Nottingham · Nottingham, Notts · NCT06921694

• Combining high-intensity interval training with strength training for older women

  This study is testing whether a mix of high-intensity interval training and strength training can help older women stay fit and active.

  Recruiting University of Nottingham · Nottingham, Nottingham · NCT06825130

• Strategies to reduce muscle loss in aging women

  This study looks at how aging and menopause affect muscle loss in women aged 18-65 who don’t exercise regularly, to find ways to help them maintain muscle and stay healthy.

  Recruiting University of Nottingham · Nottingham · NCT06806501

• How risk influences care decisions for adults with disorders of consciousness

  This project sees how families, clinicians, and caregivers think about and manage risk when making care decisions for adults with disorders of consciousness.

  Recruiting University of Nottingham · London, London and 1 other locations · NCT06647433

• Low-dose transcranial direct current stimulation (tDCS) for tinnitus

  This study will test whether low-dose transcranial direct current stimulation (tDCS) can reduce how loud or distressing tinnitus is for adults with subjective tinnitus.

  Recruiting University of Nottingham · Nottingham · NCT06628414

• Using leucine to improve muscle growth in older adults

  This study tests if taking leucine, a type of protein, can help older adults aged 65-75 build more muscle when they exercise, by figuring out the best time to take it.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire · NCT06567665

• Effects of inulin and methylcellulose on gas production in the colon

  This study is testing whether eating meals with a mix of two types of fiber can help people with Irritable Bowel Syndrome feel less bloated and gassy.

  Recruiting at 2 sites University of Nottingham · Nottingham, Nottinghamshire and 1 other locations · NCT06551961

• Understanding itching caused by drug-induced liver injury

  This study looks at how common itching is for people with drug-induced liver injury to better understand it and help find new treatments.

  Recruiting University of Nottingham · Nottingham · NCT06446609

• Effects of changing physical activity levels on health in middle-aged adults

  This study tests how changing physical activity levels—either cutting back or increasing exercise—affects health in middle-aged adults, especially looking at issues like metabolic syndrome and cognitive decline.

  Recruiting University of Nottingham · Nottingham, Notts · NCT06377254

• Combining dietary nitrate with calorie restriction to improve cognitive and vascular function in older adults

  This study is testing if drinking beetroot juice while following a calorie-restricted diet can help improve thinking and blood flow in healthy older adults who are overweight or obese.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire · NCT06151015

• How different doses of 'Super-whey' affect muscle building in older adults

  This tests whether different doses of a leucine-rich 'Super-whey' protein help older adults increase muscle protein synthesis after resistance exercise.

  Recruiting University of Nottingham · Derby · NCT05700058

• Effects of mTOR Inhibition on Muscle Health in Older Adults

  This study is testing if a medication called Rapamune can help older adults with muscle loss get stronger when they do resistance exercises.

  Recruiting University of Nottingham · Derby · NCT05414292

• Liver injury from checkpoint inhibitors

  This project will test whether specific blood, genetic, immune, and liver tissue markers can predict who gets liver injury from checkpoint inhibitors by following people starting these drugs and those who develop liver injury.

  Recruiting University of Nottingham · Nottingham · NCT04476563

• Community-based liver health assessment using noninvasive biomarkers

  This study is trying to see how well non-invasive tests can help identify liver health issues in people at risk, like those with diabetes or obesity, by gathering information from around 2,000 participants over four years.

  Recruiting University of Nottingham · Nottingham, Notts · NCT02037867

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Investigating cancer disparities in Black patients through genetics and social factors

  This study is looking into why prostate, breast, and pancreatic cancers tend to be more aggressive and happen earlier in Black patients, especially in West Africa, by exploring different factors like genetics and environment, and it aims to gather important information to help understand these differences better.

  NIH research University of Nottingham · Nottingham, United Kingdom · NIH-11045974

Quick answers

How many clinical trials run by University of Nottingham are recruiting right now?

39, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United Kingdom. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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