Low-dose transcranial direct current stimulation (tDCS) for tinnitus
Official title: Transcranial Direct Current Stimulation (tDCS) for Tinnitus - Effects of Multiple Treatment Sessions: a Randomised-controlled Pilot Study
Run by University of Nottingham · NCT06628414 · Data updated 2026-11-12
This study will test whether low-dose transcranial direct current stimulation (tDCS) can reduce how loud or distressing tinnitus is for adults with subjective tinnitus.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University of Nottingham Academic / other |
| Locations | 1 site (Nottingham) |
| Status | Recruiting |
| Started | December 1, 2024 |
| Main results expected | September 2026 |
| Study ends | September 2026 |
| Registry record updated | February 12, 2026 |
| Trial ID | NCT06628414 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or over with subjective idiopathic tinnitus who can consent in English and are medically eligible for tDCS are the ideal candidates.
✕Probably not a fit
People with objective tinnitus, those under 18, individuals unable to safely undergo tDCS, or those who cannot provide informed consent in English are unlikely to benefit or be eligible for this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study will apply low-dose tDCS to adults with subjective idiopathic tinnitus to identify the most effective stimulation regimens and the most sensitive outcome measures for future trials. Eligible participants who can safely undergo tDCS and provide informed consent in English will receive controlled stimulation sessions following predefined procedures, with randomisation and blinding used where feasible. The primary focus is on safety, tolerability, and detecting a signal of clinical benefit rather than providing definitive proof of efficacy. The work is conducted at the University of Nottingham and is intended to guide a larger, definitive randomised trial.
Why it matters
Potential benefit: If successful, this approach could reduce tinnitus loudness or distress and improve daily functioning for some patients.
How similar studies have gone: Several small previous studies of tDCS for tinnitus have reported some benefit, but the evidence is limited and inconsistent, so larger pilot work is needed.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18 or over * Suffering from subjective idiopathic tinnitus * Sufficient understanding of English to be able to provide informed consent * Able to safely undergo tDCS Exclusion Criteria: * Aged under 18 * Not suffering from tinnitus or suffering from objective tinnitus * Insufficient understanding of English to be able to provide informed consent * Unable to safely undergo tDCS as assessed by tDCS Safety Questionnaire * Having taken part in a research study in the last 3 months involving invasive procedures or an inconvenience allowance
Where it's running
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University of Nottingham
Nottingham, United Kingdom Recruiting
Study contacts
- Principal investigator: Magdalena Sereda, PhD — University of Nottingham
- Study coordinator: Magdalena Sereda, PhD
- Email: magdalena.sereda@nottingham.ac.uk
- Phone: 00441158232625
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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DeepTMS for chronic tinnitus using different H-coils
This study tests whether deep repetitive transcranial magnetic stimulation with different H-coils can reduce tinnitus distress in adults with chronic tinnitus, compared to placebo.
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Non-Invasive Neurofeedback for Tinnitus Distress
This trial tests whether real-time neurofeedback training can reduce distress from tinnitus in adults with bothersome symptoms.
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TRTL-913 in adults with tinnitus: safety and signals of benefit
This trial tests TRTL-913 versus placebo in healthy adults and in adults with tinnitus to see if it is safe, tolerable, and potentially helpful for tinnitus patients.
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Foot reflexology or ta-VNS for tinnitus in adults
This trial tests whether foot reflexology, left-ear vagus nerve stimulation, or auricular acupressure can help reduce tinnitus symptoms in adults with tinnitus.
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Mild 8 dB hearing amplification for tinnitus in adults with normal hearing
This test tries wearing hearing aids that add a small (8 dB) boost to see if they reduce tinnitus symptoms in adults with normal hearing.
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Neck nerve electrical stimulation combined with sound-frequency training for chronic tonal tinnitus
This trial tests whether pairing a safe electrical stimulation of the greater occipital nerve with an active sound-frequency training task can reduce tinnitus loudness and distress in adults with chronic tonal tinnitus.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.