Investigating cancer disparities in Black patients through genetics and social factors
Official title: Societal, Ancestry, Molecular and Biological Analyses of Inequalities: SAMBAI
Funded at University of Nottingham · NIH-11045974 · Data updated 2026-11-12
This study is looking into why prostate, breast, and pancreatic cancers tend to be more aggressive and happen earlier in Black patients, especially in West Africa, by exploring different factors like genetics and environment, and it aims to gather important information to help understand these differences better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nottingham NIH-funded |
| Lab location | 1 site (Nottingham, United Kingdom) |
| Project start | May 1, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $69,931 |
| NIH project number | 1OT2CA297505-01 |
| Project ID | NIH-11045974 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Black individuals, particularly those with a family history of prostate, breast, or pancreatic cancers.
✕Less likely to help
Patients who do not identify as Black or do not have a family history of the targeted cancers may not benefit from this research.
What this research studies
This research focuses on understanding why prostate, breast, and pancreatic cancers are more aggressive and occur earlier in Black patients, particularly in West Africa. The team will analyze genetic, environmental, and social factors that contribute to these disparities. By creating a biobank and data repository, they aim to gather comprehensive information that can help identify the causes of these inequalities. The research will involve collaboration with scientists from the US, Africa, and the UK to ensure a diverse and inclusive approach.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer prevention and treatment strategies tailored for Black patients.
How similar studies have gone: Previous research has shown success in understanding cancer disparities through genetic and social analyses, making this approach promising.
Where this research is happening
-
University of Nottingham
Nottingham, United Kingdom Active
Researchers
- Principal investigator: Mongan, Nigel — University of Nottingham
- Study coordinator: Mongan, Nigel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.