N-WATCH: Can a simple breath device help monitor asthma in kids
Official title: N-WATCH: Nottingham Wheeze Assessment in Tidal Children
Run by University of Nottingham · NCT07833826 · Data updated 2026-11-12
This study tests the N-Tidal C device to see if it helps monitor asthma in children aged 5 to under 16 who have wheeze or asthma and are not critically ill.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 5 Years to 15 Years |
| Sex | All |
| Enrollment | 340 (estimated) |
| Sponsor | University of Nottingham Academic / other |
| Locations | 2 sites (Nottingham, Nottinghamshire and 1 other locations) |
| Status | Recruiting |
| Started | July 15, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | September 22, 2026 |
| Trial ID | NCT07833826 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 5 to under 16 years who have wheeze, bronchospasm, or asthma and are able to use a mouthpiece for 90 seconds, not in life-threatening distress.
✕Probably not a fit
Children who are in life-threatening respiratory distress or unable to use the device as required may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational program evaluates whether the N-Tidal C device can aid home and clinical monitoring of pediatric asthma and wheeze. It includes two workstreams: one for children presenting with acute wheeze or bronchospasm, and another for routine lung function testing in similar age groups. The aim is to determine if the device’s CO2 measurements reflect lung status and could support earlier intervention. Participants must meet age criteria, have a non-critical respiratory condition, and be able to use a mouthpiece for 90 seconds. The study is led by the University of Nottingham with Nottingham University Hospitals NHS Trust as collaborators and sites in Nottingham.
Why it matters
Potential benefit: If successful, the device could enable easier, at-home monitoring and earlier detection of deterioration in pediatric asthma.
How similar studies have gone: Preliminary adult data and related respiratory devices suggest potential utility, but pediatric validation remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Workstream 1 inclusion criteria i) Aged 5 years or older, and less than 15 years plus 32 weeks of age ii) Participant has presented to hospital with acute wheeze, bronchospasm or asthma iii) Participant is not critically ill and is able to breathe into a mouthpiece for 90seconds. Workstream 2 inclusion criteria i) Participant 5 years or older, and less than 16 years of age. ii) Participant is due to have routine lung function testing. Exclusion criteria i) Life threatening respiratory difficulties (defined as cyanosis, oxygen saturations less than 92% despite oxygen supplementation, silent chest on auscultation, poor respiratory effort, fatigue or exhaustion, agitation or reduced level of consciousness) ii) Participation in another research project whose protocol prevents participation in this project.
Where it's running
-
Nottingham University Hospitals NHS Trust
Nottingham, Nottinghamshire, United Kingdom Recruiting -
Nottingham University Hospitals NHS Trust
Nottingham, Nottinghamshire, United Kingdom Recruiting
Study contacts
- Study coordinator: Andrew P Prayle, BMBS
- Email: andrew.prayle@nottingham.ac.uk
- Phone: +44 (0) 115 9249924
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.