Clinical trial Recruiting at 1 site Interventional Ages 60 and up Women only

Combining high-intensity interval training with strength training for older women

Official title: Feasibility and Preliminary Efficacy of High-intensity Interval Training Combined with Muscle-strength Training in Older Women: Pilot Randomized Controlled Trial

Run by University of Nottingham · NCT06825130 · Data updated 2026-11-12

This study is testing whether a mix of high-intensity interval training and strength training can help older women stay fit and active.

Quick facts

Study typeInterventional
Ages60 Years and up
SexWomen only
Enrollment20 (estimated)
SponsorUniversity of Nottingham
Academic / other
Locations1 site (Nottingham, Nottingham)
StatusRecruiting
StartedFebruary 1, 2025
Main results expectedAugust 31, 2026
Study endsDecember 31, 2026
Registry record updatedFebruary 13, 2025
Trial IDNCT06825130 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women aged 60 and older who are not currently engaged in regular high-intensity aerobic or muscle strength training.

Probably not a fit

Patients with diagnosed cardiovascular disease, kidney disease, diabetes, or other significant health issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the practicality and effectiveness of combining high-intensity interval training (HIIT) with muscle-strength training specifically for older women. It aims to address the issue of muscle mass loss and inactivity among this demographic by providing a time-efficient exercise regimen that is both enjoyable and beneficial. Participants will engage in structured exercise sessions at the University of Nottingham, and their fitness levels will be assessed through cardiopulmonary exercise testing. The study seeks to determine if this combined approach can improve overall fitness in older women.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the physical fitness and quality of life for older women by promoting more effective and enjoyable exercise routines.

How similar studies have gone: Previous studies have shown positive outcomes with HIIT in older populations, suggesting that this combined approach may also be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Females (biologically at birth)
* At least 60 years of age at the time of signing the informed consent
* Non-smoker, including electronic cigarettes
* Not participating in routine high-intensity aerobic or muscle strength exercise training (≥ 75 min/week of structured vigorous aerobic exercise, or 2 times /week of structured muscle strength training)
* Able to perform a cardiopulmonary exercise testing (CPET) to exhaustion
* willing to complete baseline and follow-up measures, and attend prescribed exercise sessions at the University of Nottingham
* willing and able to give informed consent for participation in the study

Exclusion Criteria:

* Diagnosed with cardiovascular disease, kidney disease, diabetes, obstructive pulmonary disease, or uncontrolled hypertension
* History or current neurological or psychiatric illness, or motor or cognitive restrictions
* Contraindications to symptom-limited cardiopulmonary exercise testing (CPET), including resting hypertension with systolic blood pressure \>200 mmHg or diastolic blood pressure \> 110 mmHg, uncorrected medical conditions, such as significant anemia, important electrolyte imbalance, and hyperthyroidism, mental impairment with limited ability to cooperate, physical disability that precludes safe and adequate testing.
* Having taken part in a research study in the last 3 months involving invasive procedures or an inconvenience allowance.

Where it's running

  • David Greenfield Humnn Physiology Unit (DGHPU), University of Nottingham
    Nottingham, Nottingham, United Kingdom
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.