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Clinical trials and research at National University Hospital, Singapore

• 49Clinical trials
• 1New in 30 days
• 3Countries

Newest trials

All recruiting trials (49)

• Precision brain mapping to guide neuromodulation after spontaneous intracerebral hemorrhage

  This trial tests whether personalized transcranial magnetic stimulation targets, identified with individual brain maps, help improve motor and cognitive functions after spontaneous ICH.

  Recruiting at 2 sites National University Hospital, Singapore · Singapore and 1 other locations · NCT07908264

• Multimodal Prehabilitation for Gastric Cancer Patients

  This program tests whether a combined pre- and post-operative wellness plan can reduce inflammation after gastric cancer surgery in adults.

  Recruiting National University Hospital, Singapore · Singapore · NCT07839702

• Different ways to use non-invasive brain stimulation to help stroke recovery

  This study tests if different non-invasive brain stimulation methods can improve motor and language recovery for stroke patients, depending on their goals and medical history.

  Recruiting at 2 sites National University Hospital, Singapore · Singapore and 1 other locations · NCT07786649

• Mepitel Film for Preventing Radiation Dermatitis in Breast Cancer Patients in Singapore

  This observational study tests whether Mepitel Film can help prevent radiation dermatitis in breast cancer patients getting whole breast or chest wall radiotherapy in Singapore.

  Recruiting National University Hospital, Singapore · Singapore · NCT07729423

• Comparing Acute Medical Unit care versus usual ward care for adults with sudden medical illnesses

  This research will see if care in an Acute Medical Unit (AMU) leads to better outcomes than usual general-ward care for adults admitted from the emergency department with infections, falls, or COPD flare-ups.

  Recruiting National University Hospital, Singapore · Singapore · NCT07536035

• SPICE: Community-based pathway to screen and prevent declines in older adults' physical and mental abilities in Singapore

  This program tries a digital, community screening and targeted support pathway to prevent declines in physical and mental abilities for adults aged 60 and older in Singapore.

  Recruiting National University Hospital, Singapore · Singapore · NCT07525583

• Transcutaneous spinal stimulation plus robotic arm training for people with cervical spinal cord injury

  This project will try adding transcutaneous spinal cord stimulation (tSCS) to robotic arm therapy to see if it improves arm and hand function in adults with chronic incomplete cervical spinal cord injuries.

  Recruiting National University Hospital, Singapore · Singapore, Singapore · NCT07432321

• Liquid biopsy pre-screen to reduce unnecessary low-dose CT for high-risk lung cancer

  This will test a blood-based liquid biopsy to see if it can identify high-risk people who can safely skip or delay a low-dose CT scan for lung cancer.

  Recruiting National University Hospital, Singapore · Singapore · NCT07358715

• Antigen-targeted CAR T therapy for relapsed or high-risk B-cell lymphoma

  This research will test a personalized CAR T-cell treatment that targets CD19, and sometimes CD22, in people with relapsed or high‑risk B‑cell lymphoma.

  Recruiting Phase 1/2 National University Hospital, Singapore · Singapore, Singapore · NCT07319676

• Skin cancer self-detection education: does framing affect outcomes?

  This trial tests a skin cancer education program to see if gain- or loss-framed messages help people with skin of color detect skin changes and adopt sun-protective behaviors.

  Recruiting National University Hospital, Singapore · Singapore · NCT07247123

• Pulpotomy versus root canal treatment for extremely deep caries

  This study tests whether full pulpotomy works as well as root canal treatment for people aged 12 and older with extremely deep caries treated in a university dental clinic.

  Recruiting National University Hospital, Singapore · Singapore · NCT07242742

• Myo-inositol supplementation during pregnancy for women with Type 2 diabetes

  This pilot will test whether taking myo-inositol supplements during pregnancy helps women with Type 2 diabetes support fetal growth and newborn wellbeing.

  Recruiting National University Hospital, Singapore · Singapore, Singapore · NCT07241221

• Dupilumab for nephrotic syndrome in children

  This study will try dupilumab to help children with steroid‑dependent or frequently relapsing nephrotic syndrome stay in remission and relapse less often.

  Recruiting at 2 sites Phase 2 National University Hospital, Singapore · Singapore, Singapore and 1 other locations · NCT07091175

• Alpha-ketoglutarate to improve recovery after coronary artery bypass

  This trial will try giving alpha-ketoglutarate around the time of elective CABG to see if it reduces an exaggerated immune response and helps people aged 50 and older recover faster.

  Recruiting at 2 sites Phase 4 National University Hospital, Singapore · Singapore, Singapore and 1 other locations · NCT07031128

• Screening for early nasopharyngeal (nose) cancer

  This project tests whether blood and saliva markers can find nasopharyngeal cancer early in adults aged 35 to 60 who are at higher risk because of ethnicity or family history.

  Recruiting at 2 sites National University Hospital, Singapore · Singapore and 1 other locations · NCT07019870

• CPAP versus mandibular advancement mouthpiece for sleep apnea in people with mild cognitive impairment

  This project will try to see if a mandibular advancement device (a dental mouthpiece) works as well as nightly CPAP to improve thinking and memory in people over 45 with moderate-to-severe obstructive sleep apnea and mild cognitive impairment.

  Recruiting National University Hospital, Singapore · Kent Ridge, Please Select · NCT06983769

• Sacituzumab govitecan for advanced salivary gland and differentiated thyroid cancers

  This study will try sacituzumab govitecan in adults whose salivary gland cancer or radioactive-iodine–refractory differentiated thyroid cancer has spread or come back and cannot be removed by surgery.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore · NCT06923826

• Using physical tests to improve discharge planning for older adults

  This study tests if simple physical tests can help doctors and therapists make better plans for older adults leaving the hospital.

  Recruiting National University Hospital, Singapore · Singapore · NCT06903832

• Neoadjuvant ADG126 plus pembrolizumab for stage II–III colorectal cancer

  This study will try two pre-surgery doses of ADG126 together with pembrolizumab for people with stage II or III colorectal cancer to see if the combination is safe and can shrink tumors before surgery.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore · NCT06846268

• Using pulsed electromagnetic fields to prevent physical decline in hospitalized cancer patients

  This study is testing if pulsed electromagnetic fields can help hospitalized cancer patients maintain their physical strength and function while they are being treated.

  Recruiting National University Hospital, Singapore · Kent Ridge and 1 other locations · NCT06744764

• Using a dental stent to protect taste in nasopharyngeal cancer patients during treatment

  This study is testing if a special dental stent can help people with nasopharyngeal cancer keep their sense of taste while they undergo chemotherapy and radiation treatment.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore and 1 other locations · NCT06733948

• Digital psychotherapeutic app to help people with eczema, psoriasis, or urticaria feel better

  A mobile app delivering psychotherapeutic techniques is tested to see if it improves quality of life for people with inflammatory skin conditions.

  Recruiting National University Hospital, Singapore · Singapore · NCT06702293

• Effect of taking omeprazole with atorvastatin on atorvastatin lactone levels

  For adults on atorvastatin, this 30-day randomized test will see if adding omeprazole raises levels of atorvastatin lactone.

  Recruiting Phase 4 National University Hospital, Singapore · Singapore · NCT06690164

• Evaluating treatments for joint pain in menopausal women

  This study is testing whether muscle strengthening exercises, estrogen therapy, or a combination of both can help relieve joint pain in women going through menopause.

  Recruiting Phase 2/3 National University Hospital, Singapore · Singapore · NCT06530459

• ETC-159 plus pembrolizumab for advanced, platinum‑resistant MSS/pMMR ovarian cancer

  This trial will test whether the oral Wnt inhibitor ETC-159 given with pembrolizumab can help women with advanced, platinum‑resistant MSS/pMMR ovarian cancer.

  Recruiting Phase 1 National University Hospital, Singapore · Singapore, Singapore and 1 other locations · NCT06513624

• Comparing Ready-to-Eat Meals with Standard Care for Bariatric Surgery Preparation

  This study is testing if ready-to-eat low-calorie meals can help people preparing for bariatric surgery stick to their diet better and feel more satisfied compared to regular liquid meal replacements.

  Recruiting at 2 sites National University Hospital, Singapore · Singapore and 1 other locations · NCT06461247

• Doxycycline added to standard treatment for central nervous system tuberculosis

  This trial tests whether adding doxycycline to standard anti‑TB therapy and corticosteroids helps adults with central nervous system tuberculosis live longer or have less severe neurological disability.

  Recruiting at 5 sites Phase 2 National University Hospital, Singapore · Medan, Medan and 5 other locations · NCT06446245

• Reducing dosing frequency of immune checkpoint inhibitors in advanced cancers

  This study is testing if giving immune checkpoint inhibitors less often can still help people with advanced cancers feel better while making treatment easier and cheaper.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore · NCT06422403

• Improving survival in young patients with B-ALL using risk-based therapy

  This study is testing whether a tailored chemotherapy approach based on genetic risk can improve survival for children and young adults with B-ALL in Singapore and Malaysia.

  Recruiting at 3 sites Phase 2 National University Hospital, Singapore · Kuala Lumpur and 2 other locations · NCT06336395

• Brachytherapy treatment for cervical cancer using interstitial needles

  This study is testing a new way to deliver high dose radiation treatment for cervical cancer using special needles to see if it is safe and effective for patients in an outpatient setting.

  Recruiting National University Hospital, Singapore · Singapore · NCT06284031

• Investigating immune and metabolic factors in early cardiovascular disease

  This study is testing if using digital wearables and AI-driven lifestyle changes can help people with early cardiovascular disease improve their heart health.

  Recruiting National University Hospital, Singapore · Singapore · NCT06211868

• Early activation and sleep-promoting routines to reduce delirium after CABG

  We will test whether early occupational therapy combined with sleep-promoting routines (DREAMS-OT) can reduce delirium in adults undergoing elective CABG surgery.

  Recruiting National University Hospital, Singapore · Singapore · NCT06107517

• Exploring afatinib for advanced lung cancer with specific mutations

  This study is testing if the drug afatinib can help people with advanced lung cancer that has a specific mutation feel better and manage their disease.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore · NCT06062823

• Spinal cord stimulation plus robotic walking training for chronic spinal cord injury

  This project will test whether adding non-invasive spinal cord stimulation to robotic gait training helps people with chronic incomplete spinal cord injury walk and move better and improve quality of life.

  Recruiting National University Hospital, Singapore · Singapore, Singapore · NCT05921175

• AI tool for personalized treatment in patients with advanced solid tumors

  This study is testing a new tool that uses genetic information to suggest personalized treatments for patients with advanced solid tumors who have already tried several therapies.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore · NCT05719428

• Evaluating a new imaging technique for liver cancer

  This study is testing a new type of scan to see if it can better detect and understand liver cancer in patients compared to standard imaging methods.

  Recruiting Phase 1 National University Hospital, Singapore · Singapore · NCT05687747

• Optimizing blood flow to protect the brain after cardiac arrest

  This study is testing a personalized blood pressure management plan to see if it can help protect the brains of people who have had a cardiac arrest.

  Recruiting National University Hospital, Singapore · Singapore · NCT05679739

• Limb cryocompression to prevent chemotherapy-related nerve damage

  We will test whether cooling your arms and legs with the Paxman Limb Cryocompression System can prevent nerve damage in people with cancer receiving weekly paclitaxel chemotherapy.

  Recruiting National University Hospital, Singapore · Singapore and 1 other locations · NCT05606068

• Optimizing drug combinations for recurrent high grade astrocytic glioma using patient-derived organoids

  This study is testing a new way to find the best drug combinations for treating recurrent high-grade brain tumors using samples from patients' tumors grown in the lab.

  Recruiting National University Hospital, Singapore · Singapore and 1 other locations · NCT05532397

• Combining ADG106 and pembrolizumab for advanced solid tumors and triple negative breast cancer

  This study is testing if combining two treatments, ADG106 and pembrolizumab, can help people with advanced solid tumors, especially those with triple negative breast cancer, feel better and respond to treatment.

  Recruiting Phase 1/2 National University Hospital, Singapore · Singapore · NCT05491083

• Using doxycycline to improve lung function in tuberculosis patients

  This study is testing if adding doxycycline to the standard treatment for tuberculosis can help improve lung function and reduce damage in patients with lung infections.

  Recruiting at 3 sites Phase 3 National University Hospital, Singapore · Kota Kinabalu, Sabah and 5 other locations · NCT05473520

• Personalised azacitidine combination therapy using AI-guided drug selection and dosing

  This study tests whether AI tools can pick the best azacitidine drug combination and personalise dosing for adults with certain solid tumours using each person's biopsy sample.

  Recruiting Phase 1/2 National University Hospital, Singapore · Singapore · NCT05381038

• Induction gemcitabine and cisplatin with or without pembrolizumab and bevacizumab for locally advanced nasopharyngeal cancer

  This trial tests whether adding pembrolizumab and bevacizumab to induction gemcitabine and cisplatin improves metabolic complete response and survival in adults with locally advanced, EBV-positive nasopharyngeal cancer.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore · NCT05305131

• Combining Lenvatinib and Letrozole for Advanced Breast Cancer

  This study is testing if combining two drugs, lenvatinib and letrozole, can help women with advanced breast cancer that hasn't improved with previous treatments.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore · NCT05181033

• Using Osimertinib for treating advanced EGFR-positive lung cancer

  This study is testing if the oral medication Osimertinib can help people with advanced EGFR-positive lung cancer who haven't had treatment before feel better and live longer.

  Recruiting National University Hospital, Singapore · Singapore · NCT05037331

• Combining Selinexor and Talazoparib for Advanced Triple Negative Breast Cancer

  This study is testing a combination of two drugs, Selinexor and Talazoparib, to see if they can help people with advanced triple negative breast cancer.

  Recruiting Phase 1/2 National University Hospital, Singapore · Singapore · NCT05035745

• Tracking the health of elderly patients undergoing major surgery in Singapore

  This study is tracking the health of older patients aged 65 and up who are having major surgeries to see how they recover and improve their care in the future.

  Recruiting National University Hospital, Singapore · Singapore and 1 other locations · NCT04792554

• AZD5363 with olaparib and durvalumab for advanced or metastatic solid tumors

  This trial tries giving AZD5363 together with olaparib and durvalumab to adults with advanced or metastatic solid tumors to see if the combination is safe and to find a tolerable dose.

  Recruiting Phase 1 National University Hospital, Singapore · Singapore, Singapore · NCT03772561

• Comparing StrataXRT to standard care for preventing skin issues in head and neck cancer patients

  This study is testing if a new silicone gel called StrataXRT can help prevent skin problems in patients with head and neck cancer who are getting radiation treatment, compared to the usual cream they receive.

  Recruiting National University Hospital, Singapore · Singapore · NCT03394417

Quick answers

How many clinical trials run by National University Hospital, Singapore are recruiting right now?

49, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in Singapore (49 trials), Malaysia (3 trials), Indonesia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 11, Phase 1/2: 4, Phase 1: 3, Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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