Digital psychotherapeutic app to help people with eczema, psoriasis, or urticaria feel better

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial tests a mobile digital toolkit offering psychotherapeutic strategies such as mindfulness, CBT, and ACT for patients with eczema, psoriasis, or chronic urticaria. Participants are assigned to use the app over a 32-week period to see if it reduces QoL burden compared with standard care. The study focuses on whether integrating mental health approaches within dermatology care can improve patient-reported outcomes and daily functioning. The app targets skin-related itch, sleep disturbance, anxiety, and depression associated with chronic inflammatory skin diseases. The trial also evaluates how the intervention can be implemented within real-world dermatology settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with psoriasis, eczema or chronic urticaria diagnosed by a dermatologist
* Aged 16 or older
* Peak pruritus intensity of 4 or more on a 11-point numerical rating scale (0-10, with 10 representing worst itch)
* Able to engage with a mobile application in the English language

Exclusion Criteria:

* Patients with active psychiatric symptoms (e.g. active suicidal ideation, psychosis, delusions)
* Patients with unstable psychiatric condition, characterized by

  o Hospital inpatient admission for a psychiatric condition or initiation of a psychotropic medication in the prior 3 months
* Patients with unstable dermatological condition, characterized by

  * Recent flare of the skin condition within the last 2 weeks, including diagnosis of a flare by a doctor, use of systemic steroids, oral antibiotics, wet wrap rescue therapy, oral antivirals, or increase in frequency of phototherapy or dose of systemic medications for the dermatological condition within the last 2 weeks OR
  * Any of the following within 3 months

    * inpatient admission for a dermatological condition
    * Initiation of phototherapy
    * Initiation of systemic therapy (conventional immunosuppressive agent, biologics, JAK inhibitors) within the last 3 months.

Where it's running

• National University Hospital
  Singapore, Singapore Recruiting

Study contacts

• Principal investigator: Ellie Choi, MBBS — National University Hospital, Singapore
• Study coordinator: Ellie Choi, MBBS
• Email: dermresearchec@nuhs.edu.sg
• Phone: 65 6908 2222

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.