Clinical trial Recruiting at 1 site Observational Ages 21 and up

Comparing Acute Medical Unit care versus usual ward care for adults with sudden medical illnesses

Official title: Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness in Singapore and Decrease Utilisation of Acute Care Bed-days

Run by National University Hospital, Singapore · NCT07536035 · Data updated 2026-11-12

This research will see if care in an Acute Medical Unit (AMU) leads to better outcomes than usual general-ward care for adults admitted from the emergency department with infections, falls, or COPD flare-ups.

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Quick facts

Study typeObservational
Ages21 Years and up
SexAll
Enrollment220 (estimated)
SponsorNational University Hospital, Singapore
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Singapore)
StatusRecruiting
StartedSeptember 30, 2024
Main results expectedMay 31, 2026
Study endsMay 31, 2026
Registry record updatedApril 17, 2026
Trial IDNCT07536035 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 21 or older admitted from the emergency department with acute medical illnesses such as infection, falls-related problems, or COPD exacerbation who are not pregnant and not receiving active chemotherapy.

Probably not a fit

People younger than 21, pregnant patients, patients on active chemotherapy, those admitted for less than 24 hours, or patients requiring acute thrombolysis or intravascular intervention for stroke are excluded and unlikely to benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Investigators will compare patients admitted from the emergency department to an Acute Medical Unit (AMU) with similar patients admitted directly to general wards at a major Singapore hospital, using observational methods to match similar clinical profiles. The team will examine clinical effectiveness and cost-effectiveness outcomes such as length of stay, complications, readmissions, and resource use. Key inclusion criteria are adults 21 and older with acute medical illnesses including infection-related conditions, falls/disequilibrium, or COPD exacerbations, while people who are pregnant, on active chemotherapy, admitted under 24 hours, or requiring acute stroke interventions are excluded. The study leverages Singapore’s national healthcare setting and academic partnerships to compare how different interface care models perform in real-world practice.

Why it matters

Potential benefit: If successful, this could help hospitals deliver more timely, appropriate, and cost-effective care for adults with acute medical problems, potentially reducing complications, length of stay, and readmissions.

How similar studies have gone: Other implementations of Acute Medical Units and interface care models have shown generally favorable but variable results—often reducing length of stay and improving throughput—so effectiveness appears to depend on local implementation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* AMU inclusion criteria - admission from ED to AMU directly
* Control group inclusion criteria - admission from ED to GW directly
* Acute medical illnesses that includes infection-related conditions, falls-disequilibrium, and acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD).

Exclusion Criteria:

* Below 21 years old
* Patients undergoing active chemotherapy
* Patients with active pregnancy
* Patients admitted less than 24 hours
* Cerebrovascular disease requiring thrombolysis or intravascular intervention

Where it's running

  • National University Hospital
    Singapore, Singapore
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.