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Clinical trial Recruiting at 1 site Observational Ages 65 to 100

Tracking the health of elderly patients undergoing major surgery in Singapore

Official title: Singapore Perioperative Ageing Study (Sing-PAS)

Run by National University Hospital, Singapore · NCT04792554 · Data updated 2026-11-12

This study is tracking the health of older patients aged 65 and up who are having major surgeries to see how they recover and improve their care in the future.

More Aging trials

Quick facts

Study typeObservational
Ages65 Years to 100 Years
SexAll
Enrollment600 (estimated)
SponsorNational University Hospital, Singapore
Academic / other
Locations2 sites (Singapore and 1 other locations)
StatusRecruiting
StartedApril 7, 2021
Main results expectedDecember 2025
Study endsDecember 2026
Registry record updatedOctober 6, 2022
Trial IDNCT04792554 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are elderly patients aged 65 and older who are scheduled for major non-cardiac surgery.

Probably not a fit

Patients with a history of psychiatric disease, those undergoing emergency surgeries, or non-residents of Singapore may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Singapore Perioperative Ageing Study aims to create a comprehensive database to monitor elderly patients aged 65 and above who are undergoing major non-cardiac surgeries. This observational study will follow patients from the preoperative phase through to five years post-surgery, focusing on outcomes such as postoperative delirium and myocardial injury. By understanding the challenges faced by this demographic, the study seeks to develop sustainable clinical strategies to improve their surgical outcomes and quality of life. The research will involve neurocognitive assessments and blood tests to gather relevant health data.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and quality of life for elderly patients.

How similar studies have gone: Other studies focusing on elderly surgical patients have shown the importance of tailored perioperative care, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Elderly patients aged 65 years and above
* Undergoing major non-cardiac surgery, defined as surgery that is predicted to be at least 2 hours and requiring at least 1 day postoperative stay in the hospital
* English, Chinese or Malay speaking
* Ability to provide informed consent

Exclusion Criteria:

* History of psychiatric disease
* Illiterate
* An active history of substance abuse.
* Undergoing neurological procedures
* Undergoing emergency surgeries
* Has a second surgery planned within 5 days of index surgery
* Non-resident of Singapore
* Severe hearing and/or speech impairment

Where it's running

  • National University Hospital
    Singapore, Singapore     Recruiting
  • Alexandra Hospital
    Singapore, Singapore     Active not recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Postoperative Delirium 64Aging 2413Myocardial Injury 29National University Hospital, Singapore 49
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.