Tracking the health of elderly patients undergoing major surgery in Singapore
Singapore Perioperative Ageing Study (Sing-PAS)
National University Hospital, Singapore · NCT04792554
This study is tracking the health of older patients aged 65 and up who are having major surgeries to see how they recover and improve their care in the future.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 65 Years to 100 Years |
| Sex | All |
| Sponsor | National University Hospital, Singapore (other) |
| Locations | 2 sites (Singapore and 1 other locations) |
| Trial ID | NCT04792554 on ClinicalTrials.gov |
What this trial studies
The Singapore Perioperative Ageing Study aims to create a comprehensive database to monitor elderly patients aged 65 and above who are undergoing major non-cardiac surgeries. This observational study will follow patients from the preoperative phase through to five years post-surgery, focusing on outcomes such as postoperative delirium and myocardial injury. By understanding the challenges faced by this demographic, the study seeks to develop sustainable clinical strategies to improve their surgical outcomes and quality of life. The research will involve neurocognitive assessments and blood tests to gather relevant health data.
Who should consider this trial
Good fit: Ideal candidates for this study are elderly patients aged 65 and older who are scheduled for major non-cardiac surgery.
Not a fit: Patients with a history of psychiatric disease, those undergoing emergency surgeries, or non-residents of Singapore may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and quality of life for elderly patients.
How similar studies have performed: Other studies focusing on elderly surgical patients have shown the importance of tailored perioperative care, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Elderly patients aged 65 years and above * Undergoing major non-cardiac surgery, defined as surgery that is predicted to be at least 2 hours and requiring at least 1 day postoperative stay in the hospital * English, Chinese or Malay speaking * Ability to provide informed consent Exclusion Criteria: * History of psychiatric disease * Illiterate * An active history of substance abuse. * Undergoing neurological procedures * Undergoing emergency surgeries * Has a second surgery planned within 5 days of index surgery * Non-resident of Singapore * Severe hearing and/or speech impairment
Where this trial is running
Singapore and 1 other locations
- National University Hospital — Singapore, Singapore (RECRUITING)
- Alexandra Hospital — Singapore, Singapore (ACTIVE_NOT_RECRUITING)
Study contacts
- Principal investigator: Lian Kah Ti — National University Health System
- Study coordinator: Lian Kah Ti
- Email: lian_kah_ti@nuhs.edu.sg
- Phone: 67724200
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Postoperative Delirium, Aging, Myocardial Injury, Geriatrics