Sponsor or institution
Clinical trials and research at Nathan S. Kline Institute for Psych Res
As of November 12, 2026, Find a Trial lists 43 NIH-funded research projects at this institution, with $31.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 43NIH research projects
NIH-funded research (newest 40 of 43)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Understanding how brain activity changes may drive Alzheimer’s disease progression in a mouse model
Researchers are testing how changes in brain signals and protein cleanup processes affect the development of Alzheimer’s disease in mice.
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Addressing racial disparities in opioid overdose deaths using open source peer recovery coaching and AI-powered mobile health
A small, open-source program uses AI-powered texting and peer recovery coaching to help Black and Latinx people who use opioids access support and stay in treatment, aiming to reduce overdose deaths and close gaps in care.
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Hyperexcitability in Alzheimer's Disease and how it affects brain signals
Aimed at people with Alzheimer’s disease or related dementia, this grant studies abnormal brain activity that happens early in the disease and tests whether stopping it can help cognition and amyloid buildup.
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Understanding how a brain visual pathway linked to social cues goes wrong in schizophrenia
Aiming to map and understand how a special brain visual pathway that helps read social cues may be disrupted in people with schizophrenia, to identify potential targets for future treatments.
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Circuits for detecting surprising events in V1 (visual cortex)
This grant studies how the brain automatically notices unexpected visual events, focusing on autism-related brain processing, to understand how people with autism may experience and react to their surroundings.
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CB1 signaling and alcohol effects in development
This project studies how alcohol exposure before birth changes brain signaling and behavior later in life, with a focus on CB1 receptors in the hippocampus and prefrontal cortex.
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Dynamic brain circuits in primates: how hearing, multisensory cues, and memory work together
Researchers are studying how the primate brain processes sounds alongside sights, eye movements, and memory to understand natural, real-world listening and behavior.
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Virtual reality mindfulness to reduce aggression in schizophrenia
A VR mindfulness program is being tested to help reduce aggressive outbursts in people with schizophrenia.
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Organizing and sharing brain imaging and behavior data
This project will collect, clean, and share brain imaging and behavioral data from people and primates so researchers can study brain activity and disorders more easily.
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Combining different brain recordings to map slow brain activity
This project brings together EEG, fMRI, and other brain recordings from people and primates to map slow brain activity that influences thinking and behavior.
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Linking slow brain rhythms to tiny brain circuits that shape attention and arousal
This project builds computer models to connect slow brain activity seen on EEG and fMRI with the activity of brain cells and circuits that influence attention and arousal.
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Slow brain activity across levels and how it affects attention and behavior
This project looks at slow, large-scale brain activity and smaller circuit signals to learn how they relate to attention, watching movies, and rest in humans and closely related primates.
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Slow brain rhythms that shape attention and mind-wandering
Using electrodes placed inside the human brain, researchers are measuring how slow shifts in brain activity influence whether you focus on the outside world or on your own thoughts.
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Slow brain activity and how it shapes attention, arousal, and behavior
This project looks at how slow changes in brain activity relate to attention, alertness, and behavior in healthy adults using brain scans and body sensors.
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How very slow brain activity shapes thinking, attention, and mood
This project looks at how very slow changes in brain activity affect attention, mood, and everyday thinking in adults.
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CA2 hippocampal region and epilepsy in mice
This grant funds research on how a specific hippocampal area called CA2 contributes to drug‑resistant epilepsy in mouse models, with the aim of finding new ways to reduce seizures.
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Lifespan brain, body, and behavior resource for schizophrenia
This project is building a large open database of brain scans, physiological recordings, and behavioral information from people with schizophrenia and community volunteers across the lifespan.
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Finding the best times while awake to change memories
This project tests whether specific times and mental states while awake can make memories stronger or weaker for people with anxiety or age-related memory problems.
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How sex affects immune cells' role in adolescent brain wiring
Researchers are looking at how male and female adolescent brain immune cells called microglia help shape prefrontal brain connections, with implications for teens at risk for psychiatric conditions.
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Mossy cells' role in temporal lobe epilepsy
This project looks at how a specific brain cell called a mossy cell affects seizure damage and ongoing seizures in people with temporal lobe epilepsy.
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Investigating how sex differences affect brain cell interactions during adolescence
This study is looking at how brain immune cells called microglia interact with nerve cells during adolescence, a key time for brain growth, to see how these interactions affect thinking and behavior, especially since boys and girls may experience this differently.
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Understanding how the brain detects unusual visual information
This study looks at how the brain of mice notices unexpected visual changes, which could help us understand why some people have trouble processing what they see due to certain brain conditions.
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Understanding brain rhythms in aging and Alzheimer's disease
This work explores how brain rhythms, which are important for memory, change with age and Alzheimer's disease, and looks for ways to improve them.
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How the brain spots unexpected visual changes
Researchers will use mouse experiments to map the brain circuits that notice unexpected sights to better understand visual processing differences linked to autism.
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Investigating brain and behavior in older adults with schizophrenia
This study is looking at how schizophrenia affects older adults by gathering information about their brain activity, physical health, and behaviors, to better understand things like aggression, suicidal thoughts, and loneliness, and the results will be shared to help improve care for others.
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Clozapine to prevent violent behavior in people with schizophrenia
This project compares clozapine to usual care to find out whether clozapine lowers the chance of violent acts in people with schizophrenia who are at higher risk.
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How prenatal alcohol changes CB1 brain signaling
Looking at whether alcohol exposure before birth changes a brain signaling system called CB1 and leads to lasting learning and social problems in children.
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How the primate brain processes sounds and combines information from different senses
This research aims to understand how the brain's auditory system processes sounds and integrates information from different senses, like what we see and hear, to help us focus on important things in our environment.
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Investigating the role of a specific brain area in epilepsy
This study is looking at a part of the brain called CA2 to see how it affects epilepsy, especially in people whose seizures don't respond to medication, and it hopes to find new ways to help those patients feel better.
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A resource for studying brain and behavior across different ages
This study is gathering brain and behavior information from people aged 6 to 85 to help us learn how our brains change as we get older, and the findings will be shared to support future research on mental health conditions.
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Hearing-related brain signal tests to guide schizophrenia drug development
This project develops animal versions of a hearing-related brain response (mismatch negativity) to help create better treatments for people with schizophrenia or at high risk for psychosis.
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Investigating brain wave patterns in Alzheimer's disease
This study is looking at unusual brain wave patterns in Alzheimer's disease to see if they can help us understand memory problems better and find new ways to improve memory, using special technology to track these patterns in mice.
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Investigating the role of mossy cells in temporal lobe epilepsy
This study is looking at special brain cells called mossy cells to see how they can both cause and help stop seizures in people with temporal lobe epilepsy, with the hope of finding new treatment options for those who don’t respond to current medications.
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Investigating brain activity changes in Alzheimer's disease
This study is looking at how certain brain activities in people with Alzheimer's disease might affect thinking and memory, and it will explore if stopping these activities can help improve brain function and lower harmful proteins in the brain.
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Improving animal monitoring for better brain and behavior research
This study is looking at how special cages that let researchers watch mice around the clock can help keep them healthy and happy, which is important for learning more about brain diseases like Alzheimer's and improving treatments for people.
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How a specific gene affects the production of brain cell waste removal particles
This study is looking at how a specific gene called APOE affects tiny particles that help keep brain cells healthy by removing waste, and it aims to help people understand how their genetics might influence brain health as they age or deal with neurodegenerative diseases.
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Investigating how alcohol affects brain signaling during pregnancy
This study is exploring how drinking alcohol during pregnancy affects the developing brain of babies, particularly looking at how it might cause long-term behavior issues, and it aims to find ways to prevent or lessen these effects.
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Using clozapine to reduce violence in people with schizophrenia
This study is looking at whether clozapine, a medication for schizophrenia, can help reduce the chances of violent behavior in people who are at high risk, and it’s for individuals with schizophrenia who might benefit from a new treatment option.
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Understanding how different brain circuits interact in the auditory system of primates
This study is looking at how different parts of the brain work together when primates listen to sounds and react to them, helping us understand how we hear and respond to what we hear in our everyday lives.
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Exploring how tiny vesicles in the brain affect Alzheimer's disease
This study is looking at tiny particles called mitovesicles that might help clean up harmful materials in the brains of people with Alzheimer's disease, and it aims to find new ways to understand and treat the condition.
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