Dynamic brain circuits in primates: how hearing, multisensory cues, and memory work together
Official title: Dynamic circuit motifs underlying multimodal interactions in primate auditory cortex
Funded at Nathan S. Kline Institute for Psych Res · NIH-11374904 · Data updated 2026-11-12
Researchers are studying how the primate brain processes sounds alongside sights, eye movements, and memory to understand natural, real-world listening and behavior.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nathan S. Kline Institute for Psych Res NIH-funded |
| Lab location | 1 site (Orangeburg, United States) |
| Project start | September 16, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $632,935 |
| NIH project number | 5R01DC019979-05 |
| Project ID | NIH-11374904 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with auditory processing or attention-related challenges may benefit from future translational work informed by these findings.
✕Less likely to help
Healthy individuals without auditory or attentional difficulties may not receive direct benefits from this basic science project.
What this research studies
This grant aims to map how different brain circuits in primates carry information during natural listening and seeing tasks, using multisite recordings to capture driving versus modulatory signals. The study will track auditory cortex activity while animals engage in natural behaviors, such as looking around and recalling memories, to reveal how perception and action are coordinated. By comparing human and nonhuman primates, the project seeks to identify circuit motifs that support real-world listening and multisensory integration. Results could inform how we understand attention, perception, and memory in everyday environments.
Why it matters
Potential benefit: Understanding these brain circuits could lead to better interventions for hearing and attention difficulties, especially in complex, real-world settings.
How similar studies have gone: Previous similar approaches have begun to reveal how driving and modulatory circuits coordinate in the brain, with growing evidence of multisensory integration.
Where this research is happening
-
Nathan S. Kline Institute for Psych Res
Orangeburg, United States Active
Researchers
- Principal investigator: O'connell, Monica Noelle — Nathan S. Kline Institute for Psych Res
- Study coordinator: O'connell, Monica Noelle
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.