Lifespan brain, body, and behavior resource for schizophrenia

A Schizophrenia Extension Study for the NKI Rockland Sample II project: An Open Resource of Multimodal Brain, Physiology & Behavior from a Community Lifespan Sample

NIH-funded research Nathan S. Kline Institute for Psych Res · NIH-11305314

This project is building a large open database of brain scans, physiological recordings, and behavioral information from people with schizophrenia and community volunteers across the lifespan.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNathan S. Kline Institute for Psych Res NIH-funded
Lab location1 site (Orangeburg, United States)
Project IDNIH-11305314 on NIH RePORTER

What this research studies

You would join an extension of the NKI Rockland lifespan project that collects EEG, fMRI, physiological recordings, and behavioral tests from people with schizophrenia and community participants. The team will share both raw and processed data plus analysis tools openly so researchers worldwide can use them. Data include cognitive tests, symptom measures, health and lifestyle information, and measures tied to aggression, urgency, loneliness, and suicidality. By combining many participants across ages, the resource aims to make it easier to find brain and behavioral markers that could guide future care.

Who could benefit from this research

Good fit: Ideal participants include people diagnosed with schizophrenia across the lifespan and community volunteers willing to undergo brain imaging, physiological recordings, and behavioral assessments.

Not a fit: People seeking immediate clinical treatment rather than research participation, or those unable to tolerate MRI/EEG procedures, are unlikely to receive direct medical benefit from participation.

Why it matters

Potential benefit: If successful, the open resource could help researchers identify brain and behavioral markers that lead to earlier detection and more targeted treatments for people with schizophrenia.

How similar studies have performed: Large open neuroimaging projects like the original NKI Rockland Sample and the Human Connectome Project have supported discoveries, but a multimodal lifespan resource focused on schizophrenia is less common.

Where this research is happening

Orangeburg, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.