Lifespan brain, body, and behavior resource for schizophrenia
Official title: A Schizophrenia Extension Study for the NKI Rockland Sample II project: An Open Resource of Multimodal Brain, Physiology & Behavior from a Community Lifespan Sample
Funded at Nathan S. Kline Institute for Psych Res · NIH-11305314 · Data updated 2026-11-12
This project is building a large open database of brain scans, physiological recordings, and behavioral information from people with schizophrenia and community volunteers across the lifespan.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nathan S. Kline Institute for Psych Res NIH-funded |
| Lab location | 1 site (Orangeburg, United States) |
| Project start | July 15, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2026 |
| Award (this year) | $820,402 |
| NIH project number | 5R01MH137769-03 |
| Project ID | NIH-11305314 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants include people diagnosed with schizophrenia across the lifespan and community volunteers willing to undergo brain imaging, physiological recordings, and behavioral assessments.
✕Less likely to help
People seeking immediate clinical treatment rather than research participation, or those unable to tolerate MRI/EEG procedures, are unlikely to receive direct medical benefit from participation.
What this research studies
You would join an extension of the NKI Rockland lifespan project that collects EEG, fMRI, physiological recordings, and behavioral tests from people with schizophrenia and community participants. The team will share both raw and processed data plus analysis tools openly so researchers worldwide can use them. Data include cognitive tests, symptom measures, health and lifestyle information, and measures tied to aggression, urgency, loneliness, and suicidality. By combining many participants across ages, the resource aims to make it easier to find brain and behavioral markers that could guide future care.
Why it matters
Potential benefit: If successful, the open resource could help researchers identify brain and behavioral markers that lead to earlier detection and more targeted treatments for people with schizophrenia.
How similar studies have gone: Large open neuroimaging projects like the original NKI Rockland Sample and the Human Connectome Project have supported discoveries, but a multimodal lifespan resource focused on schizophrenia is less common.
Where this research is happening
-
Nathan S. Kline Institute for Psych Res
Orangeburg, United States Active
Researchers
- Principal investigator: Javitt, Daniel C. — Nathan S. Kline Institute for Psych Res
- Study coordinator: Javitt, Daniel C.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.