Investigating brain wave patterns in Alzheimer's disease
High frequency oscillations in Alzheimer's disease
This study is looking at unusual brain wave patterns in Alzheimer's disease to see if they can help us understand memory problems better and find new ways to improve memory, using special technology to track these patterns in mice.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nathan S. Kline Institute for Psych Res NIH-funded |
| Lab location | 1 site (Orangeburg, United States) |
| Project ID | NIH-11058153 on NIH RePORTER |
What this research studies
This research focuses on understanding abnormal brain wave patterns, specifically high frequency oscillations (HFOs), in Alzheimer's disease. By using advanced EEG technology, the study aims to identify these oscillations as potential biomarkers for the disease and explore their role in memory impairment. The research will involve monitoring these brain wave patterns in mouse models to see how they change over time and how they might be manipulated to improve memory function. This approach could lead to new insights into the progression of Alzheimer's and potential therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals at risk for Alzheimer's disease or those in the early stages of cognitive decline.
Not a fit: Patients with advanced Alzheimer's disease or those without cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new non-invasive biomarkers for early detection of Alzheimer's disease and innovative methods to enhance memory function.
How similar studies have performed: While the investigation of high frequency oscillations in Alzheimer's is a relatively novel approach, similar studies in epilepsy have shown promising results.
Where this research is happening
Orangeburg, United States
- Nathan S. Kline Institute for Psych Res — Orangeburg, United States (Active)
Researchers
- Principal investigator: Lisgaras, Christos Panagiotis — Nathan S. Kline Institute for Psych Res
- Study coordinator: Lisgaras, Christos Panagiotis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.