Investigating brain and behavior in older adults with schizophrenia
A Schizophrenia Extension Study for the NKI Rockland Sample II project: An Open Resource of Multimodal Brain, Physiology & Behavior from a Community Lifespan Sample
['FUNDING_R01'] · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · NIH-11138750
This study is looking at how schizophrenia affects older adults by gathering information about their brain activity, physical health, and behaviors, to better understand things like aggression, suicidal thoughts, and loneliness, and the results will be shared to help improve care for others.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NATHAN S. KLINE INSTITUTE FOR PSYCH RES (nih funded) |
| Locations | 1 site (ORANGEBURG, UNITED STATES) |
| Trial ID | NIH-11138750 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding schizophrenia in older adults by creating a comprehensive database that includes brain imaging, physiological data, and behavioral assessments. It utilizes advanced technologies like EEG and fMRI to explore the neural mechanisms associated with the disorder. By analyzing data from a large community sample, the study aims to identify risk factors for aggression and suicidality, as well as the impact of loneliness on health outcomes. The findings will be shared openly to facilitate further clinical investigations.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 85 and older who have been diagnosed with schizophrenia.
Not a fit: Patients without a diagnosis of schizophrenia or those younger than 85 years old may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for older adults suffering from schizophrenia.
How similar studies have performed: Previous research has shown success in using multimodal approaches to study schizophrenia, indicating that this method could yield valuable insights.
Where this research is happening
ORANGEBURG, UNITED STATES
- NATHAN S. KLINE INSTITUTE FOR PSYCH RES — ORANGEBURG, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JAVITT, DANIEL C. — NATHAN S. KLINE INSTITUTE FOR PSYCH RES
- Study coordinator: JAVITT, DANIEL C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.