Understanding how the brain detects unusual visual information
Circuits for deviance detection in V1
['FUNDING_R01'] · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · NIH-11199823
This study looks at how the brain of mice notices unexpected visual changes, which could help us understand why some people have trouble processing what they see due to certain brain conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NATHAN S. KLINE INSTITUTE FOR PSYCH RES (nih funded) |
| Locations | 1 site (ORANGEBURG, UNITED STATES) |
| Trial ID | NIH-11199823 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain's primary visual cortex (V1) responds to visual stimuli that deviate from expected patterns. By studying the neural activity in mice, the researchers aim to uncover the underlying circuitry involved in this 'deviance detection' process. The study utilizes advanced genetic and optical tools to explore how different types of neurons interact to enhance the brain's ability to recognize important visual changes. Insights gained could help understand visual processing deficits in various neurological and psychiatric disorders.
Who could benefit from this research
Good fit: Ideal candidates for potential benefit include individuals with neurological or psychiatric disorders that affect visual processing.
Not a fit: Patients without any neurological or psychiatric conditions affecting visual perception may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of visual processing issues in individuals with neurological and psychiatric conditions.
How similar studies have performed: Previous research has shown promising results in understanding deviance detection in animal models, suggesting potential for similar insights in human conditions.
Where this research is happening
ORANGEBURG, UNITED STATES
- NATHAN S. KLINE INSTITUTE FOR PSYCH RES — ORANGEBURG, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HAMM, JORDAN P — NATHAN S. KLINE INSTITUTE FOR PSYCH RES
- Study coordinator: HAMM, JORDAN P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.