Sponsor or institution
Clinical trials and research at Memorial Sloan Kettering Cancer Center
As of November 12, 2026, Find a Trial lists 311 clinical trials run by Memorial Sloan Kettering Cancer Center that are recruiting, at sites in 15 countries (most in United States (310), Nigeria (3), Netherlands (2)). 9 were first registered in the last 30 days. By phase: Phase 2 (107), Phase 1 (41), Phase 1/2 (16), Phase 3 (10). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 311Clinical trials
- 9New in 30 days
- 15Countries
Newest trials
All recruiting trials (newest 150 of 311)
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Retifanlimab after chemoradiation for anal cancer
This study tests whether retifanlimab can help people with anal squamous cell carcinoma who have completed chemoradiation and still have residual disease.
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Different skin care approaches to prevent skin reactions after mastectomy radiation
This study tests three standard skin care methods to see which best prevents radiation dermatitis in people who had a mastectomy and are receiving post-mastectomy radiation therapy.
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Graft-versus-host disease after stem cell transplant: testing LBP-MARCO with ruxolitinib
We are testing whether combining LBP-MARCO with ruxolitinib is safe for adults with GVHD after a stem cell transplant.
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68Ga-FAPI PET/MRI imaging to see if it can track breast cancer response to chemotherapy
This study tests whether a new imaging scan, 68Ga-FAPI PET/MRI, can show how well invasive breast cancer responds to neoadjuvant chemotherapy in adults.
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Can we skip radiation after lumpectomy for low-risk HER2-positive breast cancer?
This study tests whether patients who had breast-conserving surgery and low-risk HER2-positive breast cancer can safely skip radiation therapy while receiving HER2-targeted treatment.
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Combination of ivermectin with standard skin-protective care for daraxonrasib-related skin toxicity in pancreatic cancer
This study tests whether adding ivermectin to standard preventive skin care helps people with pancreatic cancer who develop skin side effects from daraxonrasib.
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AI tool helps dermatologists decide if a skin lesion could be melanoma
A computer tool called DEXI tested with DermaGraphix Visualizer helps dermatologists see if a skin lesion might be melanoma and aims to reduce unnecessary biopsies.
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Stopping ropeg-interferon in some polycythemia vera patients after responding to treatment
This study tests whether some people with polycythemia vera who respond to ropeg-interferon can safely stop the therapy.
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Your Kidney Cancer Immunotherapy: How You Get It and If Labs Can Be At Home
This study tests whether people with kidney cancer prefer intravenous or subcutaneous immunotherapy and whether at‑home lab draws plus telehealth visits before treatment are practical.
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Music-Based Therapy for Anxiety in Cancer Patients: AI Songwriting vs. Music Listening
This study tests two music-based approaches to see if they can reduce anxiety in adults with advanced cancer who are in treatment.
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Ear nerve stimulation to help eye inflammation
A small early study will test whether a gentle ear nerve stimulator can reduce eye inflammation in adults with inflammatory eye conditions.
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Adding 2141-V11 to standard therapy for advanced esophageal, gastric, or gastroesophageal junction cancer
This study tests whether adding the drug 2141-V11 to standard anti-PD-1 therapy (with or without 5-FU) is safe for adults with advanced or metastatic esophageal, gastric, or gastroesophageal junction adenocarcinoma.
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SX-682 with proton craniospinal irradiation for leptomeningeal disease
This study tests whether adding SX-682 to proton craniospinal irradiation can be safe and helpful for adults with leptomeningeal disease from melanoma or NSCLC.
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SRS Before Surgery for Brain Metastases to Try Better Surgical Outcomes
This study tests whether giving stereotactic radiosurgery to a single brain metastasis before its surgical removal can reduce cancer spread during surgery and improve recovery.
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Armored DLL3-SAVVYZ-IL18 CAR T cells for DLL3+ cancers
Aims to see if DLL3-SAVVYZ-IL18 CAR T cells can be safely given to people with DLL3-positive cancers, including certain small cell lung cancers and other neuroendocrine tumors.
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Making Cents of Medical Costs for young adult cancer survivors
A digital program test to see if the Making Cents of Medical Costs helps young adults (18-39) who have completed cancer treatment manage financial issues related to care.
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Romosozumab for bone formation in people with breast cancer and osteoporosis
This study tests whether romosozumab can help build bone in adults with metastatic breast cancer that has spread to bone and who also have osteoporosis.
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Brief Behavioral Activation for cancer survivors 65+
This study tests whether a short behavioral-activation therapy delivered by phone or video can help reduce depression and anxiety and improve well-being in English- or Spanish-speaking cancer survivors aged 65 and older.
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Can older adults with breast cancer tolerate a dense CMF chemo schedule
This study tests whether giving a condensed CMF chemotherapy regimen is feasible for people 70 and older with breast cancer.
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Radiation therapy options for high-risk prostate cancer
This trial tests different ways of giving radiation therapy to see which balance best controls the cancer with the fewest side effects in men with high-risk, non-metastatic prostate cancer.
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Luspatercept for anemia due to chronic kidney disease
This study tests whether luspatercept can raise hemoglobin levels in people with anemia caused by CKD and whether it is safe.
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Lung Cancer Risk in Never-Smokers
This study tests factors that might raise the chance of lung cancer in people who have never smoked.
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177Lu-DTPA-omburtamab for kids with recurring medulloblastoma or brain/CNS metastases
This study tests whether 177Lu-DTPA-omburtamab can be safely given to children and adolescents with recurrent or refractory medulloblastoma or cancer that has spread to the CNS.
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New total-body PET scanner test in people with NSCLC, head and neck cancer, and prostate cancer
Researchers are testing a new total-body PET scanner called Biograph Vision Quadra to see if it provides clearer images and more information than standard PET/CT in people with certain cancers.
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ELI-002 7P with or without Tislelizumab added to mFOLFIRINOX for pancreatic cancer
A small study tests whether adding ELI-002 7P, with or without tislelizumab, to neoadjuvant mFOLFIRINOX is safe and may help patients with resectable or borderline resectable pancreatic ductal adenocarcinoma that has a KRAS mutation.
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CRD3874-SI in People with Leukemia
A small early-stage study tests CRD3874-SI to see if it is safe for adults with relapsed or refractory acute myeloid leukemia.
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Urine test to help spot colorectal cancer and polyps
This study tests a urine-based 3-metabolite biosensor to see if it can detect colorectal cancer and precancerous polyps in adults in Ghana, Tanzania, and South Africa.
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Side Effects and Resource Navigation Program for Cancer Patients
This program tests whether a navigation service helps adults with kidney, bladder, breast, or lung cancer manage immunotherapy better than usual care.
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MSK-TCR5 in adults with advanced solid tumors that have KRAS/HRAS/NRAS G12D
This study tests MSK-TCR5 to see if it is safe for adults with advanced solid tumors carrying a KRAS, HRAS, or NRAS G12D mutation.
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Lower-dose radiation to parts of the prostate for some men with prostate cancer
This study tests whether a smaller amount of radiation aimed at specific parts of the prostate can reduce side effects compared with giving the full prostate the same dose.
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Cadonilimab with chemotherapy for gastric or GEJ cancer
This trial tests whether adding cadonilimab to standard chemotherapy is safe and effective for adults with locally advanced or resectable gastric or GEJ cancer.
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Tepotinib plus Ivonescimab for MET exon 14–positive NSCLC
This study tests whether a combination of tepotinib and ivonescimab is safe and helps people with MET exon 14–skipping non-small cell lung cancer.
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Malignant Colorectal Polyp Registry: What Happens After Early Colorectal Cancer is Removed
This registry follows adults who had a single early colorectal cancer polyp removed endoscopically to see how often cancer comes back or spreads and to understand how decisions about further surgery or surveillance are made.
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MRI scan for detecting pancreatic cancer in people at high risk
This study tests a dedicated pancreas MRI (MRP) tool to see if it helps find pancreatic cancer earlier in people with a strong family or genetic risk.
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Ivonescimab after SBRT for early-stage NSCLC
This study tests whether adding ivonescimab after standard SBRT helps people with early-stage non-small cell lung cancer.
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High-Fiber Plant-Based Diet in People with Clonal Hematopoiesis
This study tests whether a high-fiber plant-based diet can improve quality of life for adults with clonal hematopoiesis.
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Cord blood transplant for children and young adults with blood cancers.
This study will test whether a cord blood transplant given as a first or second transplant can help children and young adults with leukemia, myelodysplasia, or lymphoma who lack a matched donor.
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Cardiac MRI for catheter-associated right atrial clots in adults with cancer
This will see if cardiac MRI (CMR) can accurately identify and describe right atrial clots that form around central venous catheters in adults with cancer.
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Irreversible electroporation (IRE) versus standard radiation boost for intermediate-risk prostate cancer
The trial will test whether adding an irreversible electroporation (IRE) boost works as well as the standard radiation boost for people with intermediate-risk prostate cancer receiving SBRT.
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Mirdametinib for people with central nervous system tumors
This trial tests whether mirdametinib is safe and can help adults with central nervous system tumors, including glioma and neurohistiocytosis.
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Ivonescimab with chemotherapy and stereotactic radiosurgery for NSCLC brain metastases
This trial tests whether adding the experimental drug ivonescimab to standard chemotherapy and stereotactic radiosurgery helps people with non-small cell lung cancer that has spread to the brain.
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Ivonescimab with datopotamab deruxtecan or osimertinib for EGFR‑mutant non‑small cell lung cancer
This trial will test whether combining ivonescimab with datopotamab deruxtecan or with osimertinib is safe and helps people with metastatic EGFR‑mutant non‑small cell lung cancer who have already received third‑generation EGFR inhibitors and chemotherapy.
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BMS-986504 combined with standard treatments for certain metastatic MTAP‑deleted solid tumors
This trial tests whether adding the experimental drug BMS‑986504 to standard cancer treatments is safe for people with advanced MTAP‑deleted mesothelioma, gastroesophageal, or urothelial cancers.
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Ivonescimab treatment for people with leiomyosarcoma
We will try ivonescimab in adults with advanced or unresectable leiomyosarcoma to see if it controls the cancer and causes few or mild side effects.
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Methylprednisolone Before Major Liver Surgery
This trial tests whether giving methylprednisolone before major liver surgery helps reduce postoperative complications like infections and long hospital stays for adults having hepatectomy.
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Pre-surgery hormone therapy to lower positive margins in lobular breast cancer
This Phase 2 trial tests whether giving endocrine (hormone) therapy before breast-conserving surgery can reduce the chance of cancer at the edges of the removed tissue in postmenopausal people with ER+/HER2- invasive lobular breast cancer.
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Gefitinib, trametinib, disulfiram, and sunitinib added to standard chemotherapy for metastatic osteosarcoma
This study tests whether adding gefitinib, trametinib, disulfiram, and sunitinib to standard chemotherapy helps people with newly diagnosed metastatic osteosarcoma.
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ctDNA-guided sequential anti-HER2 therapy with CNS prophylaxis for HER2-positive metastatic breast cancer
This trial will test whether using regular ctDNA blood tests to guide stepping up or down sequential anti-HER2 treatments, together with local therapies and measures to protect the brain and spinal cord, can produce long-lasting remission for people with HER2-positive stage IV breast cancer.
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Elranatamab plus cyclophosphamide for relapsed/refractory multiple myeloma with high-risk features
This will test whether adding cyclophosphamide to elranatamab helps people with relapsed or refractory multiple myeloma who have risk factors that might make elranatamab alone less effective.
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Support program to improve quality of life for Chinese cancer patients and survivors
This program will try different mixes of education, counseling, and peer support to see if they help Mandarin-speaking adults with cancer or who have finished treatment feel better.
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Gastric preconditioning before esophagectomy for patients at high risk of anastomotic leak
This registry will see if gastric preconditioning by percutaneous angioembolization before esophagectomy changes how often anastomotic leaks happen in people with esophageal cancer who are at high risk.
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Comparing two OCT scanners for people with ocular tumors
This will try two different OCT imaging devices to see which makes clearer eye images for adults with ocular tumors.
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Tibetree topical herbal plasters for people using opioids for cancer pain
This trial will try Tibetree topical herbal plasters together with prescribed opioids to see if they reduce localized cancer-related pain for adults who are currently taking short-term oral opioids.
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Obecabtagene autoleucel as consolidation for B‑cell acute lymphoblastic leukemia in MRD‑negative remission
This study will test whether a single infusion of obecabtagene autoleucel can help adults with CD19+ B‑cell acute lymphoblastic leukemia who are in their first MRD‑negative complete remission stay in remission longer.
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Blood test and software to guide treatment for venous thromboembolism
This project tests whether a blood-based ctDNA test combined with a software risk score can predict if VTE will come back in adults with cancer-associated DVT or PE who have finished 3–12 months of anticoagulation.
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Combination ivosidenib with azacitidine and venetoclax followed by ivosidenib maintenance for IDH1‑mutated AML
This trial will test whether giving ivosidenib with azacitidine and venetoclax, then continuing ivosidenib alone, helps people aged 60 and older with newly diagnosed IDH1‑mutated acute myeloid leukemia.
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Registry for people with symptomatic bone metastases
This registry collects health information from adults with symptomatic bone metastases who need treatment for painful or unstable bone lesions to learn more about outcomes and care.
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Nerve effects of enfortumab vedotin in people with urothelial cancer
We will see how nerve testing and patient-reported symptoms change in adults with urothelial cancer who are starting enfortumab vedotin.
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Ruxolitinib to prevent graft-versus-host disease after allogeneic stem cell transplant
This trial will test whether adding ruxolitinib to standard drugs better prevents chronic graft-versus-host disease in adults receiving an allogeneic stem cell transplant for blood cancers.
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Revumenib with Mezigdomide for relapsed or refractory acute leukemia
This trial will test whether combining revumenib and mezigdomide is safe for people aged 12 and older with relapsed or refractory acute leukemia that has KMT2A, NUP98, or NPM1 genetic changes.
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Decision tool for people considering breast reconstruction surgery.
Researchers will try a decision tool called RECONJOINT to help adults with breast cancer or a genetic predisposition decide about post-mastectomy breast reconstruction.
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BIO 300 with thoracic radiation for early-stage non-small cell lung cancer and interstitial lung disease
This trial will test whether adding BIO 300 to thoracic radiation lowers the chance of pneumonitis in people with stage I–II non-small cell lung cancer who also have interstitial lung disease.
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Multiparametric ultrasound to examine vaginal tissue in people with endometrial cancer
We will test whether multiparametric ultrasound can spot changes in vaginal tissue before and after intravaginal radiotherapy in people treated for stage I–II endometrial cancer.
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Measuring operator radiation exposure during image-guided robotic bronchoscopy
This study will measure how much radiation bronchoscopists are exposed to while performing standard image-guided robotic-assisted bronchoscopy on adult patients with a single lung lesion.
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Gabapentin for perioperative pain control in mastectomy
This trial will test whether a pre-operative dose of gabapentin reduces pain and opioid use for adults 18–65 having ambulatory mastectomy at Memorial Sloan Kettering.
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Isoquercetin for people with ovarian cancer
This trial will test whether taking isoquercetin along with first-line chemotherapy can lower blood markers tied to blood clot risk in people with ovarian cancer.
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Factors linked to breast cancer risk and outcomes
This project will collect blood, tissue, and survey information from women with suspicious breast findings or new breast cancer seen at MSK to see which factors are linked to risk and outcomes.
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ctDNA testing to guide maintenance immunotherapy decisions for advanced or recurrent endometrial cancer.
This project will test whether a blood ctDNA test can help people with MMR‑D/MSI‑H advanced or recurrent endometrial cancer and their doctors decide whether to continue immunotherapy after one year of standard chemotherapy plus an immune checkpoint inhibitor.
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Multiparametric ultrasound imaging for pancreatic risk screening and thyroid nodules
This project will try multiparametric ultrasound (mpUS) to see if it gives clearer pictures of pancreatic tissue for people at high risk for pancreatic cancer and of thyroid nodules for people being evaluated for those lumps.
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Voice monitoring for side effects during CAR T-cell therapy
This project will test whether twice-daily smartphone voice recordings and brief daily neurologic checks can spot early neurologic side effects in adults receiving FDA-approved CAR T-cell therapy for non-Hodgkin lymphoma or multiple myeloma.
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Pirtobrutinib combined with venetoclax and rituximab for Waldenström's macroglobulinemia
This treatment tries combining pirtobrutinib, venetoclax, and rituximab in people newly diagnosed with Waldenström's macroglobulinemia (WM)/lymphoplasmacytic lymphoma to see if it controls the disease.
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Botensilimab plus balstilimab followed by balstilimab for colorectal cancer with detectable ctDNA after surgery and chemotherapy
This trial tests whether giving botensilimab with balstilimab, then continuing balstilimab alone, helps people with microsatellite-stable colorectal cancer or colorectal liver metastases who still have detectable ctDNA after surgery and chemotherapy.
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High-fiber, plant-based diet during initial treatment for multiple myeloma
The team will test whether following a high-fiber, plant-based diet during initial chemotherapy helps people newly diagnosed with multiple myeloma have better treatment responses and quality of life.
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Meaning-Centered Therapy for Latinos for adults with advanced cancer
This study tests whether Meaning-Centered Psychotherapy for Latinos (MCP-L) can reduce anxiety and depression and improve quality of life compared with CBT in Spanish-speaking adults with advanced cancer.
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177Lu-PSMA-617 treatment for IDH‑wildtype gliomas
This trial will test whether the radiopharmaceutical 177Lu-PSMA-617 is safe for adults with IDH‑wildtype gliomas who have completed standard surgery and radiation.
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Fludarabine dosing for children and young adults with B-cell acute lymphoblastic leukemia
This trial will test whether pharmacokinetic (PK)-targeted fludarabine dosing before tisagenlecleucel CAR T-cell therapy helps children and young adults with relapsed or refractory B‑cell ALL more than standard fludarabine dosing.
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Local antibiotic beads to prevent infection after breast tissue expander placement
This study will test whether placing biodegradable antibiotic beads at the time of immediate prepectoral tissue expander reconstruction lowers infection and seroma risk for adult women having mastectomy reconstruction.
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Electronic nose (breathprint) to track treatment response in non-small cell lung cancer
This trial will test whether an electronic nose breath test can detect chemical changes in the breath of adults with non-small cell lung cancer before and after neoadjuvant therapy or surgery.
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One-time 60-minute counseling session to reduce depression, anxiety, and distress in people with breast cancer
This program will test whether a single 60-minute counseling session can help reduce depression, anxiety, and distress for adults with breast cancer who are waiting for outpatient psychotherapy.
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Questionnaires for Adolescents and Young Adults Living with Cancer
This project will test whether the PRO-AYA patient-reported outcome questionnaires, including a Spanish version, are clear and useful for adolescents and young adults with cancer.
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Elacestrant alone or with abemaciclib for ER-positive advanced or recurrent endometrial cancer
This trial will test whether elacestrant by itself or paired with abemaciclib helps people with advanced or recurrent estrogen receptor–positive endometrial cancer who have had prior platinum chemotherapy and a PD‑1 inhibitor.
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How people make decisions about prostate cancer risk
This study will test how men assigned male at birth aged 45–70 with BRCA1/2 mutations respond to genetic risk modifier testing and whether it changes their prostate cancer screening choices and feelings about care.
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Family COMIDA — helping Hispanic families choose healthier foods to prevent and reduce obesity
This program tests family-centered support (parent counseling, weekly phone coaching, monthly group sessions, and child education) to help Hispanic parents/caregivers and their 8–12-year-old children prevent or reduce obesity.
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MB-CART19.1 cellular therapy for people with central nervous system lymphoma
This will test whether MB-CART19.1 cellular therapy is safe and helps adults with relapsed or refractory primary or secondary central nervous system lymphoma.
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Tongue strength and endurance testing with the IOPI in people with oral tongue cancer
This will test tongue strength and endurance using a small device called the IOPI in adults scheduled for primary surgery for oral tongue cancer.
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Distress screening and referral program for adults with newly diagnosed solid tumors
This program will try a distress screening and referral process using the NCCN Distress Thermometer to help English- and Spanish-speaking adults newly diagnosed with solid tumors get connected to mental health support.
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Tarlatamab for DLL3-positive metastatic prostate cancer
This study will try tarlatamab in adults with metastatic, DLL3-positive prostate cancer that has relapsed or not responded to previous treatments.
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Teclistamab plus mezigdomide for relapsed or refractory multiple myeloma
This trial will try a combination of teclistamab and mezigdomide in people with relapsed or refractory multiple myeloma who have had at least two prior therapies including a proteasome inhibitor, an IMiD, and an anti‑CD38 antibody.
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Daratumumab followed by teclistamab with RVd for newly diagnosed multiple myeloma
This test tries whether switching from daratumumab plus RVd to teclistamab plus RVd after three treatment cycles is safe for people with newly diagnosed multiple myeloma.
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Ma-Zi-Ren-Wan (MZRW) herbal treatment for constipation in cancer survivors
This will see if the herbal formula Ma-Zi-Ren-Wan (MZRW) helps relieve functional constipation in adult cancer survivors compared with a placebo.
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Pembrolizumab for ultra-rare sarcomas
This trial will test whether pembrolizumab can help people with certain ultra-rare sarcomas and cause only mild side effects.
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Epcoritamab plus ibrutinib for central nervous system lymphoma
This trial tests whether combining epcoritamab and ibrutinib is safe and tolerable for adults with relapsed or refractory primary or secondary central nervous system lymphoma.
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Sacituzumab govitecan plus cetuximab for recurrent or metastatic head and neck squamous cell cancer
This trial will test whether combining sacituzumab govitecan with cetuximab works and is safe for people whose head and neck squamous cell cancer has returned or spread after prior immunotherapy.
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Surgery and focused radiation plus HER2-targeted therapy for oligometastatic HER2-positive breast cancer
This will test whether adding surgery and precise radiation to standard HER2-targeted treatment helps people with oligometastatic HER2-positive breast cancer whose disease is controlled after initial therapy.
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Telehealth music therapy for cognitive difficulties in blood cancer survivors
This program will test whether telehealth music therapy can help adults who survived leukemia, lymphoma, or myeloma and who are having trouble with memory, attention, or thinking.
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Revaree Plus for vaginal dryness in people with breast cancer
This trial will test whether Revaree Plus can improve vaginal dryness and related discomfort in adults with hormone-receptor–positive stage 0–III breast cancer who are on tamoxifen, aromatase inhibitors, or SERMs.
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How exercise relates to health and cancer outcomes in adult survivors
This project will see if exercising after treatment is linked to cancer outcomes and other health events in adults who have finished primary cancer therapy.
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Reduced-dose radiation therapy for people with follicular or marginal zone lymphoma
This trial will test whether very low-dose radiation controls stage I–II follicular or marginal zone lymphoma as well as standard-dose radiation while causing fewer side effects.
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Combining cytokine-induced memory-like natural killer cells with atezolizumab for relapsed or refractory AML
This trial will test whether giving cytokine-induced memory-like natural killer cells together with atezolizumab is safe and might help adults with relapsed or refractory acute myeloid leukemia.
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Time-restricted eating for adult survivors of childhood cancer
This study will test whether time-restricted eating combined with regular coaching helps adult survivors of childhood cancer lose weight and lower heart and metabolic risk compared with standard education and monthly weigh-ins.
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Belumosudil to prevent graft-versus-host disease after a stem cell transplant
This will test whether adding the drug belumosudil to standard prevention lowers the risk of graft-versus-host disease in adults with blood cancers after a stem cell transplant.
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Alectinib plus duvelisib for ALK-positive anaplastic large cell lymphoma
This trial tests whether combining alectinib with duvelisib is a safe, time-limited treatment for people with relapsed or refractory ALK-positive anaplastic large cell lymphoma.
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Using local anesthesia during prostate biopsies to reduce pain
This study tests whether using local anesthesia with IV sedation during prostate biopsies can help reduce pain and improve recovery for patients.
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Lower radiation therapy with chemotherapy for HPV-positive throat cancer
This study is testing if giving lower doses of radiation along with chemotherapy can effectively treat patients with HPV-positive throat cancer just as well as the usual higher doses of radiation.
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Using IgPro20 to prevent infections in patients with multiple myeloma and low immunoglobulin levels
This study is testing if IgPro20 can help prevent infections in people with multiple myeloma and low immune levels who are receiving certain treatments.
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Hospital-at-Home program for patients receiving Tarlatamab
This study is testing if a Hospital-at-Home program can help adults with advanced small cell lung cancer who are getting tarlatamab feel better while being monitored from home instead of staying in the hospital.
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Improving telehealth delivery of cancer care at home
This study is testing if using telehealth can make cancer care at home better for patients with breast and prostate cancer, so they don’t have to go to the hospital as often.
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Testing new drug combinations for glioblastoma treatment
This study is testing new combinations of drugs to see if they can safely help people with recurrent or newly diagnosed glioblastoma, an aggressive type of brain cancer.
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Comparing treatments for non-muscle invasive bladder cancer
This study is testing a new treatment called nadofaragene firadenovec against standard options for adults with non-muscle invasive bladder cancer who haven’t had success with previous treatments.
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Testing ivonescimab for endometrial and cervical cancers
This study is testing a new drug called ivonescimab to see if it can help people with advanced endometrial and cervical cancers that haven't improved after other treatments.
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Using acupuncture to help women regain their menstrual cycle after chemotherapy
This study is testing if acupuncture can help women under 40 who lost their periods after chemotherapy get their menstrual cycles back.
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Testing Enfortumab Vedotin for Adenoid Cystic Carcinoma
This study is testing if a new drug called enfortumab vedotin can help people with advanced adenoid cystic carcinoma feel better when other treatments aren't an option.
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Using fluorescein sodium to assist in vulvectomy for extramammary Paget's disease
This study is testing if giving a special dye before surgery can help doctors find and remove cancerous cells more effectively in patients with extramammary Paget's disease.
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Testing mirdametinib with palbociclib for treating liposarcoma
This study is testing a new combination of two medications, mirdametinib and palbociclib, to see if they can help people with advanced liposarcoma feel better and improve their treatment options.
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Combination treatment for rectal adenocarcinoma using botensilimab and balstilimab
This study is testing a new combination treatment with botensilimab and balstilimab to see if it can help people with locally advanced rectal cancer feel better with fewer side effects than regular chemotherapy.
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Combining abemaciclib and cabozantinib for treating metastatic clear cell renal cell carcinoma
This study is testing a combination of two drugs, abemaciclib and cabozantinib, to see if they can safely help people with advanced clear cell kidney cancer.
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Acupuncture for joint pain in breast cancer survivors on hormonal therapy
This study is testing if acupuncture can help reduce joint pain in breast cancer survivors from Black, Asian, and Hispanic backgrounds who are on hormonal therapy.
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Testing valemetostat with atezolizumab for lung cancer treatment
This study is testing a new combination of medications, valemetostat and atezolizumab, to see if it can safely help people with extensive-stage small cell lung cancer who have had some success with earlier treatments.
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Evaluating sotorasib for treating brain tumors
This study tests if a drug called sotorasib can help adults with certain types of brain tumors before they have surgery or a biopsy.
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Using SER-155 to treat diarrhea in patients receiving immunotherapy
This study is testing if a new medication called SER-155 can help adults with severe diarrhea caused by immunotherapy feel better with fewer side effects.
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Understanding breast cancer risk factors and outcomes in Florida
This study is trying to understand the different risk factors and outcomes of breast cancer in men and women in Florida by collecting samples and survey information from new patients at breast clinics.
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Using azacitidine and venetoclax to treat acute myeloid leukemia before a stem cell transplant
This study is testing if the combination of azacitidine and venetoclax can help adults with acute myeloid leukemia stay cancer-free after a stem cell transplant.
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Combining ruxolitinib and ulixertinib for treating myelofibrosis
This study is testing if combining two medications, ruxolitinib and ulixertinib, can help people with myelofibrosis who haven't had enough relief from ruxolitinib alone.
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Treatment for Diffuse Large B-cell Lymphoma using Glofitamab
This study is testing a new combination of treatments for people with diffuse large B-cell lymphoma to see if it works better and has fewer side effects than current options.
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Treating brain metastasis in lung cancer with radiosurgery and osimertinib
This study is testing if adding a special type of radiation therapy to the lung cancer drug osimertinib can help people with brain metastases feel better and improve their treatment results.
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Testing blood for cancer DNA in patients with B-cell lymphoma
This study is testing if a blood test for cancer DNA can help identify patients with B-cell lymphoma who are at risk of having their cancer come back in the brain or spinal cord, even when other tests show no signs of it.
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Managing joint pain in breast cancer survivors
This study tests whether two different group therapy approaches can help breast cancer survivors manage joint pain from their medication and improve their overall well-being.
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Language interpretation solutions for breast cancer patients
This study is testing different ways to help Spanish- and Mandarin-speaking breast cancer patients communicate better with their doctors during appointments.
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Lung cancer screening for people with unexplained weight loss
This study is testing if people who have lost weight for no clear reason are more likely to have lung cancer and will use special scans and blood tests to find out.
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Comparing surgical techniques during bladder cancer surgery
This study is testing two different surgical methods for bladder cancer to see which one helps patients recover better and have fewer complications after surgery.
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Using cemiplimab and fianlimab before kidney cancer surgery
This study is testing whether giving two immunotherapy drugs before kidney cancer surgery can safely shrink tumors in patients with high-risk non-metastatic clear cell renal cell carcinoma.
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Preventing Adult T-cell Leukemia/Lymphoma in People with HTLV-1
This study is testing if a new drug called mogamulizumab can help prevent adult T-cell leukemia/lymphoma in adults who are infected with the HTLV-1 virus and are at higher risk for this cancer.
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Using an air quality monitor to encourage smoke-free homes for cancer patients
This study is testing if using an air quality monitor can help cancer patients who smoke create smoke-free homes and quit smoking.
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Combining Siltuximab with Melphalan for Multiple Myeloma Patients Undergoing Stem Cell Transplant
This study is testing if combining a new drug called siltuximab with a standard treatment for multiple myeloma can help patients feel better after a stem cell transplant.
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Testing Abemaciclib with Radiation Therapy for Metastatic Breast Cancer
This study is testing different doses of the drug abemaciclib in people with metastatic breast cancer who are also getting hormone therapy and radiation to see if it helps them better manage their symptoms.
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3D imaging with Scaniverse to guide head and neck surgery
This study will test whether creating 3D images from standard scans and an ultrasound using the Scaniverse app helps surgeons plan and guide head and neck surgery for adults at MSK.
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Understanding how rectal cancer responds to standard treatment before surgery
This study is testing how well standard treatments for rectal cancer work before surgery to see if they can help predict how the cancer will change.
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Mesothelin-targeted CAR T-cell therapy for esophagogastric cancer
This study is testing a new treatment that uses modified immune cells to target and attack tumors in people with advanced esophagogastric cancer.
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Testing a new combination treatment for advanced melanoma
This study is testing a new combination of three treatments for people with advanced melanoma that hasn't improved with other therapies to see if it can help them feel better.
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Testing sotorasib for advanced non-small cell lung cancer with a KRAS G12C mutation
This study is testing if a new drug called sotorasib can help people with advanced non-small cell lung cancer that has a specific KRAS G12C mutation and who haven't had treatment yet since their cancer got worse.
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Comparing personalized radiation therapy to standard radiation therapy for HPV-positive throat cancer
This study is testing if a personalized radiation treatment with a lower dose can help people with HPV-positive throat cancer feel better and have fewer side effects compared to standard radiation therapy.
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Comparing two treatment combinations for Hairy Cell Leukemia
This study is testing whether a new combination of drugs can work better and cause fewer side effects than the standard treatment for patients with Hairy Cell Leukemia who have a specific genetic mutation.
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Registry for esophageal and gastroesophageal junction cancer
This study collects information from patients with newly diagnosed stage IV esophageal or gastroesophageal junction cancer to see how different treatments affect their quality of life and outcomes.
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Comparing mobile health screening to traditional methods for early detection of oral cancer in rural Varanasi.
This study tests if using mobile health screenings can help find oral cancer earlier than traditional methods for people living in rural Varanasi.
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Using tislelizumab to treat colorectal cancer in Nigeria
This study is testing if a new cancer drug called tislelizumab can help adults in Nigeria with a specific type of colorectal cancer who haven't had treatment before.
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Reduced chemotherapy and antibody treatment for children with high-risk neuroblastoma
This study is testing a new, lighter chemotherapy and antibody treatment for children with high-risk neuroblastoma to see if it helps them get better.
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Testing radiation therapy after surgery for oral tongue cancer
This study is testing if a special type of radiation therapy that avoids the surgery area can help people with oral tongue cancer have fewer side effects and lower chances of the cancer coming back after surgery.
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Treatment with Sacituzumab Govitecan for Mesothelioma
This study tests if a new treatment called sacituzumab govitecan can help people with mesothelioma who have already tried other therapies feel better and manage their disease.
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Combining Tinengotinib with Standard Treatments for Prostate Cancer
This study is testing if adding tinengotinib to standard prostate cancer treatments can help men with advanced prostate cancer feel better and improve their outcomes.
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Emapalumab treatment for pediatric aplastic anemia
This study is testing if a new treatment called emapalumab can help children with severe aplastic anemia do better with their standard treatments.
Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.
Quick answers
How many clinical trials run by Memorial Sloan Kettering Cancer Center are recruiting right now?
311, as of November 12, 2026. 9 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 15 countries. The most sites are in United States (310 trials), Nigeria (3 trials), Netherlands (2 trials), Tanzania (2 trials), Germany (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 107, Phase 1: 41, Phase 1/2: 16, Phase 3: 10. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.