Questionnaires for Adolescents and Young Adults Living with Cancer
Official title: Psychometric and Linguistic Validation of PRO-AYA: Patient-Reported Outcomes for Adolescents and Young Adults (15-39) With Cancer
Run by Memorial Sloan Kettering Cancer Center · NCT07212166 · Data updated 2026-11-12
This project will test whether the PRO-AYA patient-reported outcome questionnaires, including a Spanish version, are clear and useful for adolescents and young adults with cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 15 Years to 39 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Memorial Sloan Kettering Cancer Center Academic / other |
| Locations | 7 sites (Basking Ridge, New Jersey and 6 other locations) |
| Status | Recruiting |
| Started | September 30, 2025 |
| Main results expected | September 30, 2027 |
| Study ends | September 30, 2027 |
| Registry record updated | August 4, 2026 |
| Trial ID | NCT07212166 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are English- or Spanish-proficient individuals aged 15–39 who were diagnosed with cancer or received cancer treatment between ages 15–39 and can complete questionnaires (with assistance if needed), with Cohort 1 also meeting the specified treatment-timing and performance-status criteria.
✕Probably not a fit
People outside the 15–39 age range, those not proficient in English or Spanish, or those unable to complete questionnaires are unlikely to receive direct benefit from this project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project collects survey responses from English- and Spanish-speaking adolescents and young adults (ages 15–39) who were diagnosed with or treated for cancer during that age range. Participants complete the PRO-AYA questionnaires and a subset take part in cognitive interviews to check question clarity and language. The study performs psychometric and linguistic validation of a Spanish PRO-AYA version. Enrollment is conducted through Memorial Sloan Kettering regional sites in New Jersey.
Why it matters
Potential benefit: If validated, these questionnaires could help clinicians and researchers better track symptoms, side effects, and quality of life for adolescents and young adults with cancer.
How similar studies have gone: Other PRO validation studies in cancer populations have often yielded reliable measures, though PRO-AYA's specific focus on adolescents and young adults and its Spanish linguistic validation are more specialized efforts.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * English- or Spanish proficient o As assessed by two items: How well do you speak English? What is your preferred language for healthcare? * Between the ages of 15-39 * Diagnosed with cancer or the recurrence of a cancer as per clinician report and/or received active treatment for cancer between the ages of 15-39 * Able to complete questionnaires by themselves or with assistance as per self-report * For Cohort 1 ONLY: * 3 months from last treatment without plan to initiate any form of cancer-directed treatment in the next 3 months OR * On chronic cancer-directed therapy for the last 3 months without plan to change cancer-directed therapy in the next 3 months AND * ECOG Performance Status (0-4) or KPS/Lansky Score (0-100)
Where it's running
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Memorial Sloan Kettering Basking Ridge (Consent Only)
Basking Ridge, New Jersey, United States Recruiting -
Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey, United States Recruiting -
Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey, United States Recruiting -
Memorial Sloan Kettering Commack (Consent Only)
Commack, New York, United States Recruiting -
Memorial Sloan Kettering Westchester (Consent Only)
Harrison, New York, United States Recruiting -
Memorial Sloan Kettering Cancer Center
New York, New York, United States Recruiting
Show 1 more location
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Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York, United States Recruiting
Study contacts
- Principal investigator: Thomas Atkinson, PhD — Memorial Sloan Kettering Cancer Center
- Study coordinator: Thomas Atkinson, PhD
- Email: atkinsot@mskcc.org
- Phone: 646-888-0089
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.