Registry for people with symptomatic bone metastases
The International Bone Metastasis Registry
This registry collects health information from adults with symptomatic bone metastases who need treatment for painful or unstable bone lesions to learn more about outcomes and care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 22 Years and up |
| Sex | All |
| Sponsor | Memorial Sloan Kettering Cancer Center Academic / other |
| Locations | 7 sites (Basking Ridge, New Jersey and 6 other locations) |
| Trial ID | NCT07391410 on ClinicalTrials.gov |
What this trial studies
This observational registry enrolls adults (age ≥22) with biopsy-proven or clinically apparent symptomatic bone metastases that require an intervention. Participants receive standard clinical treatments—such as radiotherapy, cryotherapy, radiofrequency ablation, operative fixation, prosthetic replacement, or amputation—while the registry collects standardized data on symptoms, treatments, complications, and follow-up. Data are entered into a central database to capture real-world patterns of care and patient outcomes across participating centers. No experimental therapies are assigned; the dataset is intended to support future research and quality-improvement efforts.
Who should consider this trial
Good fit: Adults aged 22 or older with biopsy-proven or clinically evident symptomatic bone metastases that require an intervention are the ideal candidates for this registry.
Not a fit: People under 22 years old, those without symptomatic lesions or not requiring intervention, and patients unable to attend participating centers are unlikely to benefit from joining this registry.
Why it matters
Potential benefit: If successful, the registry could help clinicians identify which interventions most effectively control symptoms and reduce complications for people with bone metastases.
How similar studies have performed: Other observational registries and real-world datasets for bone metastases have provided useful insights into treatment patterns and outcomes, so this approach is established and informative rather than novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥22 years * Biopsy-proven or clinically obvious metastatic bone disease * Symptomatic bone lesion requiring intervention * This includes but is not limited to radiotherapy, cryotherapy, radiofrequency ablation, operative fixation, prosthetic replacement, amputation, or any combination of the above Exclusion Criteria: * Age \<22 years
Where this trial is running
Basking Ridge, New Jersey and 6 other locations
- Memorial Sloan Kettering Basking Ridge (All Protocol Activities) — Basking Ridge, New Jersey, United States (Recruiting)
- Memorial Sloan Kettering Monmouth (All Protocol Activities) — Middletown, New Jersey, United States (Recruiting)
- Memorial Sloan Kettering Bergen (All Protocol Activities) — Montvale, New Jersey, United States (Recruiting)
- Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities) — Commack, New York, United States (Recruiting)
- Memorial Sloan Kettering Westchester (All Protocol Activities) — Harrison, New York, United States (Recruiting)
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York, New York, United States (Recruiting)
- Memorial Sloan Kettering Nassau (All Protocol Activities) — Uniondale, New York, United States (Recruiting)
Study contacts
- Principal investigator: Jonathan Forsberg, MD, PhD — Memorial Sloan Kettering Cancer Center
- Study coordinator: Jonathan Forsberg, MD, PhD
- Email: forsbej@mskcc.org
- Phone: 212-639-2076
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.