Clinical trial Recruiting at 7 sites Observational Ages 22 and up

Registry for people with symptomatic bone metastases

Official title: The International Bone Metastasis Registry

Run by Memorial Sloan Kettering Cancer Center · NCT07391410 · Data updated 2026-11-12

This registry collects health information from adults with symptomatic bone metastases who need treatment for painful or unstable bone lesions to learn more about outcomes and care.

Quick facts

Study typeObservational
Ages22 Years and up
SexAll
Enrollment500 (estimated)
SponsorMemorial Sloan Kettering Cancer Center
Academic / other
Locations7 sites (Basking Ridge, New Jersey and 6 other locations)
StatusRecruiting
StartedJanuary 13, 2026
Main results expectedJanuary 2031
Study endsJanuary 2031
Registry record updatedAugust 20, 2026
Trial IDNCT07391410 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 22 or older with biopsy-proven or clinically evident symptomatic bone metastases that require an intervention are the ideal candidates for this registry.

Probably not a fit

People under 22 years old, those without symptomatic lesions or not requiring intervention, and patients unable to attend participating centers are unlikely to benefit from joining this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry enrolls adults (age ≥22) with biopsy-proven or clinically apparent symptomatic bone metastases that require an intervention. Participants receive standard clinical treatments—such as radiotherapy, cryotherapy, radiofrequency ablation, operative fixation, prosthetic replacement, or amputation—while the registry collects standardized data on symptoms, treatments, complications, and follow-up. Data are entered into a central database to capture real-world patterns of care and patient outcomes across participating centers. No experimental therapies are assigned; the dataset is intended to support future research and quality-improvement efforts.

Why it matters

Potential benefit: If successful, the registry could help clinicians identify which interventions most effectively control symptoms and reduce complications for people with bone metastases.

How similar studies have gone: Other observational registries and real-world datasets for bone metastases have provided useful insights into treatment patterns and outcomes, so this approach is established and informative rather than novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥22 years
* Biopsy-proven or clinically obvious metastatic bone disease . For purposes of this study, metastatic bone disease includes skeletal involvement from multiple myeloma.
* Symptomatic bone lesion requiring intervention
* This includes but is not limited to radiotherapy, cryotherapy, radiofrequency ablation, operative fixation, prosthetic replacement, amputation, or any combination of the above

Exclusion Criteria:

* Age \<22 years

Where it's running

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
    Basking Ridge, New Jersey, United States
    Recruiting
  • Memorial Sloan Kettering Monmouth (All Protocol Activities)
    Middletown, New Jersey, United States
    Recruiting
  • Memorial Sloan Kettering Bergen (All Protocol Activities)
    Montvale, New Jersey, United States
    Recruiting
  • Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities)
    Commack, New York, United States
    Recruiting
  • Memorial Sloan Kettering Westchester (All Protocol Activities)
    Harrison, New York, United States
    Recruiting
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)
    New York, New York, United States
    Recruiting
Show 1 more location
  • Memorial Sloan Kettering Nassau (All Protocol Activities)
    Uniondale, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Jonathan Forsberg, MD, PhD — Memorial Sloan Kettering Cancer Center
  • Study coordinator: Jonathan Forsberg, MD, PhD
  • Email: forsbej@mskcc.org
  • Phone: 212-639-2076

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.