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Comparing two OCT scanners for people with ocular tumors

Ocular Imaging for Monitoring of Ocular Tumor Disease

Not applicable Interventional Memorial Sloan Kettering Cancer Center · NCT07449195

This will try two different OCT imaging devices to see which makes clearer eye images for adults with ocular tumors.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorMemorial Sloan Kettering Cancer Center Academic / other
Locations7 sites (Basking Ridge, New Jersey and 6 other locations)
Trial IDNCT07449195 on ClinicalTrials.gov

What this trial studies

This interventional comparison obtains images of eyes with intraocular or ocular surface tumors using the Intalight Dream and the Heidelberg Spectralis OCT devices. Eligible eyes are dilated and imaged on both machines during clinic visits, and resulting scans are compared for image clarity, tumor detail, and ability to visualize the retina or lesion. The procedure is noninvasive and brief, requiring the patient to fixate and sit still for short periods. Findings will show whether one device provides more useful imaging for diagnosing or monitoring ocular tumors.

Who should consider this trial

Good fit: Adults (≥18 years) with at least one intraocular or ocular surface tumor who have a natural or intraocular lens, pupils that dilate to about 3 mm, clear media for retinal imaging, and the ability to fixate and sit still.

Not a fit: Patients with opaque lenses or other eye disease that prevents viewing the retina, pupils that cannot dilate to the required size, or those unable to fixate or remain still are unlikely to benefit from the imaging comparison.

Why it matters

Potential benefit: If one device yields consistently clearer tumor images, clinicians could detect and follow ocular tumors more accurately without extra invasive testing.

How similar studies have performed: OCT is widely used and prior work shows it can image eye tumors and that device-to-device comparisons are informative, though direct comparisons focused specifically on ocular tumors are less common.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Age ≥18 years.
* At least 1 eye that has an intraocular or ocular surface tumor.
* The presence of a natural crystalline lens or intraocular lens.
* Pupils that can dilate up to at least 3 mm in the study eyes.
* The absence of opaque natural crystalline lenses or the presence of any ocular disease that prevents the view of the retina for imaging.
* Patients must be able to fixate on the imaging target.
* Patients must be able to sit still for a period of time (approximately 2 minutes).

Exclusion Criteria:

* Does not meet ALL of the above conditions

Where this trial is running

Basking Ridge, New Jersey and 6 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Ocular TumorOcular Tumors25-314Memorial Sloan Kettering Cancer Center
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.