Clinical trial Recruiting at 2 sites Interventional Ages 18 and up

Acupuncture for joint pain in breast cancer survivors on hormonal therapy

Official title: Researching the Implementation of Acupuncture for Chronic Musculoskeletal Pain in Diverse Underserved Cancer Survivors (ReIMAGINE)

Run by Memorial Sloan Kettering Cancer Center · NCT06814977 · Data updated 2026-11-12

This study is testing if acupuncture can help reduce joint pain in breast cancer survivors from Black, Asian, and Hispanic backgrounds who are on hormonal therapy.

More Cancer Survivor trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorMemorial Sloan Kettering Cancer Center
Academic / other
Drugs / interventionschemotherapy, radiation
Locations2 sites (New York, New York and 1 other locations)
StatusRecruiting
StartedJanuary 31, 2025
Main results expectedJune 30, 2028
Study endsJune 30, 2028
Registry record updatedOctober 15, 2026
Trial IDNCT06814977 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are English- or Spanish-speaking Black, Asian, or Hispanic women with a history of stage I, II, or III breast cancer experiencing significant joint pain due to hormonal therapy.

Probably not a fit

Patients with active oncological disease or those who have recently undergone chemotherapy, surgery, or radiation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the feasibility of acupuncture as a treatment for joint pain experienced by breast cancer survivors who are undergoing hormonal therapies. It focuses on women of Black, Asian, and Hispanic descent with a history of stage I, II, or III breast cancer, who have been experiencing significant pain attributed to their treatment. Participants will receive acupuncture and complete questionnaires to assess their pain levels and overall well-being. The study aims to determine if acupuncture can effectively alleviate joint pain in this specific patient population.

Why it matters

Potential benefit: If successful, this study could provide a non-pharmacological option for managing joint pain in breast cancer survivors undergoing hormonal therapy.

How similar studies have gone: Previous studies have shown promising results for acupuncture in managing pain, but this specific approach for breast cancer survivors on hormonal therapy is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English- or Spanish-speaking adults
* Non white or Hispanic women with a prior cancer diagnosis
* Stable oncological disease or no evidence oncological of disease per clinical documentation or clinician assessment
* Worst pain rated ≥4 on a 0-10 scale in the preceding week
* ≥15 days with pain in the past 30 days
* Pain lasting ≥1 month
* Willing and able to complete questionnaires and other study activities
* Willing and able to provide informed consent for the trial

Exclusion Criteria:

* Completed active treatment (chemotherapy, surgery, radiation, transplantation) \<4 weeks prior to study
* Maintenance therapies are allowed
* Pain attributed to inflammatory arthritis (e.g., rheumatoid arthritis, gout)
* Other non-musculoskeletal pain syndromes (eg, headache, visceral abdominal pain, neuropathic pain) can be present as comorbid conditions if the patient reports musculoskeletal pain as the primary source of pain
* Procedures involving affected joints within the last month or planned in the next 14 weeks
* Acupuncture use for pain in the past three months
* Implanted electronic device (e.g., pacemaker)

Where it's running

  • Memorial Sloan Kettering Cancer Center (All protocol activites)
    New York, New York, United States
    Recruiting
  • Jamaica Hospital Medical Center
    Richmond Hill, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Kevin Liou, MD — Memorial Sloan Kettering Cancer Center
  • Study coordinator: Kevin Liou, MD
  • Email: liouk@mskcc.org
  • Phone: 646-608-8563

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.