Comparing mobile health screening to traditional methods for early detection of oral cancer in rural Varanasi.
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
This study tests if using mobile health screenings can help find oral cancer earlier than traditional methods for people living in rural Varanasi.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5122 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Memorial Sloan Kettering Cancer Center Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT06535867 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of mobile health (mHealth) screening compared to conventional screening methods for the early detection of oral potentially malignant disorders and oral cancer among the rural population of Varanasi. It aims to enhance awareness of oral cancer and improve the diagnostic knowledge of frontline health providers. The study includes long-term surveillance to help downstage oral cancer in India, focusing on individuals with specific risk factors and symptoms. Participants will be monitored for signs of oral cancer and pre-cancerous lesions.
Who should consider this trial
Good fit: Ideal candidates include individuals over 18 with habits such as smoking or chewing betel leaf, or those over 40 regardless of habits.
Not a fit: Patients already diagnosed with oral cancer or undergoing treatment for it will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to earlier detection of oral cancer, improving patient outcomes and survival rates.
How similar studies have performed: Other studies have shown promise in using mobile health technologies for cancer screening, suggesting a potential for success in this novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Positive for any one or more of the following: * All individuals aged above 18 years positive for habits (smoking and smokeless tobacco, chewing betel leaf, areca nut, paan masala, and/or regular use of alcohol) * Clinical signs/symptoms (non-healing ulcers, white/ red/red \& white patches in the mouth, restriction of mouth opening and swelling of the neck) * All individuals aged above 40 irrespective of habit/oral lesions Exclusion Criteria: * Individuals already diagnosed with oral cancer and undergoing treatment for oral cancer * Under treatment for tuberculosis or suffering from any acute illness/ debilitating systemic disorders
Where this trial is running
New York, New York
- Memorial Sloan Kettering Cancer Center (All protocol activites) — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Milind Rajadhyaksha, PhD — Memorial Sloan Kettering Cancer Center
- Study coordinator: Milind Rajadhyaksha, PhD
- Email: rajadhym@mskcc.org
- Phone: 646-608-2364
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.