Sponsor or institution
Clinical trials and research at H. Lee Moffitt Cancer Ctr & Res Inst
As of November 12, 2026, Find a Trial lists 259 NIH-funded research projects at this institution, with $125.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 259NIH research projects
NIH-funded research (newest 40 of 259)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Central Laboratory Core for Advanced Cancer Research
A central laboratory core provides shared, specialized services to cancer researchers to help advance patient-focused studies.
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Novel idea: Epstein-Barr virus and eye cancer in people living with HIV in Zimbabwe
A study explores whether Epstein-Barr virus could cause a type of eye cancer in people living with HIV in Zimbabwe.
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Administration & Coordinating Core
This grant funds a central hub to help coordinate cancer research efforts at a major cancer center so researchers can work together more efficiently.
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Developmental and Career Enhancement Core (for researchers)
A dedicated program to help researchers build skills and advance their careers over several years.
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Central Laboratory Core for Cancer Research
A cancer research center is funding a shared lab core to support various studies over the next five years.
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Exploring how HPV-related cancers affect people living with HIV and what helps survival
A patient-friendly look at a project studying how HPV-related cancers and HIV interact and what factors influence survival.
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Administration and Coordination Core for a Cancer Center
This grant funds a centralized team to organize and support cancer research activities at a major cancer center to help patients access better care and new treatments sooner.
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Developmental & Career Enhancement Core
This grant provides support to help researchers grow professionally and build capabilities at Moffitt Cancer Center for five years.
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Oral HPV Research in Latin Americans Living with HIV
A study to understand how HPV-related oropharyngeal cancer develops in people living with HIV and what factors and biomarkers could help prevent or detect it early.
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Oral HPV Research in Latin Americans Living with HIV
A study to understand how HPV-related oropharyngeal cancer develops in people living with HIV and to find ways to identify and prevent it.
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AI-assisted standardization of data elements and metrics across studies
A U01 grant explores using artificial intelligence to turn data from research studies into common, shareable building blocks so future studies can reuse and compare data more easily.
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Ending Tobacco Use with a Smartphone Program for Cambodian People Living with HIV/AIDS
A smartphone-based quit-smoking program designed for people living with HIV/AIDS in Cambodia to help reduce tobacco use alongside HIV treatment.
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Partnership to Understand Virus-and-Immune Factors in HIV-Associated Cancers
A multi-site project will study how viruses, the immune system, and cancer interact in people living with HIV to improve prevention, detection, and treatment of AIDS-related cancers.
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Partnership to Understand Virus-Driven Cancer in People Living with HIV
A collaborative effort to study how viruses, the immune system, and cancer interact in people living with HIV to improve prevention and treatment of virus-related cancers.
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Oral bacteria and brain metastasis: how the mouth may influence brain tumors
A study exploring how oral microbes may affect brain metastases and patient outcomes, with potential to guide new microbiome-based approaches.
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Notch signaling control tools to tailor cell signaling
A patient-focused window into how researchers are creating safe, targeted ways to turn Notch signaling on or off in specific tissues to help stem cell and immune-related conditions.
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Targeting harmful brain-leptomeningeal cancer environment by reducing branched-chain keto acids
Aims to see if lowering branched-chain keto acids in the brain’s fluid can slow melanoma spread to the brain covering and help immune cells fight the cancer.
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Selenium Metabolism and Selenoprotein Formation and Its Link to Alzheimer’s Disease
Researchers are studying how selenium is processed in the body and how selenoproteins are made, to understand potential connections to Alzheimer’s disease and dementia.
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Oral HPV Research in Latin Americans Living with HIV
This study looks at how HPV-related oropharyngeal cancer risk can be understood and reduced among people living with HIV in Latin America.
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Developmental & Career Enhancement Core for HIV-related cancers
This grant helps build the careers of junior scientists in the U.S. and southern Africa to study infections and HIV-related cancers.
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Central Laboratory Core supports biobanking and viral/immunologic testing for HIV-related cancer research
A Central Laboratory Core helps collect and process biospecimens from people living with HIV to study viruses, immune responses, and cancer-related factors.
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Data Management & Statistics Core for Cancer Research in People Living with HIV in Africa
A dedicated statistics and data management core supports cancer research in people living with HIV in sub-Saharan Africa.
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Novel look at EBV as a possible cause of eye cancer in people with HIV in Zimbabwe
A study will explore whether Epstein-Barr virus may contribute to an eye cancer (cSCC) in people living with HIV in Zimbabwe.
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HPV-related cancers in people living with HIV: understanding tumor and immune factors
This grant studies why people with HIV have higher HPV-related cancer rates and worse outcomes, by looking at how tumors and the immune system interact and how therapies might help in low- and middle-income countries.
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Administrative & Coordinating Core for a HIV-associated cancer research partnership
A national cancer center-led program is coordinating research efforts to understand viral and immune factors in cancers affecting people living with HIV.
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Partnership to Understand Viral and Immune Factors in HIV-Related Cancers
A collaboration of HIV, virus-related cancer, and immune researchers will study virus-driven cancers that affect people living with HIV to improve prevention, detection, and treatment.
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Ecological Core for Tumor Microenvironment Modeling
A cancer research grant supporting computational and imaging work to understand how tumors interact with their surrounding tissue over time, with a focus on non-small cell lung cancer.
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Mathematical Modeling Core for Cancer Tumor Ecology
A mathematical modeling core helps researchers understand how tumors grow and respond to treatment by linking data from cells, tissues, and patients.
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Outreach Core for cancer systems biology training
A one-week interdisciplinary workshop to train the next generation of cancer systems biologists by blending biology, math, and patient perspectives.
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Understanding how cancer-supportive tissue affects resistance to ALK and KRAS therapies
A research team will study how the tumor’s surrounding tissue changes as cancer cells become resistant to ALK and KRAS-targeted treatments, aiming to find better combination strategies for long-lasting remission.
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Delta immune ecology of NSCLC in KRAS-mutant cancers
A study in people with NSCLC (especially KRAS-mutant) will examine how immune cells and tumor interactions change during treatment and how this could guide better therapies.
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Understanding how lung cancer and its surroundings change during treatment
A research effort to map how non-small cell lung cancer evolves and how its lung environment changes during therapy to find ways to overcome treatment resistance.
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Quantitative Imaging Center to Improve Early Cancer Detection
A national center at Moffitt Cancer Center is testing advanced imaging biomarkers and AI tools to improve early cancer detection and reduce false positives.
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Cancer data science platform to help researchers analyze cancer data
A nationwide cancer data platform is being built to make it easier for doctors and scientists to connect datasets, run analyses, and use cloud resources, so cancer research can move faster and benefit patients.
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Does Epstein-Barr virus cause conjunctival (eye) cancer in people with HIV in Zimbabwe?
This project looks for a link between the Epstein-Barr virus and conjunctival squamous cell carcinoma in people living with HIV in Zimbabwe.
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HPV-related cancers in people living with HIV and factors that affect survival
This project looks at how HPV and immune system changes affect HPV-related cancers in people living with HIV to help improve prevention and treatment.
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Central lab for virus and cancer testing in people living with HIV
This project collects and stores blood and tissue samples and runs virus and immune tests to help researchers learn more about cancer in people living with HIV.
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HPV-related cancers in people living with HIV — viral and immune factors tied to survival
Researchers are looking at how HPV and immune system differences in people living with HIV affect outcomes from HPV-related cancers.
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Disrupting the Prostate Cancer Environment in African American Men to Help Immunotherapy Work Better
A cancer research project aims to understand why prostate cancer behaves differently in African American men and how immune therapies might work better for them.
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Ending Tobacco Use with a smartphone program for Cambodians living with HIV
A smartphone-based, tailored smoking-cessation program for people living with HIV in Cambodia is being tested to help them quit smoking.
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