Quantitative Imaging Center to Improve Early Cancer Detection
Official title: Quantitative Imaging Clinical Validation Center at Moffitt Cancer Center
Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11415803 · Data updated 2026-11-12
A national center at Moffitt Cancer Center is testing advanced imaging biomarkers and AI tools to improve early cancer detection and reduce false positives.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | July 22, 2016 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,322,710 |
| NIH project number | 5U01CA200464-09 |
| Project ID | NIH-11415803 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients undergoing cancer screening or diagnostic imaging who are at risk for breast or lung cancer and whose imaging results could benefit from improved biomarker-based interpretation.
✕Less likely to help
Patients not undergoing cancer screening or whose imaging findings are already definitive may not benefit.
What this research studies
This grant supports a center that develops and validates image-based biomarkers from medical scans to improve early cancer detection. It builds on prior work to validate AI-driven biomarkers for breast and lung cancer, aiming to reduce unnecessary biopsies and overtreatment. The project will use real patient imaging data to refine quantitative imaging methods and create a repository of biomarker data to support future clinical use. The goal is to provide reliable imaging signals that help clinicians decide which patients need further testing or treatment.
Why it matters
Potential benefit: If successful, patients could receive more accurate screening results, fewer unnecessary procedures, and earlier, more precise interventions for cancer.
How similar studies have gone: Previous validation efforts have demonstrated the potential of image biomarkers to improve cancer risk stratification and diagnostic decisions.
Where this research is happening
-
H. Lee Moffitt Cancer Ctr & Res Inst
Tampa, United States Active
Researchers
- Principal investigator: Heine, John J — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Heine, John J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.