Exploring how HPV-related cancers affect people living with HIV and what helps survival
Official title: Project 1: Exploring viral and immunological factors of HPV associated cancers in PLWH and its relation to survival
Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11625524 · Data updated 2026-11-12
A patient-friendly look at a project studying how HPV-related cancers and HIV interact and what factors influence survival.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | August 3, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $89,319 |
| NIH project number | 3U54CA277834-04S1 |
| Project ID | NIH-11625524 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients living with HIV who have or are at risk for HPV-related cancers.
✕Less likely to help
People without HIV or without HPV-related cancers may not directly benefit from this study.
What this research studies
This grant funds a large, team-based effort to understand the viral and immune factors driving HPV-associated cancers in people living with HIV, with the goal of improving outcomes. Researchers will examine biological samples and patient data to identify clues about why some patients do better than others. The work will involve collaborating across cancer and infectious disease specialists to translate findings into ideas for better prevention, screening, and treatment approaches. If you have HPV-related cancer and live with HIV, your experiences and samples could help advance this work.
Why it matters
Potential benefit: Insights from this research could lead to improved survival and personalized care for patients with HPV-related cancers who are also living with HIV.
How similar studies have gone: Related research has shown that immune and viral factors influence cancer behavior, but this project aims to deepen understanding in the HIV-positive population.
Where this research is happening
-
H. Lee Moffitt Cancer Ctr & Res Inst
Tampa, United States Active
Researchers
- Principal investigator: Botha, Matthys Hendrik — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Botha, Matthys Hendrik
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.