Central Laboratory Core supports biobanking and viral/immunologic testing for HIV-related cancer research
Official title: Central Laboratory Core
Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11418505 · Data updated 2026-11-12
A Central Laboratory Core helps collect and process biospecimens from people living with HIV to study viruses, immune responses, and cancer-related factors.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | August 3, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $92,407 |
| NIH project number | 5U54CA277834-04 |
| Project ID | NIH-11418505 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV who may develop or have cancer, and who can contribute biospecimens for centralized testing.
✕Less likely to help
Patients whose samples are not available for analysis or whose clinical context does not align with the translational aims may see limited direct benefit.
What this research studies
This grant funds a centralized lab core that provides biobanking and standardized virologic and immunologic analyses for well-annotated biospecimens. It supports translational studies and future pilot projects within the PAVILION program aimed at understanding how viral and immune landscapes intersect with oncology in people living with HIV, including international LMIC collaborations. The Core is co-led by international experts and leverages established laboratories to ensure robust, high-quality pathology evaluation and endpoint adjudication. The work is designed to inform prevention and cancer treatment strategies to reduce cancer burden in PLWH in resource-limited settings. Overall, it lays the infrastructure for rigorous analyses that could guide future clinical research and interventions.
Why it matters
Potential benefit: If successful, this core could accelerate understanding of how HIV-related factors influence cancer and improve prevention and treatment options for people living with HIV who develop cancer.
How similar studies have gone: Previous projects with centralized biobanking and standardized testing have improved data quality and comparability across sites, supporting translational cancer research in HIV.
Where this research is happening
-
H. Lee Moffitt Cancer Ctr & Res Inst
Tampa, United States Active
Researchers
- Principal investigator: Dhillon, Jasreman — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Dhillon, Jasreman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.