Partnership to Understand Virus-Driven Cancer in People Living with HIV
Official title: Partnership to Assess Viral and Immune Landscape Intersections with ONcology for People Living with HIV (PAVILION)
Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11535247 · Data updated 2026-11-12
A collaborative effort to study how viruses, the immune system, and cancer interact in people living with HIV to improve prevention and treatment of virus-related cancers.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | August 3, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $224,572 |
| NIH project number | 3U54CA277834-04S1 |
| Project ID | NIH-11535247 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV who are at risk for or have virus-associated cancers, including HPV-related cancers and other virus-driven malignancies.
✕Less likely to help
Individuals without HIV or without a virus-associated cancer may not directly benefit from this project.
What this research studies
PAVILION brings together HIV, HPV, EBV, and cancer researchers at experienced sites to study virus-associated tumors that affect people living with HIV. The program focuses on understanding how viral, immune, and clinical factors drive cancer in this population, with an emphasis on cancers that are not well understood. Results aim to inform better prevention, early detection, and treatment strategies for PLWH who are at higher risk for virus-related malignancies. The work will leverage existing HIV and cancer research networks to accelerate discoveries relevant to US patients.
Why it matters
Potential benefit: If successful, the project could lead to earlier cancer detection and more effective, tailored treatments for PLWH facing virus-associated cancers.
How similar studies have gone: Previous efforts have shown that understanding viral and immune interactions can inform cancer prevention and treatment, but much remains unknown in PLWH.
Where this research is happening
-
H. Lee Moffitt Cancer Ctr & Res Inst
Tampa, United States Active
Researchers
- Principal investigator: Giuliano, Anna R. — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Giuliano, Anna R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.