Mathematical Modeling Core for Cancer Tumor Ecology
Official title: Core 1: Mathematical Core
Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-11416448 · Data updated 2026-11-12
A mathematical modeling core helps researchers understand how tumors grow and respond to treatment by linking data from cells, tissues, and patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | September 15, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $240,378 |
| NIH project number | 5U54CA274507-04 |
| Project ID | NIH-11416448 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients whose tumors are studied in clinical projects or who contribute data to model calibration.
✕Less likely to help
Patients whose data are not used for model development or who are not part of linked clinical studies.
What this research studies
This core creates computer models that mimic how cancer ecosystems change over time, from early development to therapy. It uses spatial agent-based models to represent many cell types and molecules and integrates patient data when available. The goal is to bridge gaps between lab experiments and real-world patient outcomes. Researchers can test ideas in silico to see which mechanisms might drive tumor progression or response to treatment. The platform is designed to be fast and adaptable to support related cancer research projects.
Why it matters
Potential benefit: If successful, this core could improve our understanding of tumor behavior and help tailor therapies based on patient-specific tumor dynamics.
How similar studies have gone: Other cancer modeling efforts have shown that well-constructed mathematical models can align with clinical trends and predict responses to therapy.
Where this research is happening
-
H. Lee Moffitt Cancer Ctr & Res Inst
Tampa, United States Active
Researchers
- Principal investigator: Anderson, Alexander Robertson Allan — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Anderson, Alexander Robertson Allan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.