Sponsor or institution
Clinical trials and research at Feinstein Institute for Medical Research
As of November 12, 2026, Find a Trial lists 163 NIH-funded research projects at this institution, with $105.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 163NIH research projects
NIH-funded research (newest 40 of 163)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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MAIA: How methamphetamine affects immune cells in people with HIV
A study to understand how meth use changes the immune system and HIV biology in people living with HIV who are on standard therapy.
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Phthalate Exposure and How It Affects Newborns in the NICU
This grant looks at how chemicals called phthalates in the NICU environment may affect the health and development of newborns, especially those born prematurely.
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How IL-10 and TGF-ß help HIV hide in Tfh cells in lymph nodes
This project looks at how specific immune signals in lymph nodes may help HIV persist in certain T cells even when ART is working.
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Northwell Health NCORP brings cancer research to the community
This grant supports a community cancer research program that makes national cancer studies available to patients in our area.
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Understanding ANA+ and ANA- B cells in people with SLE and healthy individuals
Researchers will study how different B cell types behave in lupus patients compared with healthy people to identify clues for better treatments.
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Predicting lupus flares by analyzing blood and urine
A patient-friendly look at a program aiming to better predict lupus flares from blood and urine clues to help people stay in remission.
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Autoimmune Disease Center focus on lupus and immune cell targets
A national program aims to better understand how immune cells drive lupus so doctors can tailor treatments and identify when patients are likely to flare.
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Learning from remission and relapse in lupus (SLE)
Researchers are studying people with systemic lupus erythematosus who are in long-term remission without steroids or immunosuppressants to understand their immune cells, brain function, and what might predict relapse.
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Learning from Remission and Relapse in SLE
A program to study people with systemic lupus erythematosus who are in long-term remission to understand immune and brain signals that might predict relapse.
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Kids’ Night-Time Blood Pressure and Kidney Disease in Glomerulopathy
A study in children with proteinuric glomerulopathies will look at nighttime blood pressure, heart and kidney health, and related molecular markers to understand how these factors relate to future cardiovascular risk.
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Understanding radiation’s impact on immune cells and how to counter it
This NIH grant looks at how radiation hurts the body’s first responders to infection and tests ways to fix it, with potential benefits for people exposed to high radiation like after accidents or disasters.
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Understanding how stimulating the trigeminal nerve could help mood and thinking in dementia
A noninvasive brain-stimulation approach aims to boost serotonin signaling to ease mood and cognitive symptoms in people with dementia.
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Defining chronic endometritis with new tissue and blood tests to improve diagnosis
Researchers will explore advanced tissue and blood-based methods to better diagnose chronic endometritis in people with unexplained infertility.
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Reducing Burden for Care Partners of People with Alzheimer’s and Related Dementias
This project tests a user-friendly Web tool to help care partners of people with dementia manage oropharyngeal dysphagia and reduce daily caregiving burden.
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Understanding how the brain shapes breathing to help people with persistent breathlessness
Researchers are studying how higher brain regions influence breathing and the feeling of breathlessness in people with conditions like COPD and asthma, with the goal of safer, non-ventilation-impairing treatments.
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Hidden brain changes in people with lupus who are in remission
This project uses brain scans, blood tests, and thinking tests to look for hidden brain problems in people whose lupus is currently quiet.
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Single-cell profiling of immune cells in people with lupus in remission
This project looks at blood immune cells and autoantibodies in people with lupus who are in long-term remission to find patterns that may predict who later relapses.
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Lupus data integration and analysis support
Tools and analyses to help researchers combine clinical and molecular data to better understand and treat people with lupus.
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Why lupus stays quiet for some people and flares for others
Looking at immune cells and brain function in people with lupus who are in long-term remission without steroids or immunosuppressants to find markers linked to future relapse.
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Heat and neighborhood stressors worsen stroke outcomes in people with Alzheimer’s and related dementias
In people with Alzheimer’s disease or related dementias, this project studies how hot weather and neighborhood-level socioeconomic stress affect stroke outcomes.
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Understanding how B cells and macrophages drive lupus activity
A U19 grant aims to uncover how immune cells like B cells and macrophages influence lupus flares so future treatments can keep people with SLE in remission.
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Biomarkers to Guide Early Clozapine Use in First-Episode Psychosis
This grant tests whether brain scans and a simple genetic test can help doctors decide earlier if a patient with a first-episode psychosis should switch to Clozapine to improve outcomes.
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How the body’s immune system goes off-track during deadly infections
Scientists are studying why the body's early immune response sometimes spirals into dangerous inflammation during severe infections, with a focus on molecules that may drive harm.
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Web program to help caregivers safely feed loved ones with dementia who have trouble swallowing
A web-based program to teach family caregivers how to manage swallowing problems and reduce the stress of feeding a loved one with Alzheimer’s or related dementia.
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Comparison of how the body normally counters infection vs. when it overreacts (sepsis)
A clinician-scientist will explore why some patients’ bodies fight infection in a normal balanced way while others develop sepsis, aiming to better tailor treatments in the future.
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Brain networks that control inflammation
A research project explores how specific brain networks control inflammation through signaling between the brain and body, with potential implications for inflammatory conditions.
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How viral infections and ancient virus-like DNA may drive lymphoma in people with HIV
This work looks at whether HIV, Epstein–Barr virus (EBV), and ancient virus-like sequences in our DNA act together to promote a type of lymphoma seen in people with HIV.
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MOMs Program: Integrated Maternal Care to Reduce Severe Maternal Morbidity
A program tested at delivery and early pregnancy to help high-risk Black and Hispanic patients get timely, appropriate care to reduce serious pregnancy complications.
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Role of Beta Spectrin and SMAD in Alcohol-Related Liver Injury
A study to understand how a protein pathway involving betaII-spectrin and SMAD affects liver damage from alcohol and fat-related disease, with potential implications for preventing liver disease.
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Vital signs for psychosis: personalized, always-on markers from speech and language
A patient-friendly approach to using speech and language cues to measure psychosis severity over time, so clinicians can tailor care.
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Predicting Psychosis Outcomes from Electronic Health Records
This project uses machine learning on routine health records to predict long-term outcomes for people with psychosis and tailor their care.
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Understanding how symptoms, thinking skills, daily functioning, and stress interact to predict psychosis in at-risk youth
A new NIH grant will map how clinical symptoms, thinking abilities, everyday functioning, and stressful events combine to influence the chance of developing psychosis in young people at high risk.
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MSP68: a new peptide to help GI damage after high radiation
A new peptide-based medicine (MSP68) is being developed to help people who suffer severe gut damage after large radiation exposure.
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Environmental factors in fetal life and childhood growth trajectory study
A long-term study follows pregnant people and their children to understand how in-utero chemical and psychosocial exposures influence child growth and obesity risk up to age 5.
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Predicting rehospitalization and disengagement in psychosis using automated speech and language analysis
A research project uses voice and language patterns to forecast which people with psychosis in coordinated specialty care might be readmitted to hospital or stop continuing treatment.
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Enhancing Patient Engagement in Learning Health Systems for First Episode Psychosis
A large, multi-site project uses patient and clinician data to understand why people with first episode psychosis drop out of care and how to keep them engaged in treatment.
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Early-Phase Psychosis Care: Improving Treatment Outcomes Through Practice-Based Research
A patient-focused program to improve first-episode psychosis care by learning from real-world clinics and sharing better ways to treat and support people.
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Early-Phase Psychosis: Practice-Based Research to Improve Treatment Outcomes
A coordinated effort to improve care for people experiencing first-episode psychosis by using learning-health-system tools and real-world clinics.
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How radiation affects immune cells and how to protect against infection after exposure
Researchers are studying how radiation changes the body's first responders to infection and how to counteract that damage to help people survive and fight bacteria after radiation exposure.
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Novel ways to keep organs functioning in sepsis
A cancer-style grant is helping scientists understand how to prevent organ failure in people with sepsis by studying immune cells and their signals.
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