Predicting lupus flares by analyzing blood and urine
Official title: Collaborative Project-Predicting LN flare and activity by an analysis of blood and urine
Funded at Feinstein Institute for Medical Research · NIH-11520865 · Data updated 2026-11-12
A patient-friendly look at a program aiming to better predict lupus flares from blood and urine clues to help people stay in remission.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project start | May 1, 2019 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $251,250 |
| NIH project number | 5U19AI144306-08 |
| Project ID | NIH-11520865 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with systemic lupus erythematosus (SLE) who may contribute samples or be considered for flare-prediction strategies through future trials.
✕Less likely to help
People without lupus or those not involved in biomarker-based studies may not directly benefit.
What this research studies
This grant focuses on systemic lupus erythematosus (SLE) and uses blood and urine analyses to understand what happens before a lupus flare. By examining immune system signals, especially B cells and myeloid cells, researchers hope to identify patterns that predict flares and inform which patients should receive specific therapies. The project seeks to translate immune insights into ways to keep lupus under control and guide future clinical trials. It involves collaboration within an Autoimmunity Center of Excellence to study disease states that precede active disease. Participation would help advance personalized approaches to prevent flares and reduce treatment-related side effects.
Why it matters
Potential benefit: If successful, this work could lead to better prediction of lupus flares and more targeted, effective treatments.
How similar studies have gone: Prior work shows that immune markers can precede SLE flares, supporting potential benefits from this approach.
Where this research is happening
-
Feinstein Institute for Medical Research
Manhasset, United States Active
Researchers
- Principal investigator: Davidson, Anne — Feinstein Institute for Medical Research
- Study coordinator: Davidson, Anne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.