Lupus data integration and analysis support
Official title: Core C: Biostatistics and Data Integration Core (BDI Core)
Funded at Feinstein Institute for Medical Research · NIH-11406912 · Data updated 2026-11-12
Tools and analyses to help researchers combine clinical and molecular data to better understand and treat people with lupus.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project start | May 9, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $401,675 |
| NIH project number | 5P01AI172523-03 |
| Project ID | NIH-11406912 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are people with systemic lupus erythematosus (SLE) who can contribute clinical data, blood, or tissue samples to participating research projects.
✕Less likely to help
People without lupus, or lupus patients who are not enrolled at the participating sites or who do not consent to provide samples, would not be directly involved or likely to benefit from this core's activities.
What this research studies
This core provides biostatistics and bioinformatics support to bring together clinical records, imaging, and bulk- and single-cell molecular data from people with systemic lupus erythematosus (SLE). The team helps design studies, analyzes complex datasets, integrates multiple data types, and shares results across linked projects. They use modern computational methods and the UCSF Data Library infrastructure to make large, multi-modal datasets usable for researchers. By coordinating data generation and analysis, the core aims to make findings from different labs comparable and ready for follow-up studies.
Why it matters
Potential benefit: If successful, this work could speed discovery of biomarkers and treatment targets that improve diagnosis and care for people with lupus.
How similar studies have gone: Integrating clinical and multi-omics data has already produced useful insights in lupus and other autoimmune diseases, although methods continue to improve.
Where this research is happening
-
Feinstein Institute for Medical Research
Manhasset, United States Active
Researchers
- Principal investigator: Sirota, Marina — Feinstein Institute for Medical Research
- Study coordinator: Sirota, Marina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.