Autoimmune Disease Center focus on lupus and immune cell targets
Official title: Administrative Core
Funded at Feinstein Institute for Medical Research · NIH-11520864 · Data updated 2026-11-12
A national program aims to better understand how immune cells drive lupus so doctors can tailor treatments and identify when patients are likely to flare.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project start | May 1, 2019 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $51,582 |
| NIH project number | 5U19AI144306-08 |
| Project ID | NIH-11520864 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with systemic lupus erythematosus who may be eligible for future stratified therapies or observational studies linked to immune profiling.
✕Less likely to help
Patients not meeting future trial criteria or whose disease does not relate to identified immune pathways may see limited direct benefit.
What this research studies
This grant supports a lupus-focused autoimmune center that studies how B cells and myeloid cells contribute to disease flares and remission. By examining disease-specific immune states, researchers hope to improve patient stratification for therapies and identify new treatment targets. The project integrates core activities to translate immunologic insights into options that keep people with lupus in remission and reduce toxic side effects. Patients may see future trials or personalized approaches informed by this work.
Why it matters
Potential benefit: If successful, the work could lead to more effective, safer treatments and better prediction of lupus flares for patients.
How similar studies have gone: Previous research shows that targeting immune cell states can inform therapy choices and predict flares in autoimmune diseases, with growing translational potential.
Where this research is happening
-
Feinstein Institute for Medical Research
Manhasset, United States Active
Researchers
- Principal investigator: Diamond, Betty — Feinstein Institute for Medical Research
- Study coordinator: Diamond, Betty
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.